STRINGSTRING
I302_06040 I302_06040 I302_02096 I302_02096 I302_02190 I302_02190 I302_02212 I302_02212 I302_02223 I302_02223 I302_02316 I302_02316 I302_02318 I302_02318 I302_02345 I302_02345 I302_02412 I302_02412 I302_02451 I302_02451 I302_02591 I302_02591 I302_02704 I302_02704 I302_02700 I302_02700 I302_02765 I302_02765 I302_02894 I302_02894 I302_03000 I302_03000 I302_03025 I302_03025 I302_03138 I302_03138 I302_03156 I302_03156 I302_03219 I302_03219 I302_03218 I302_03218 I302_03254 I302_03254 I302_00045 I302_00045 I302_00066 I302_00066 I302_00193 I302_00193 I302_00188 I302_00188 I302_00206 I302_00206 I302_00207 I302_00207 I302_00279 I302_00279 I302_00293 I302_00293 I302_00306 I302_00306 I302_00391 I302_00391 I302_00421 I302_00421 I302_00578 I302_00578 I302_00586 I302_00586 I302_00587 I302_00587 I302_00687 I302_00687 I302_00703 I302_00703 I302_00707 I302_00707 I302_00727 I302_00727 I302_00815 I302_00815 I302_00837 I302_00837 I302_00934 I302_00934 I302_00962 I302_00962 I302_00970 I302_00970 I302_01074 I302_01074 I302_01066 I302_01066 I302_01303 I302_01303 I302_01460 I302_01460 I302_01470 I302_01470 I302_01398 I302_01398 I302_01572 I302_01572 I302_01622 I302_01622 I302_01693 I302_01693 I302_01781 I302_01781 I302_02097 I302_02097 I302_02094 I302_02094 I302_02050 I302_02050 I302_02023 I302_02023 I302_01874 I302_01874 I302_04658 I302_04658 I302_04581 I302_04581 I302_04555 I302_04555 I302_04525 I302_04525 I302_04315 I302_04315 I302_04218 I302_04218 I302_04227 I302_04227 I302_04230 I302_04230 I302_04168 I302_04168 SUS1 SUS1 I302_04127 I302_04127 I302_04057 I302_04057 I302_03938 I302_03938 I302_03911 I302_03911 I302_03875 I302_03875 I302_03793 I302_03793 I302_03740 I302_03740 I302_03732 I302_03732 I302_03698 I302_03698 I302_03647 I302_03647 I302_03671 I302_03671 I302_03564 I302_03564 I302_03572 I302_03572 I302_03506 I302_03506 I302_03405 I302_03405 I302_03416 I302_03416 I302_03388 I302_03388 I302_05507 I302_05507 I302_05429 I302_05429 MED10 MED10 I302_05363 I302_05363 I302_05220 I302_05220 KAE1 KAE1 MED6 MED6 I302_05139 I302_05139 I302_05073 I302_05073 I302_04988 I302_04988 I302_04896 I302_04896 I302_04865 I302_04865 I302_04864 I302_04864 I302_04764 I302_04764 I302_06024 I302_06024 I302_05978 I302_05978 I302_05917 I302_05917 I302_05851 I302_05851 I302_05777 I302_05777 I302_05775 I302_05775 I302_05763 I302_05763 I302_05749 I302_05749 I302_05715 I302_05715 I302_05569 I302_05569 I302_07011 I302_07011 I302_06982 I302_06982 I302_06971 I302_06971 I302_06804 I302_06804 I302_06779 I302_06779 I302_06634 I302_06634 I302_06511 I302_06511 I302_06483 I302_06483 I302_06414 I302_06414 I302_06379 I302_06379 I302_07635 I302_07635 I302_07597 I302_07597 I302_07548 I302_07548 I302_07502 I302_07502 I302_07500 I302_07500 I302_07205 I302_07205 I302_07115 I302_07115 I302_08348 I302_08348 GUF1 GUF1 I302_08165 I302_08165 I302_08031 I302_08031 I302_07999 I302_07999 I302_07997 I302_07997 I302_07992 I302_07992 I302_07982 I302_07982 I302_07891 I302_07891 I302_07779 I302_07779 I302_08771 I302_08771 I302_08741 I302_08741 I302_08698 I302_08698 I302_08571 I302_08571 I302_08512 I302_08512 I302_08439 I302_08439 I302_08380 I302_08380 I302_09210 I302_09210 I302_09113 I302_09113 I302_09102 I302_09102 I302_09083 I302_09083 I302_09024 I302_09024 I302_08985 I302_08985 I302_08980 I302_08980 I302_08914 I302_08914 I302_08928 I302_08928
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I302_06040CBFD_NFYB_HMF domain-containing protein. (138 aa)
I302_02096Uncharacterized protein. (291 aa)
I302_02190PLK/PLK1 protein kinase. (795 aa)
I302_02212Prefoldin, alpha subunit. (149 aa)
I302_02223General transcriptional repressor. (1152 aa)
I302_02316Uncharacterized protein. (248 aa)
I302_02318Uncharacterized protein. (433 aa)
I302_02345Histone H2A; Belongs to the histone H2A family. (139 aa)
I302_02412ATP-dependent helicase STH1/SNF2. (1584 aa)
I302_02451Uncharacterized protein; Belongs to the actin family. (743 aa)
I302_02591Transcription initiation factor TFIID subunit 9B. (213 aa)
I302_02704RNA polymerase-associated protein LEO1. (528 aa)
I302_02700Multiprotein-bridging factor 1. (129 aa)
I302_02765Uncharacterized protein. (828 aa)
I302_02894TAFII28 domain-containing protein. (243 aa)
I302_03000Peptidyl-prolyl cis-trans isomerase. (182 aa)
I302_03025FACT complex subunit SPT16. (1044 aa)
I302_0313826S protease regulatory subunit 6A-B; Belongs to the AAA ATPase family. (471 aa)
I302_03156Fungal_trans domain-containing protein. (587 aa)
I302_03219Nuclear DNA helicase II. (1606 aa)
I302_03218PAS domain-containing protein. (375 aa)
I302_03254Acid phosphatase. (472 aa)
I302_000455'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1145 aa)
I302_00066Cell differentiation protein rcd1. (475 aa)
I302_00193Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (114 aa)
I302_00188Transcriptional activator HAP5. (271 aa)
I302_00206Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (242 aa)
I302_00207Fork-head domain-containing protein. (343 aa)
I302_00279Uncharacterized protein. (288 aa)
I302_00293Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (97 aa)
I302_00306Uncharacterized protein. (675 aa)
I302_00391Transcription activator snf2l1. (1102 aa)
I302_00421Uncharacterized protein. (1612 aa)
I302_00578Uncharacterized protein. (1586 aa)
I302_00586CMGC/CDK protein kinase. (844 aa)
I302_00587Uncharacterized protein. (194 aa)
I302_00687cAMP-dependent protein kinase regulatory subunit. (505 aa)
I302_00703Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (597 aa)
I302_00707CTD kinase subunit beta. (386 aa)
I302_00727Uncharacterized protein. (374 aa)
I302_00815Histone deacetylase 6/10. (827 aa)
I302_00837ANK_REP_REGION domain-containing protein. (1459 aa)
I302_00934Uncharacterized protein. (841 aa)
I302_00962BHLH domain-containing protein. (436 aa)
I302_00970PITH domain-containing protein. (231 aa)
I302_01074Uncharacterized protein. (342 aa)
I302_01066Uncharacterized protein. (763 aa)
I302_01303Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa)
I302_01460Uncharacterized protein. (252 aa)
I302_01470Ribosome biogenesis ATPase. (797 aa)
I302_01398DNA-directed RNA polymerase II subunit RPB4. (159 aa)
I302_01572Histone deacetylase HOS3. (819 aa)
I302_01622U3 small nucleolar RNA-associated protein 15. (528 aa)
I302_01693ATP-binding cassette, sub-family E, member 1. (603 aa)
I302_01781ATP-dependent RNA helicase prh1. (803 aa)
I302_02097Fungal_trans domain-containing protein. (355 aa)
I302_02094Bromo domain-containing protein. (1579 aa)
I302_02050Cyclin C; Belongs to the cyclin family. (449 aa)
I302_02023BHLH domain-containing protein. (463 aa)
I302_01874FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (584 aa)
I302_04658Peptidase_M50 domain-containing protein. (574 aa)
I302_04581Uncharacterized protein. (1043 aa)
I302_04555RNA polymerase-associated protein RTF1. (549 aa)
I302_04525Uncharacterized protein. (136 aa)
I302_04315Esterase. (782 aa)
I302_04218Co-chaperone. (518 aa)
I302_04227BRCT domain-containing protein. (1312 aa)
I302_04230DNA-directed RNA polymerase II subunit RPB7. (172 aa)
I302_04168Eukaryotic translation initiation factor 5A. (159 aa)
SUS1Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...] (100 aa)
I302_04127Uncharacterized protein. (963 aa)
I302_04057Histone-lysine N-methyltransferase Su(Var)3-9. (474 aa)
I302_03938Beta-lactamase domain-containing protein. (387 aa)
I302_03911Alkylbase DNA N-glycosylase. (775 aa)
I302_03875PAPA-1 domain-containing protein. (401 aa)
I302_03793Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (127 aa)
I302_0374026S protease regulatory subunit 8; Belongs to the AAA ATPase family. (407 aa)
I302_03732Uncharacterized protein. (618 aa)
I302_03698Fungal_trans domain-containing protein. (400 aa)
I302_03647BZIP domain-containing protein. (290 aa)
I302_03671Med12 domain-containing protein. (1701 aa)
I302_03564Zn(2)-C6 fungal-type domain-containing protein. (1155 aa)
I302_03572GATA-type domain-containing protein. (1066 aa)
I302_03506Zn(2)-C6 fungal-type domain-containing protein. (393 aa)
I302_03405Zn(2)-C6 fungal-type domain-containing protein. (691 aa)
I302_0341626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (420 aa)
I302_03388Zn(2)-C6 fungal-type domain-containing protein. (675 aa)
I302_05507Uncharacterized protein. (449 aa)
I302_05429CTD kinase subunit gamma. (282 aa)
MED10Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (190 aa)
I302_05363Uncharacterized protein; Belongs to the MT-A70-like family. (542 aa)
I302_05220JmjC domain-containing protein. (280 aa)
KAE1tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (380 aa)
MED6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (308 aa)
I302_05139Uncharacterized protein. (397 aa)
I302_05073Zn(2)-C6 fungal-type domain-containing protein. (723 aa)
I302_04988Cytoplasmic protein. (510 aa)
I302_04896Uncharacterized protein. (1087 aa)
I302_04865Histone chaperone ASF1. (216 aa)
I302_04864PC4 domain-containing protein. (138 aa)
I302_04764GATA-type domain-containing protein. (567 aa)
I302_06024Uncharacterized protein. (1039 aa)
I302_05978BHLH domain-containing protein. (412 aa)
I302_05917Cellular nucleic acid-binding protein. (189 aa)
I302_05851Fungal specific transcription factor. (1029 aa)
I302_05777CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (360 aa)
I302_05775JmjC domain-containing protein. (461 aa)
I302_05763Uncharacterized protein. (682 aa)
I302_05749Usp domain-containing protein. (728 aa)
I302_05715SAGA-associated factor 29. (342 aa)
I302_05569MADS-box domain-containing protein. (423 aa)
I302_07011Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1133 aa)
I302_06982JmjC domain-containing protein. (410 aa)
I302_06971Abhydrolase_3 domain-containing protein. (351 aa)
I302_06804Uncharacterized protein. (266 aa)
I302_06779Response regulatory domain-containing protein. (1073 aa)
I302_06634Nuclear transcription factor Y subunit beta. (201 aa)
I302_06511Uncharacterized protein. (679 aa)
I302_06483Uncharacterized protein. (231 aa)
I302_06414CBFD_NFYB_HMF domain-containing protein. (168 aa)
I302_06379Transcriptional activator SPT8. (747 aa)
I302_07635Uncharacterized protein. (669 aa)
I302_07597CMGC/CDK/CRK7 protein kinase. (1211 aa)
I302_07548Bromo domain-containing protein. (638 aa)
I302_07502Uncharacterized protein. (270 aa)
I302_07500Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (115 aa)
I302_07205SCA7 domain-containing protein. (449 aa)
I302_07115Forkhead transcription factor 3. (763 aa)
I302_08348Zn(2)-C6 fungal-type domain-containing protein. (736 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (1185 aa)
I302_08165Smg4_UPF3 domain-containing protein. (413 aa)
I302_08031BP28CT domain-containing protein. (2007 aa)
I302_0799940S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (193 aa)
I302_07997Uncharacterized protein. (334 aa)
I302_07992Cellular nucleic acid-binding protein. (199 aa)
I302_07982Parafibromin. (421 aa)
I302_07891PITH domain-containing protein. (217 aa)
I302_07779Transcription initiation factor TFIID subunit 6. (481 aa)
I302_08771Zn(2)-C6 fungal-type domain-containing protein. (733 aa)
I302_08741BHLH domain-containing protein. (1004 aa)
I302_08698Transcription factor. (819 aa)
I302_08571NET1-associated nuclear protein 1 (U3 small nucleolar RNA-associated protein 17). (1090 aa)
I302_08512zf-C2HC5 domain-containing protein. (502 aa)
I302_08439rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (536 aa)
I302_08380Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (555 aa)
I302_09210Uncharacterized protein. (1230 aa)
I302_091133'-5' exonuclease domain-containing protein. (287 aa)
I302_09102Nam9 protein. (354 aa)
I302_09083MADS-box domain-containing protein. (556 aa)
I302_09024Transcription elongation factor SPT6. (1571 aa)
I302_08985Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (858 aa)
I302_0898026S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (414 aa)
I302_08914Uncharacterized protein. (183 aa)
I302_08928Zn(2)-C6 fungal-type domain-containing protein. (466 aa)
Your Current Organism:
Kwoniella bestiolae
NCBI taxonomy Id: 1296100
Other names: Cryptococcus bestiolae CBS 10118, Cryptococcus bestiolae CBS10118, K. bestiolae CBS 10118, Kwoniella bestiolae CBS 10118
Server load: low (26%) [HD]