STRINGSTRING
I206_04077 I206_04077 I206_04223 I206_04223 I206_04153 I206_04153 I206_04329 I206_04329 I206_04349 I206_04349 I206_04395 I206_04395 I206_04391 I206_04391 I206_04477 I206_04477 I206_04399 I206_04399 I206_04516 I206_04516 I206_03387 I206_03387 I206_03456 I206_03456 I206_03445 I206_03445 I206_03478 I206_03478 I206_03479 I206_03479 I206_03526 I206_03526 I206_03629 I206_03629 PSD1 PSD1 I206_03839 I206_03839 I206_03854 I206_03854 I206_03928 I206_03928 I206_02687 I206_02687 I206_02704 I206_02704 I206_01233 I206_01233 I206_02735 I206_02735 I206_02743 I206_02743 I206_02780 I206_02780 I206_02826 I206_02826 I206_02812 I206_02812 I206_02846 I206_02846 I206_02897 I206_02897 I206_02878 I206_02878 I206_03027 I206_03027 I206_03048 I206_03048 I206_03095 I206_03095 I206_03235 I206_03235 I206_02009 I206_02009 I206_02006 I206_02006 I206_03277 I206_03277 I206_03343 I206_03343 I206_02040 I206_02040 I206_02086 I206_02086 I206_02127 I206_02127 I206_02122 I206_02122 I206_02199 I206_02199 I206_02229 I206_02229 I206_02254 I206_02254 I206_02301 I206_02301 I206_02360 I206_02360 I206_02433 I206_02433 I206_01282 I206_01282 I206_01427 I206_01427 I206_01275 I206_01275 I206_01541 I206_01541 I206_01596 I206_01596 I206_01559 I206_01559 I206_01628 I206_01628 I206_01595 I206_01595 I206_01735 I206_01735 I206_01592 I206_01592 I206_01670 I206_01670 I206_01710 I206_01710 I206_01988 I206_01988 I206_01991 I206_01991 I206_01794 I206_01794 I206_01876 I206_01876 I206_00183 I206_00183 I206_00229 I206_00229 I206_01980 I206_01980 I206_01973 I206_01973 I206_00286 I206_00286 I206_00077 I206_00077 I206_00202 I206_00202 I206_00382 I206_00382 I206_00650 I206_00650 I206_00472 I206_00472 I206_00441 I206_00441 I206_00814 I206_00814 I206_00605 I206_00605 I206_00964 I206_00964 I206_00788 I206_00788 I206_00911 I206_00911 I206_00881 I206_00881 I206_00891 I206_00891 I206_00971 I206_00971 I206_00882 I206_00882 I206_01011 I206_01011 I206_01063 I206_01063 I206_00946 I206_00946 I206_01054 I206_01054 I206_07841 I206_07841 I206_07893 I206_07893 I206_07765 I206_07765 I206_07778 I206_07778 I206_07808 I206_07808 I206_07590 I206_07590 I206_07588 I206_07588 I206_07621 I206_07621 I206_07646 I206_07646 I206_07687 I206_07687 I206_07322 I206_07322 I206_07349 I206_07349 I206_07453 I206_07453 I206_07470 I206_07470 I206_07515 I206_07515 I206_07103 I206_07103 I206_07117 I206_07117 I206_07135 I206_07135 I206_07159 I206_07159 I206_07184 I206_07184 I206_07183 I206_07183 I206_07254 I206_07254 I206_07263 I206_07263 I206_07294 I206_07294 I206_06808 I206_06808 PSD2 PSD2 I206_06979 I206_06979 I206_06996 I206_06996 I206_07032 I206_07032 I206_07036 I206_07036 I206_07080 I206_07080 I206_07094 I206_07094 I206_06338 I206_06338 I206_06405 I206_06405 I206_06569 I206_06569 I206_06564 I206_06564 I206_06652 I206_06652 I206_06650 I206_06650 I206_05727 I206_05727 I206_05820 I206_05820 I206_05813 I206_05813 I206_05869 I206_05869 I206_05921 I206_05921 I206_06016 I206_06016 I206_06075 I206_06075 I206_06176 I206_06176 I206_05164 I206_05164 I206_05284 I206_05284 I206_05314 I206_05314 I206_05412 I206_05412 I206_05453 I206_05453 I206_05584 I206_05584 I206_05522 I206_05522 I206_05549 I206_05549 I206_05559 I206_05559 I206_05620 I206_05620 I206_01117 I206_01117 I206_04606 I206_04606 I206_04599 I206_04599 I206_04651 I206_04651 I206_04691 I206_04691 I206_04781 I206_04781 I206_04825 I206_04825 I206_04907 I206_04907 I206_05003 I206_05003 I206_04939 I206_04939 I206_05075 I206_05075 I206_05068 I206_05068 I206_05054 I206_05054 I206_04053 I206_04053
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I206_04077Delta14-sterol reductase. (490 aa)
I206_04223Isopentenyl-diphosphate delta-isomerase. (255 aa)
I206_04153FAD-binding FR-type domain-containing protein. (361 aa)
I206_04329Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (404 aa)
I206_04349Uncharacterized protein. (477 aa)
I206_04395Lysophospholipid acyltransferase; Belongs to the membrane-bound acyltransferase family. (586 aa)
I206_043913'(2'),5'-bisphosphate nucleotidase. (358 aa)
I206_04477Beta-1,2-xylosyltransferase 1. (701 aa)
I206_04399Uncharacterized protein. (478 aa)
I206_04516Phospholipid:diacylglycerol acyltransferase. (738 aa)
I206_03387Amino_oxidase domain-containing protein. (666 aa)
I206_03456Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (375 aa)
I206_03445Acyl-CoA-dependent ceramide synthase. (411 aa)
I206_03478Fatty acid synthase subunit alpha. (1434 aa)
I206_03479Fatty acid synthase subunit beta. (2519 aa)
I206_03526HAD hydrolase. (372 aa)
I206_03629Glyco_transf_28 domain-containing protein. (1223 aa)
PSD1Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (529 aa)
I206_03839Uncharacterized protein. (562 aa)
I206_03854Atypical/PI4K protein kinase; Belongs to the PI3/PI4-kinase family. (1138 aa)
I206_039283-ketodihydrosphingosine reductase TSC10. (352 aa)
I206_02687Uncharacterized protein. (134 aa)
I206_02704Uncharacterized protein. (441 aa)
I206_01233Uncharacterized protein. (414 aa)
I206_02735Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
I206_02743Farnesyl-diphosphate farnesyltransferase. (518 aa)
I206_02780MIPC synthase. (845 aa)
I206_02826Serine palmitoyltransferase. (718 aa)
I206_02812Uncharacterized protein. (531 aa)
I206_02846CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (250 aa)
I206_02897Myo-inositol-1-phosphate synthase. (569 aa)
I206_02878Phosphatidylinositol phosphate phosphatase. (1326 aa)
I206_03027Inositol phosphorylsphingolipid-phospholipase C. (536 aa)
I206_03048Phosphatidylinositol glycan, class O. (1026 aa)
I206_030954-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (403 aa)
I206_03235Phosphatidylinositol glycan, class C. (368 aa)
I206_02009Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC). (325 aa)
I206_02006Squalene monooxygenase. (544 aa)
I206_03277Cytochrome b5; Belongs to the cytochrome b5 family. (140 aa)
I206_03343NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (366 aa)
I206_02040Phospholipase D. (1811 aa)
I206_020861-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (798 aa)
I206_02127Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (395 aa)
I206_02122Dihydroceramidase. (294 aa)
I206_02199Alkyl transferase; Belongs to the UPP synthase family. (286 aa)
I206_022291-phosphatidylinositol-3-phosphate 5-kinase. (2523 aa)
I206_02254D-erythro-sphingosine kinase. (601 aa)
I206_02301Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (722 aa)
I206_02360Vacuole morphology and inheritance protein 14. (1084 aa)
I206_02433Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (157 aa)
I206_01282Uncharacterized protein. (247 aa)
I206_01427Acyl-CoA-dependent ceramide synthase. (431 aa)
I206_01275Geranylgeranyl diphosphate synthase, type III; Belongs to the FPP/GGPP synthase family. (326 aa)
I206_01541Glyco_transf_28 domain-containing protein. (543 aa)
I206_01596Tafazzin family protein; Belongs to the taffazin family. (343 aa)
I206_01559Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (259 aa)
I206_01628Uncharacterized protein. (409 aa)
I206_01595Phosphatidylinositol 3-kinase VPS34. (909 aa)
I206_01735GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity. (441 aa)
I206_01592Sterol 24-C-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family. (343 aa)
I206_01670L-carnitine dehydratase/bile acid-inducible protein F. (460 aa)
I206_01710C4-hydroxylase; Belongs to the sterol desaturase family. (355 aa)
I206_01988Kinase; Belongs to the inositol phosphokinase (IPK) family. (1337 aa)
I206_01991Uncharacterized protein. (211 aa)
I206_01794Uncharacterized protein. (696 aa)
I206_01876Integral membrane protein. (525 aa)
I206_00183Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. (95 aa)
I206_00229Choline-phosphate cytidylyltransferase. (466 aa)
I206_019803-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (499 aa)
I206_01973Uncharacterized protein. (91 aa)
I206_00286acidPPc domain-containing protein. (220 aa)
I206_00077Lathosterol oxidase; Belongs to the sterol desaturase family. (337 aa)
I206_002021-phosphatidylinositol-4-phosphate 5-kinase. (1002 aa)
I206_00382MSP domain-containing protein. (308 aa)
I206_00650Capsular associated protein. (643 aa)
I206_004721-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (360 aa)
I206_00441Mannosyltransferase. (614 aa)
I206_00814CDP-diacylglycerol-inositol 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (314 aa)
I206_00605Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily. (377 aa)
I206_00964Uncharacterized protein. (545 aa)
I206_00788Uncharacterized protein. (537 aa)
I206_00911PIPK domain-containing protein. (1730 aa)
I206_00881Kinase; Belongs to the inositol phosphokinase (IPK) family. (506 aa)
I206_00891Delta24(24(1))-sterol reductase. (495 aa)
I206_00971CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. (583 aa)
I206_00882Uncharacterized protein. (196 aa)
I206_01011Glycerol-3-phosphate O-acyltransferase/dihydroxyacetone phosphate acyltransferase. (769 aa)
I206_01063Uncharacterized protein. (411 aa)
I206_00946Sterol 3-beta-glucosyltransferase; Belongs to the glycosyltransferase 28 family. (1517 aa)
I206_01054GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (434 aa)
I206_07841Uncharacterized protein. (696 aa)
I206_07893Cardiolipin synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (308 aa)
I206_07765Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. (362 aa)
I206_07778Glycosylphosphatidylinositol transamidase. (550 aa)
I206_07808Inositolphosphorylceramide synthase. (497 aa)
I206_07590Elongation of fatty acids protein. (324 aa)
I206_07588Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (408 aa)
I206_07621Uncharacterized protein. (287 aa)
I206_07646Uncharacterized protein. (228 aa)
I206_07687Dolichyldiphosphatase. (253 aa)
I206_07322Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (515 aa)
I206_07349Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates; Belongs to the fatty acid desaturase type 1 family. (487 aa)
I206_07453LNS2 domain-containing protein. (1024 aa)
I206_07470Uncharacterized protein. (283 aa)
I206_07515Inositol-1-monophosphatase. (306 aa)
I206_07103Uncharacterized protein. (368 aa)
I206_07117C-8 sterol isomerase. (249 aa)
I206_07135Phosphatidylserine decarboxylase. (441 aa)
I206_07159Serine palmitoyltransferase. (542 aa)
I206_07184Uncharacterized protein. (333 aa)
I206_07183Uncharacterized protein. (424 aa)
I206_07254RIBOSOMAL_L9 domain-containing protein. (218 aa)
I206_072633-keto sterol reductase. (442 aa)
I206_07294Sphingolipid delta-4 desaturase. (464 aa)
I206_06808Uncharacterized protein. (278 aa)
PSD2Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (1288 aa)
I206_06979Stearoyl-CoA desaturase (Delta-9 desaturase). (586 aa)
I206_06996Uncharacterized protein. (429 aa)
I206_07032ATP-citrate synthase subunit 1. (1149 aa)
I206_07036Short-chain dehydrogenase. (242 aa)
I206_07080Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (76 aa)
I206_07094Sterol-4alpha-carboxylate 3-dehydrogenase (Decarboxylating). (433 aa)
I206_06338Phosphatidate cytidylyltransferase; Belongs to the CDS family. (641 aa)
I206_06405NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (753 aa)
I206_06569PIG-P domain-containing protein. (191 aa)
I206_06564Phosphatidylserine decarboxylase. (397 aa)
I206_06652Ethanolaminephosphotransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (430 aa)
I206_066503-hydroxy-3-methylglutaryl coenzyme A reductase. (1287 aa)
I206_05727Cardiolipin-specific phospholipase. (566 aa)
I206_05820Polyphosphoinositide phosphatase. (856 aa)
I206_05813Phospholipase. (860 aa)
I206_05869Uncharacterized protein. (655 aa)
I206_05921Hexaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. (498 aa)
I206_06016Inositol-1-monophosphatase. (318 aa)
I206_06075Enoyl reductase. (312 aa)
I206_06176Zn(2)-C6 fungal-type domain-containing protein. (637 aa)
I206_05164Kinase; Belongs to the inositol phosphokinase (IPK) family. (417 aa)
I206_05284GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (398 aa)
I206_05314C-22 sterol desaturase; Belongs to the cytochrome P450 family. (529 aa)
I206_05412DAGKc domain-containing protein. (423 aa)
I206_05453Uncharacterized protein. (672 aa)
I206_05584Uncharacterized protein. (296 aa)
I206_055222-acylglycerol O-acyltransferase 2. (488 aa)
I206_05549Acetyl-CoA carboxylase/biotin carboxylase. (2234 aa)
I206_05559Glycerol transporter; Belongs to the membrane-bound acyltransferase family. (572 aa)
I206_05620Uncharacterized protein. (216 aa)
I206_01117Methylsterol monooxygenase; Belongs to the sterol desaturase family. (351 aa)
I206_04606TYR_PHOSPHATASE_2 domain-containing protein. (854 aa)
I206_04599Hydrolase_4 domain-containing protein. (289 aa)
I206_04651Uncharacterized protein. (1177 aa)
I206_04691Uncharacterized protein. (605 aa)
I206_04781Uncharacterized protein. (988 aa)
I206_04825Phosphatidylinositol 4-kinase; Belongs to the PI3/PI4-kinase family. (2010 aa)
I206_04907Calcofluor white hypersensitive protein. (999 aa)
I206_05003Sacchrp_dh_NADP domain-containing protein. (440 aa)
I206_04939Choline kinase. (532 aa)
I206_05075Uncharacterized protein. (456 aa)
I206_05068Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family. (1225 aa)
I206_05054Glyco_transf_28 domain-containing protein. (930 aa)
I206_04053Cytochrome P450, family 51 (Sterol 14-demethylase); Belongs to the cytochrome P450 family. (553 aa)
Your Current Organism:
Kwoniella pini
NCBI taxonomy Id: 1296096
Other names: Cryptococcus pinus CBS 10737, Cryptococcus pinus CBS10737, K. pini CBS 10737, Kwoniella pini CBS 10737
Server load: low (40%) [HD]