(93 nodes) Regulation of protein catabolic process network (Atta cephalotes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A158NFN3	Uncharacterized protein. (248 aa)
	A0A158NFT1	F-box domain-containing protein. (392 aa)
	A0A158NG21	Uncharacterized protein. (288 aa)
	A0A158NG97	Protein kinase domain-containing protein. (359 aa)
	A0A158NWE2	AAA domain-containing protein; Belongs to the AAA ATPase family. (253 aa)
	A0A158P2N6	Uncharacterized protein. (157 aa)
	A0A158P2I4	Uncharacterized protein. (350 aa)
	A0A158P1H4	NTR domain-containing protein. (258 aa)
	A0A158P457	Uncharacterized protein. (380 aa)
	A0A158P3Z4	UBR-type domain-containing protein. (5293 aa)
	A0A158P375	Uncharacterized protein; Belongs to the AAA ATPase family. (801 aa)
	A0A158NWA6	RBR-type E3 ubiquitin transferase. (485 aa)
	A0A158NVZ1	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2437 aa)
	A0A158NVW0	WD_REPEATS_REGION domain-containing protein. (523 aa)
	A0A158NVS7	Uncharacterized protein; Belongs to the peptidase C19 family. (385 aa)
	A0A158NVN0	Uncharacterized protein. (392 aa)
	A0A158NVA2	WD_REPEATS_REGION domain-containing protein. (494 aa)
	A0A158NV98	PCI domain-containing protein. (503 aa)
	A0A158NV40	RBR-type E3 ubiquitin transferase. (465 aa)
	A0A158NBJ3	Uncharacterized protein. (915 aa)
	A0A158NV18	Uncharacterized protein. (2127 aa)
	A0A158NUZ5	Uncharacterized protein. (794 aa)
	A0A158NUZ0	Uncharacterized protein. (289 aa)
	A0A158NUV2	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (997 aa)
	A0A158NU42	DDA1 domain-containing protein. (105 aa)
	A0A158NTS3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (440 aa)
	A0A158NTE1	RBR-type E3 ubiquitin transferase. (470 aa)
	A0A158NSQ3	Protein kinase domain-containing protein. (315 aa)
	A0A158NSK4	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	A0A158NSG2	Uncharacterized protein. (546 aa)
	A0A158NSC6	AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa)
	A0A158NS99	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (189 aa)
	A0A158NRI3	Uncharacterized protein. (683 aa)
	A0A158NQW6	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (893 aa)
	A0A158NQA1	Ubiquitin-like domain-containing protein. (499 aa)
	A0A158NPS9	Nefa_Nip30_N domain-containing protein. (279 aa)
	A0A158NP28	Uncharacterized protein; Belongs to the DEAD box helicase family. (423 aa)
	A0A158NNN9	Uncharacterized protein. (164 aa)
	A0A158NNI4	Uncharacterized protein. (794 aa)
	A0A158NAE0	Uncharacterized protein. (1048 aa)
	A0A158NAX4	MPN domain-containing protein. (383 aa)
	A0A158NB94	Uncharacterized protein. (526 aa)
	A0A158NBH9	RBR-type E3 ubiquitin transferase. (506 aa)
	A0A158NGK5	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (927 aa)
	A0A158NGL5	Ubiquitin-like domain-containing protein. (112 aa)
	A0A158NGR2	Uncharacterized protein. (2182 aa)
	A0A158NGW5	Uncharacterized protein. (281 aa)
	A0A158NH94	CULLIN_2 domain-containing protein; Belongs to the cullin family. (698 aa)
	A0A158NHU2	Uncharacterized protein. (817 aa)
	A0A158NI21	Ubiquitin carboxyl-terminal hydrolase. (803 aa)
	A0A158NBI2	Uncharacterized protein. (429 aa)
	A0A158N8W4	PITH domain-containing protein. (199 aa)
	A0A158N8X3	RBR-type E3 ubiquitin transferase. (500 aa)
	A0A158N9U7	FERM domain-containing protein. (1225 aa)
	A0A158NWW9	Prot_ATP_ID_OB domain-containing protein. (191 aa)
	A0A158NX66	Uncharacterized protein. (80 aa)
	A0A158NA13	Rhomboid domain-containing protein. (246 aa)
	A0A158NA71	ANK_REP_REGION domain-containing protein. (230 aa)
	A0A158NI91	BZIP domain-containing protein. (455 aa)
	A0A158NI96	Uncharacterized protein. (545 aa)
	A0A158NIH9	Uncharacterized protein. (2036 aa)
	A0A158NJ58	CPSF_A domain-containing protein. (1141 aa)
	A0A158NBR4	Uncharacterized protein. (766 aa)
	A0A158NBV8	TPR_REGION domain-containing protein. (295 aa)
	A0A158NC73	Uncharacterized protein. (555 aa)
	A0A158NCM8	Uncharacterized protein. (581 aa)
	A0A158NCP9	RIC1 domain-containing protein. (1416 aa)
	A0A158NDG2	Uncharacterized protein. (202 aa)
	A0A158NDK7	E3 ubiquitin-protein ligase. (872 aa)
	A0A158NDT7	Uncharacterized protein. (529 aa)
	A0A158NFG5	Uncharacterized protein. (785 aa)
	A0A158NJD9	Uncharacterized protein. (2828 aa)
	A0A158NKQ6	Ubiquitin carboxyl-terminal hydrolase. (932 aa)
	A0A158NM67	Muskelin_N domain-containing protein. (752 aa)
	A0A158NM76	Uncharacterized protein. (547 aa)
	A0A158NMH3	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1019 aa)
	A0A158NMP9	Uncharacterized protein. (517 aa)
	A0A158NMX7	Uncharacterized protein. (401 aa)
	A0A158NNI3	USP domain-containing protein; Belongs to the peptidase C19 family. (1324 aa)
	A0A158NY24	RBR-type E3 ubiquitin transferase. (791 aa)
	A0A158NYQ6	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (187 aa)
	A0A158NZ41	Poly [ADP-ribose] polymerase. (1211 aa)
	A0A158NZC0	Uncharacterized protein. (324 aa)
	A0A158NZF3	Uncharacterized protein. (679 aa)
	A0A158NZX6	Uncharacterized protein. (228 aa)
	A0A158P021	PCI domain-containing protein. (411 aa)
	A0A158P094	Uncharacterized protein. (399 aa)
	A0A158P1E9	AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
	A0A158P2T2	Uncharacterized protein. (669 aa)
	A0A158P2X5	CULLIN_2 domain-containing protein; Belongs to the cullin family. (752 aa)
	A0A158NWF7	AAA domain-containing protein; Belongs to the AAA ATPase family. (415 aa)
	A0A158NWK0	RING-type domain-containing protein. (457 aa)
	A0A158NFM1	AAA domain-containing protein; Belongs to the AAA ATPase family. (480 aa)

Your Current Organism:

Atta cephalotes

NCBI taxonomy Id: 12957
Other names: A. cephalotes

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A158N8X3	A0A158NWA6	RBR-type E3 ubiquitin transferase.	RBR-type E3 ubiquitin transferase.	0.410
A0A158N9U7	A0A158NV18	FERM domain-containing protein.	Uncharacterized protein.	0.956
A0A158NA13	A0A158P375	Rhomboid domain-containing protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.691
A0A158NA71	A0A158NFM1	ANK_REP_REGION domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.994
A0A158NA71	A0A158NGK5	ANK_REP_REGION domain-containing protein.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.852
A0A158NA71	A0A158NMH3	ANK_REP_REGION domain-containing protein.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.993
A0A158NA71	A0A158NQW6	ANK_REP_REGION domain-containing protein.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.852
A0A158NA71	A0A158NSC6	ANK_REP_REGION domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.995
A0A158NA71	A0A158NUZ0	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.457
A0A158NA71	A0A158NV98	ANK_REP_REGION domain-containing protein.	PCI domain-containing protein.	0.971
A0A158NA71	A0A158NVS7	ANK_REP_REGION domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C19 family.	0.780
A0A158NA71	A0A158NWE2	ANK_REP_REGION domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.995
A0A158NA71	A0A158NWF7	ANK_REP_REGION domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.995
A0A158NA71	A0A158NWW9	ANK_REP_REGION domain-containing protein.	Prot_ATP_ID_OB domain-containing protein.	0.995
A0A158NA71	A0A158P1E9	ANK_REP_REGION domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.995
A0A158NA71	A0A158P2N6	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.505
A0A158NAE0	A0A158NB94	Uncharacterized protein.	Uncharacterized protein.	0.558
A0A158NAE0	A0A158NHU2	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A158NAX4	A0A158NDG2	MPN domain-containing protein.	Uncharacterized protein.	0.464
A0A158NAX4	A0A158NGK5	MPN domain-containing protein.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.599