47 items (Kwoniella bestiolae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I302_05843	Replication factor A2. (256 aa)
	I302_08905	DNA polymerase. (1981 aa)
	I302_08997	ERCC4 domain-containing protein. (840 aa)
	I302_09050	DNA helicase; Belongs to the MCM family. (961 aa)
	I302_09111	3'-5' exonuclease domain-containing protein. (270 aa)
	I302_09144	DNA helicase; Belongs to the MCM family. (736 aa)
	I302_08584	Uncharacterized protein. (948 aa)
	I302_08709	Uncharacterized protein. (583 aa)
	I302_07766	DNA repair protein Swi5/Sae3. (104 aa)
	I302_07913	Cell division control protein 45. (712 aa)
	I302_08143	Uncharacterized protein. (992 aa)
	I302_06465	Deacetylase sirtuin-type domain-containing protein. (466 aa)
	I302_06691	DUF1767 domain-containing protein. (561 aa)
	I302_06852	DNA replication complex GINS protein PSF1. (230 aa)
	I302_06947	DNA helicase; Belongs to the MCM family. (934 aa)
	I302_05634	WD_REPEATS_REGION domain-containing protein. (1244 aa)
	I302_05671	26S proteasome complex subunit DSS1. (107 aa)
	I302_05781	Helicase C-terminal domain-containing protein. (194 aa)
	I302_05897	SMC_N domain-containing protein. (1155 aa)
	I302_06043	DNA repair and recombination protein RAD54-like protein. (817 aa)
	I302_06133	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (612 aa)
	I302_06132	SP-RING-type domain-containing protein. (313 aa)
	I302_06193	SMC_N domain-containing protein. (1165 aa)
	I302_04734	DNA helicase; Belongs to the MCM family. (868 aa)
	I302_05132	Deacetylase sirtuin-type domain-containing protein. (567 aa)
	I302_05210	AAA domain-containing protein. (379 aa)
	SLX1	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (330 aa)
	I302_04095	Uncharacterized protein. (637 aa)
	I302_04154	Uncharacterized protein. (348 aa)
	I302_04634	SWIM-type domain-containing protein. (248 aa)
	I302_04672	Uncharacterized protein. (580 aa)
	I302_02030	Serine/threonine-protein phosphatase. (308 aa)
	I302_02179	Checkpoint protein; Belongs to the HUS1 family. (294 aa)
	I302_02384	RECA_2 domain-containing protein. (582 aa)
	I302_02774	zf-RING-like domain-containing protein. (365 aa)
	I302_02896	Uncharacterized protein. (1087 aa)
	I302_02960	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (199 aa)
	I302_03303	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1021 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (794 aa)
	I302_00404	DNA excision repair protein ERCC-4. (1128 aa)
	I302_00679	Uncharacterized protein. (309 aa)
	I302_00726	Uncharacterized protein. (703 aa)
	I302_01327	Uncharacterized protein. (1454 aa)
	I302_01324	DNA helicase; Belongs to the MCM family. (997 aa)
	I302_01471	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (344 aa)
	I302_01575	DUF3421 domain-containing protein. (396 aa)
	I302_01553	CDC7 protein kinase. (898 aa)

Your Current Organism:

Kwoniella bestiolae

NCBI taxonomy Id: 1296100
Other names: Cryptococcus bestiolae CBS 10118, Cryptococcus bestiolae CBS10118, K. bestiolae CBS 10118, Kwoniella bestiolae CBS 10118

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I302_00404	I302_01327	A0A1B9GD17	A0A1B9GFI6	DNA excision repair protein ERCC-4.	Uncharacterized protein.	0.829
I302_00404	I302_01471	A0A1B9GD17	A0A1B9GG16	DNA excision repair protein ERCC-4.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.923
I302_00404	I302_02179	A0A1B9GD17	A0A1B9G8I3	DNA excision repair protein ERCC-4.	Checkpoint protein; Belongs to the HUS1 family.	0.633
I302_00404	I302_02384	A0A1B9GD17	A0A1B9G938	DNA excision repair protein ERCC-4.	RECA_2 domain-containing protein.	0.783
I302_00404	I302_02896	A0A1B9GD17	A0A1B9GAL4	DNA excision repair protein ERCC-4.	Uncharacterized protein.	0.615
I302_00404	I302_03303	A0A1B9GD17	A0A1B9GBQ6	DNA excision repair protein ERCC-4.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.734
I302_00404	I302_05210	A0A1B9GD17	A0A1B9G310	DNA excision repair protein ERCC-4.	AAA domain-containing protein.	0.766
I302_00404	I302_05634	A0A1B9GD17	A0A1B9FZI7	DNA excision repair protein ERCC-4.	WD_REPEATS_REGION domain-containing protein.	0.555
I302_00404	I302_05781	A0A1B9GD17	A0A1B9FZY2	DNA excision repair protein ERCC-4.	Helicase C-terminal domain-containing protein.	0.615
I302_00404	I302_05843	A0A1B9GD17	A0A1B9G040	DNA excision repair protein ERCC-4.	Replication factor A2.	0.858
I302_00404	I302_06043	A0A1B9GD17	A0A1B9G0N7	DNA excision repair protein ERCC-4.	DNA repair and recombination protein RAD54-like protein.	0.615
I302_00404	I302_06133	A0A1B9GD17	A0A1B9G0X3	DNA excision repair protein ERCC-4.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.968
I302_00404	I302_06193	A0A1B9GD17	A0A1B9G130	DNA excision repair protein ERCC-4.	SMC_N domain-containing protein.	0.457
I302_00404	I302_06691	A0A1B9GD17	A0A1B9FY54	DNA excision repair protein ERCC-4.	DUF1767 domain-containing protein.	0.929
I302_00404	I302_08143	A0A1B9GD17	A0A1B9FUP7	DNA excision repair protein ERCC-4.	Uncharacterized protein.	0.647
I302_00404	I302_08584	A0A1B9GD17	A0A1B9FSR2	DNA excision repair protein ERCC-4.	Uncharacterized protein.	0.713
I302_00404	I302_08709	A0A1B9GD17	A0A1B9FT47	DNA excision repair protein ERCC-4.	Uncharacterized protein.	0.961
I302_00404	I302_08905	A0A1B9GD17	A0A1B9FR34	DNA excision repair protein ERCC-4.	DNA polymerase.	0.837
I302_00404	I302_08997	A0A1B9GD17	A0A1B9FRD3	DNA excision repair protein ERCC-4.	ERCC4 domain-containing protein.	0.940
I302_00404	I302_09050	A0A1B9GD17	A0A1B9FRI3	DNA excision repair protein ERCC-4.	DNA helicase; Belongs to the MCM family.	0.476