STRINGSTRING
I302_09043 I302_09043 I302_09113 I302_09113 I302_09161 I302_09161 I302_08552 I302_08552 I302_08567 I302_08567 I302_08709 I302_08709 I302_08778 I302_08778 I302_07794 I302_07794 I302_07828 I302_07828 I302_08143 I302_08143 I302_06555 I302_06555 I302_06651 I302_06651 I302_06691 I302_06691 I302_05736 I302_05736 I302_05843 I302_05843 I302_06133 I302_06133 I302_04912 I302_04912 I302_05210 I302_05210 I302_05251 I302_05251 I302_03810 I302_03810 I302_04227 I302_04227 I302_02179 I302_02179 I302_02384 I302_02384 I302_02388 I302_02388 I302_00057 I302_00057 I302_01327 I302_01327 I302_01471 I302_01471
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I302_09043Uncharacterized protein. (780 aa)
I302_091133'-5' exonuclease domain-containing protein. (287 aa)
I302_09161Uncharacterized protein. (341 aa)
I302_08552Uncharacterized protein. (903 aa)
I302_08567ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (903 aa)
I302_08709Uncharacterized protein. (583 aa)
I302_08778Uncharacterized protein. (844 aa)
I302_07794Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (712 aa)
I302_07828Uncharacterized protein. (678 aa)
I302_08143Uncharacterized protein. (992 aa)
I302_06555DNA replication ATP-dependent helicase Dna2. (1348 aa)
I302_06651Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2240 aa)
I302_06691DUF1767 domain-containing protein. (561 aa)
I302_05736DNA repair protein RAD50. (1357 aa)
I302_05843Replication factor A2. (256 aa)
I302_06133Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (612 aa)
I302_04912AAA domain-containing protein. (1021 aa)
I302_05210AAA domain-containing protein. (379 aa)
I302_05251zf-GRF domain-containing protein. (280 aa)
I302_03810DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (971 aa)
I302_04227BRCT domain-containing protein. (1312 aa)
I302_02179Checkpoint protein; Belongs to the HUS1 family. (294 aa)
I302_02384RECA_2 domain-containing protein. (582 aa)
I302_02388BRCT domain-containing protein. (872 aa)
I302_00057Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (3043 aa)
I302_01327Uncharacterized protein. (1454 aa)
I302_01471DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (344 aa)
Your Current Organism:
Kwoniella bestiolae
NCBI taxonomy Id: 1296100
Other names: Cryptococcus bestiolae CBS 10118, Cryptococcus bestiolae CBS10118, K. bestiolae CBS 10118, Kwoniella bestiolae CBS 10118
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.