28 items (Kwoniella bestiolae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I302_01327	Uncharacterized protein. (1454 aa)
	I302_01345	Meiotic recombinase Dmc1; Belongs to the RecA family. (333 aa)
	I302_08997	ERCC4 domain-containing protein. (840 aa)
	I302_08236	Meiotic Sister-Chromatid recombination aldehyde dehydrogenase. (634 aa)
	I302_08280	RING-type domain-containing protein. (476 aa)
	I302_07615	Uncharacterized protein. (957 aa)
	I302_06461	DNA mismatch repair protein MLH1. (712 aa)
	I302_06691	DUF1767 domain-containing protein. (561 aa)
	I302_05781	Helicase C-terminal domain-containing protein. (194 aa)
	I302_06043	DNA repair and recombination protein RAD54-like protein. (817 aa)
	I302_06133	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (612 aa)
	I302_04726	Uncharacterized protein. (1424 aa)
	I302_04778	TP6A_N domain-containing protein. (688 aa)
	I302_01471	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (344 aa)
	I302_05208	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1495 aa)
	I302_05210	AAA domain-containing protein. (379 aa)
	I302_05231	DNA_MISMATCH_REPAIR_2 domain-containing protein. (850 aa)
	I302_03810	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (971 aa)
	I302_04672	Uncharacterized protein. (580 aa)
	I302_02190	PLK/PLK1 protein kinase. (795 aa)
	I302_02336	Uncharacterized protein. (348 aa)
	I302_02436	TBPIP domain-containing protein. (279 aa)
	I302_02525	AAA domain-containing protein; Belongs to the AAA ATPase family. (584 aa)
	I302_02594	ERCC4 domain-containing protein. (595 aa)
	I302_02772	Meiotic nuclear division protein 1; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (204 aa)
	I302_02896	Uncharacterized protein. (1087 aa)
	I302_01553	CDC7 protein kinase. (898 aa)
	I302_00404	DNA excision repair protein ERCC-4. (1128 aa)

Your Current Organism:

Kwoniella bestiolae

NCBI taxonomy Id: 1296100
Other names: Cryptococcus bestiolae CBS 10118, Cryptococcus bestiolae CBS10118, K. bestiolae CBS 10118, Kwoniella bestiolae CBS 10118

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I302_00404	I302_01327	A0A1B9GD17	A0A1B9GFI6	DNA excision repair protein ERCC-4.	Uncharacterized protein.	0.829
I302_00404	I302_01345	A0A1B9GD17	A0A1B9GFL2	DNA excision repair protein ERCC-4.	Meiotic recombinase Dmc1; Belongs to the RecA family.	0.679
I302_00404	I302_01471	A0A1B9GD17	A0A1B9GG16	DNA excision repair protein ERCC-4.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.923
I302_00404	I302_02190	A0A1B9GD17	A0A1B9G8K5	DNA excision repair protein ERCC-4.	PLK/PLK1 protein kinase.	0.593
I302_00404	I302_02594	A0A1B9GD17	A0A1B9G9P2	DNA excision repair protein ERCC-4.	ERCC4 domain-containing protein.	0.588
I302_00404	I302_02896	A0A1B9GD17	A0A1B9GAL4	DNA excision repair protein ERCC-4.	Uncharacterized protein.	0.615
I302_00404	I302_03810	A0A1B9GD17	A0A1B9G547	DNA excision repair protein ERCC-4.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.903
I302_00404	I302_04778	A0A1B9GD17	A0A1B9G1U9	DNA excision repair protein ERCC-4.	TP6A_N domain-containing protein.	0.606
I302_00404	I302_05210	A0A1B9GD17	A0A1B9G310	DNA excision repair protein ERCC-4.	AAA domain-containing protein.	0.766
I302_00404	I302_05231	A0A1B9GD17	A0A1B9G327	DNA excision repair protein ERCC-4.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.519
I302_00404	I302_05781	A0A1B9GD17	A0A1B9FZY2	DNA excision repair protein ERCC-4.	Helicase C-terminal domain-containing protein.	0.615
I302_00404	I302_06043	A0A1B9GD17	A0A1B9G0N7	DNA excision repair protein ERCC-4.	DNA repair and recombination protein RAD54-like protein.	0.615
I302_00404	I302_06133	A0A1B9GD17	A0A1B9G0X3	DNA excision repair protein ERCC-4.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.968
I302_00404	I302_06461	A0A1B9GD17	A0A1B9FXH8	DNA excision repair protein ERCC-4.	DNA mismatch repair protein MLH1.	0.514
I302_00404	I302_06691	A0A1B9GD17	A0A1B9FY54	DNA excision repair protein ERCC-4.	DUF1767 domain-containing protein.	0.929
I302_00404	I302_08997	A0A1B9GD17	A0A1B9FRD3	DNA excision repair protein ERCC-4.	ERCC4 domain-containing protein.	0.940
I302_01327	I302_00404	A0A1B9GFI6	A0A1B9GD17	Uncharacterized protein.	DNA excision repair protein ERCC-4.	0.829
I302_01327	I302_01345	A0A1B9GFI6	A0A1B9GFL2	Uncharacterized protein.	Meiotic recombinase Dmc1; Belongs to the RecA family.	0.964
I302_01327	I302_01471	A0A1B9GFI6	A0A1B9GG16	Uncharacterized protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.997
I302_01327	I302_02190	A0A1B9GFI6	A0A1B9G8K5	Uncharacterized protein.	PLK/PLK1 protein kinase.	0.764