STRINGSTRING
I302_00045 I302_00045 I302_03354 I302_03354 I302_03251 I302_03251 I302_03156 I302_03156 I302_03149 I302_03149 I302_03148 I302_03148 I302_03103 I302_03103 I302_03033 I302_03033 I302_03032 I302_03032 I302_03025 I302_03025 I302_02992 I302_02992 I302_02977 I302_02977 I302_02975 I302_02975 I302_02963 I302_02963 I302_02930 I302_02930 I302_02943 I302_02943 I302_02920 I302_02920 I302_02924 I302_02924 I302_02923 I302_02923 I302_01660 I302_01660 I302_01686 I302_01686 I302_01792 I302_01792 I302_01785 I302_01785 I302_01766 I302_01766 I302_08877 I302_08877 I302_08905 I302_08905 I302_08912 I302_08912 I302_08928 I302_08928 I302_08978 I302_08978 I302_08979 I302_08979 I302_09024 I302_09024 I302_09053 I302_09053 I302_09069 I302_09069 I302_09168 I302_09168 BNA1 BNA1 I302_09175 I302_09175 I302_08433 I302_08433 I302_08439 I302_08439 I302_08440 I302_08440 I302_08585 I302_08585 I302_08587 I302_08587 I302_08648 I302_08648 I302_08703 I302_08703 I302_08697 I302_08697 I302_08710 I302_08710 I302_08721 I302_08721 I302_08746 I302_08746 I302_08749 I302_08749 I302_08773 I302_08773 I302_08771 I302_08771 I302_07729 I302_07729 I302_07751 I302_07751 I302_07761 I302_07761 I302_07779 I302_07779 I302_07783 I302_07783 I302_07845 I302_07845 I302_07860 I302_07860 I302_07978 I302_07978 I302_07982 I302_07982 I302_08000 I302_08000 I302_07993 I302_07993 I302_08035 I302_08035 I302_08062 I302_08062 I302_08079 I302_08079 I302_08094 I302_08094 I302_08097 I302_08097 I302_08111 I302_08111 I302_08148 I302_08148 I302_08151 I302_08151 I302_08153 I302_08153 I302_08164 I302_08164 I302_08175 I302_08175 I302_08187 I302_08187 I302_08224 I302_08224 I302_08233 I302_08233 I302_08291 I302_08291 I302_08298 I302_08298 I302_08309 I302_08309 I302_08341 I302_08341 I302_08329 I302_08329 I302_07100 I302_07100 I302_07095 I302_07095 I302_07116 I302_07116 I302_07174 I302_07174 I302_07195 I302_07195 I302_07209 I302_07209 I302_07231 I302_07231 I302_07257 I302_07257 I302_07275 I302_07275 I302_07280 I302_07280 I302_07315 I302_07315 I302_07389 I302_07389 I302_07406 I302_07406 I302_07391 I302_07391 I302_07410 I302_07410 I302_07438 I302_07438 I302_07534 I302_07534 I302_07573 I302_07573 I302_07601 I302_07601 I302_07597 I302_07597 I302_06359 I302_06359 I302_06388 I302_06388 I302_06386 I302_06386 I302_06414 I302_06414 I302_06458 I302_06458 I302_06457 I302_06457 I302_06476 I302_06476 I302_06564 I302_06564 I302_06563 I302_06563 I302_06622 I302_06622 I302_06642 I302_06642 I302_06650 I302_06650 I302_06674 I302_06674 I302_06700 I302_06700 I302_06697 I302_06697 I302_06753 I302_06753 I302_06754 I302_06754 I302_06796 I302_06796 I302_06785 I302_06785 I302_06812 I302_06812 I302_06901 I302_06901 I302_06906 I302_06906 I302_05630 I302_05630 I302_05662 I302_05662 I302_05696 I302_05696 I302_05736 I302_05736 I302_05740 I302_05740 I302_05777 I302_05777 I302_05814 I302_05814 I302_05810 I302_05810 I302_05836 I302_05836 I302_05843 I302_05843 I302_05848 I302_05848 I302_05851 I302_05851 I302_05864 I302_05864 I302_05866 I302_05866 I302_05867 I302_05867 I302_05865 I302_05865 I302_06040 I302_06040 I302_06046 I302_06046 I302_06042 I302_06042 I302_06051 I302_06051 I302_06075 I302_06075 I302_06092 I302_06092 I302_06133 I302_06133 I302_06154 I302_06154 I302_06177 I302_06177 I302_06257 I302_06257 I302_06269 I302_06269 I302_04696 I302_04696 I302_04743 I302_04743 I302_04993 I302_04993 I302_05022 I302_05022 I302_05043 I302_05043 I302_05062 I302_05062 I302_05077 I302_05077 I302_05081 I302_05081 I302_05139 I302_05139 I302_05130 I302_05130 I302_05248 I302_05248 I302_05273 I302_05273 I302_05399 I302_05399 I302_05434 I302_05434 I302_05412 I302_05412 I302_05486 I302_05486 I302_03377 I302_03377 I302_03383 I302_03383 I302_03401 I302_03401 I302_03644 I302_03644 I302_03654 I302_03654 I302_03645 I302_03645 I302_03655 I302_03655 I302_03675 I302_03675 I302_03756 I302_03756 I302_03791 I302_03791 I302_03757 I302_03757 I302_03793 I302_03793 I302_03810 I302_03810 I302_03853 I302_03853 I302_03920 I302_03920 I302_03943 I302_03943 I302_04026 I302_04026 I302_04077 I302_04077 I302_04107 I302_04107 I302_04148 I302_04148 I302_04181 I302_04181 SUS1 SUS1 I302_04163 I302_04163 I302_04230 I302_04230 I302_04199 I302_04199 I302_04224 I302_04224 I302_04249 I302_04249 I302_04294 I302_04294 I302_04362 I302_04362 I302_04416 I302_04416 I302_04414 I302_04414 I302_04420 I302_04420 I302_04418 I302_04418 I302_04431 I302_04431 I302_04417 I302_04417 I302_04441 I302_04441 I302_04555 I302_04555 I302_04530 I302_04530 I302_04540 I302_04540 I302_04589 I302_04589 I302_04601 I302_04601 I302_04682 I302_04682 I302_01929 I302_01929 I302_02031 I302_02031 I302_02049 I302_02049 I302_02097 I302_02097 I302_02096 I302_02096 I302_02148 I302_02148 I302_02218 I302_02218 I302_02211 I302_02211 ADK1 ADK1 I302_02369 I302_02369 I302_02382 I302_02382 I302_02439 I302_02439 I302_02488 I302_02488 I302_02473 I302_02473 I302_02591 I302_02591 I302_02626 I302_02626 I302_02616 I302_02616 I302_02704 I302_02704 I302_02705 I302_02705 I302_02690 I302_02690 I302_02679 I302_02679 I302_02755 I302_02755 I302_02771 I302_02771 I302_02789 I302_02789 BNA5 BNA5 I302_02796 I302_02796 I302_02798 I302_02798 I302_02812 I302_02812 BNA4 BNA4 I302_02839 I302_02839 I302_02833 I302_02833 I302_02840 I302_02840 I302_02888 I302_02888 I302_02894 I302_02894 I302_01600 I302_01600 I302_01701 I302_01701 I302_01655 I302_01655 I302_01573 I302_01573 I302_01542 I302_01542 I302_01398 I302_01398 I302_01460 I302_01460 I302_01459 I302_01459 I302_01441 I302_01441 I302_01466 I302_01466 I302_01435 I302_01435 I302_01402 I302_01402 I302_01417 I302_01417 I302_01337 I302_01337 I302_01303 I302_01303 I302_01169 I302_01169 I302_01171 I302_01171 I302_01066 I302_01066 I302_01056 I302_01056 I302_01023 I302_01023 I302_01019 I302_01019 I302_00934 I302_00934 I302_00922 I302_00922 I302_00931 I302_00931 I302_00877 I302_00877 I302_00859 I302_00859 I302_00764 I302_00764 I302_00691 I302_00691 I302_00684 I302_00684 I302_00640 I302_00640 I302_00587 I302_00587 I302_00586 I302_00586 I302_00571 I302_00571 I302_00516 I302_00516 I302_00505 I302_00505 I302_00445 I302_00445 I302_00410 I302_00410 I302_00391 I302_00391 I302_00399 I302_00399 I302_00288 I302_00288 I302_00280 I302_00280 I302_00253 I302_00253 I302_00238 I302_00238 I302_00233 I302_00233 I302_00211 I302_00211 I302_00206 I302_00206 I302_00168 I302_00168 I302_00138 I302_00138 I302_00099 I302_00099 I302_00107 I302_00107 I302_00125 I302_00125 I302_00106 I302_00106
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I302_000455'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1145 aa)
I302_03354Uncharacterized protein. (689 aa)
I302_03251Carbamoyl-phosphate synthase arginine-specific large chain. (1159 aa)
I302_03156Fungal_trans domain-containing protein. (587 aa)
I302_03149dUTP pyrophosphatase. (176 aa)
I302_03148DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (710 aa)
I302_03103Uncharacterized protein. (985 aa)
I302_03033Uncharacterized protein. (316 aa)
I302_03032AMP deaminase. (868 aa)
I302_03025FACT complex subunit SPT16. (1044 aa)
I302_02992Uncharacterized protein. (470 aa)
I302_02977BTB domain-containing protein. (1137 aa)
I302_02975Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (161 aa)
I302_02963Pantothenate kinase. (523 aa)
I302_02930Thymidylate kinase. (219 aa)
I302_02943Tryptophan 2,3-dioxygenase. (568 aa)
I302_02920Amidophosphoribosyltransferase. (572 aa)
I302_02924NADH kinase. (396 aa)
I302_02923Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (430 aa)
I302_01660DNA-directed RNA polymerase I, II, and III subunit RPABC1. (200 aa)
I302_01686Isochorismatase domain-containing protein. (230 aa)
I302_01792Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (608 aa)
I302_01785UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (397 aa)
I302_01766Acetyl-coenzyme A synthetase. (678 aa)
I302_08877Fungal_trans domain-containing protein. (1019 aa)
I302_08905DNA polymerase. (1981 aa)
I302_08912Uncharacterized protein. (553 aa)
I302_08928Zn(2)-C6 fungal-type domain-containing protein. (466 aa)
I302_08978BRCT domain-containing protein. (293 aa)
I302_08979Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (173 aa)
I302_09024Transcription elongation factor SPT6. (1571 aa)
I302_09053ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (173 aa)
I302_09069Uncharacterized protein. (2085 aa)
I302_09168GDP-mannose 4,6-dehydratase. (566 aa)
BNA13-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (175 aa)
I302_09175Fungal_trans domain-containing protein. (608 aa)
I302_08433DNA-directed RNA polymerase II subunit RPB11. (160 aa)
I302_08439rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (536 aa)
I302_08440CTP_transf_like domain-containing protein. (374 aa)
I302_08585Uncharacterized protein. (433 aa)
I302_08587DNA-directed RNA polymerase I and III subunit RPAC2. (161 aa)
I302_08648dCMP deaminase. (363 aa)
I302_08703DNA-directed RNA polymerase I, II, and III subunit rpabc5. (69 aa)
I302_08697RPOL4c domain-containing protein. (240 aa)
I302_08710DNA polymerase delta subunit 2. (502 aa)
I302_08721RNA polymerase-associated protein CTR9. (1183 aa)
I302_08746DNA polymerase gamma 1. (1454 aa)
I302_08749F-type H+-transporting ATPase subunit delta. (169 aa)
I302_08773Serine-tRNA ligase. (527 aa)
I302_08771Zn(2)-C6 fungal-type domain-containing protein. (733 aa)
I302_07729Ribonucleoside-diphosphate reductase subunit M2. (446 aa)
I302_07751Transferase. (219 aa)
I302_07761DNA-directed RNA polymerase III subunit RPC4. (517 aa)
I302_07779Transcription initiation factor TFIID subunit 6. (481 aa)
I302_07783ATP synthase subunit gamma. (289 aa)
I302_07845Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family. (561 aa)
I302_07860Uncharacterized protein. (306 aa)
I302_07978Uracil phosphoribosyltransferase. (233 aa)
I302_07982Parafibromin. (421 aa)
I302_08000Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1042 aa)
I302_07993Uracil phosphoribosyltransferase. (233 aa)
I302_08035DNA-directed RNA polymerase I, II, and III subunit RPABC2. (176 aa)
I302_08062N-acetyltransferase domain-containing protein. (204 aa)
I302_08079Nuclear protein. (1031 aa)
I302_08094Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (278 aa)
I302_08097Uncharacterized protein. (718 aa)
I302_08111V-type proton ATPase catalytic subunit A. (614 aa)
I302_08148Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (479 aa)
I302_08151Transcription initiation factor TFIID subunit 2. (1800 aa)
I302_08153Glutaryl-CoA dehydrogenase. (427 aa)
I302_08164Dihydrodipicolinate synthetase; Belongs to the DapA family. (342 aa)
I302_08175Uncharacterized protein. (90 aa)
I302_08187DNA primase; Belongs to the eukaryotic-type primase small subunit family. (432 aa)
I302_08224Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (584 aa)
I302_08233Nucleoside diphosphate kinase. (152 aa)
I302_08291Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (275 aa)
I302_08298Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (399 aa)
I302_08309UDP-glucose 6-dehydrogenase. (468 aa)
I302_08341Uncharacterized protein. (208 aa)
I302_08329Beta-lactamase domain-containing protein. (606 aa)
I302_07100Uncharacterized protein. (380 aa)
I302_07095Beta-lactamase domain-containing protein. (506 aa)
I302_07116Transcription initiation factor TFIIE subunit beta. (311 aa)
I302_07174Adenylate cyclase. (2346 aa)
I302_07195Orotate phosphoribosyltransferase. (222 aa)
I302_07209TFIID_20kDa domain-containing protein. (618 aa)
I302_07231General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (447 aa)
I302_07257Cyclin H; Belongs to the cyclin family. (452 aa)
I302_07275Nicotinamide riboside kinase. (262 aa)
I302_07280BRCT domain-containing protein. (875 aa)
I302_07315Dihydrodipicolinate synthase; Belongs to the DapA family. (334 aa)
I302_07389Telomere_reg-2 domain-containing protein. (1105 aa)
I302_07406DNA ligase. (816 aa)
I302_07391NAD+ kinase. (1161 aa)
I302_07410BTB domain-containing protein. (589 aa)
I302_07438DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (143 aa)
I302_07534Phosphoribosylformylglycinamidine synthase. (1356 aa)
I302_07573Uncharacterized protein. (846 aa)
I302_07601Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (869 aa)
I302_07597CMGC/CDK/CRK7 protein kinase. (1211 aa)
I302_06359Uncharacterized protein. (348 aa)
I302_06388DNA-directed RNA polymerase II subunit RPB3. (389 aa)
I302_06386RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (571 aa)
I302_06414CBFD_NFYB_HMF domain-containing protein. (168 aa)
I302_06458Carbamoyl-phosphate synthase, large subunit. (2269 aa)
I302_06457TATA-binding protein-associated factor. (1882 aa)
I302_06476Zn(2)-C6 fungal-type domain-containing protein. (1124 aa)
I302_06564DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1800 aa)
I302_06563DNA polymerase eta subunit. (705 aa)
I302_06622Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (856 aa)
I302_06642Phosphopantothenate-cysteine ligase. (371 aa)
I302_06650RNA polymerase II-associated factor 1. (451 aa)
I302_06674UDP-glucuronate decarboxylase. (410 aa)
I302_06700RNA-dependent RNA polymerase. (1123 aa)
I302_06697Ribose-phosphate pyrophosphokinase. (324 aa)
I302_06753Beta-lactamase domain-containing protein. (591 aa)
I302_06754Beta-lactamase domain-containing protein. (635 aa)
I302_06796DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (122 aa)
I302_06785Pyruvate dehydrogenase X component. (352 aa)
I302_06812Uncharacterized protein. (1422 aa)
I302_06901Uridine kinase; Belongs to the uridine kinase family. (578 aa)
I302_06906TFIIS central domain-containing protein. (830 aa)
I302_05630Uncharacterized protein. (561 aa)
I302_05662Phosphoribosylamine-glycine ligase. (807 aa)
I302_05696Mitotic spindle assembly checkpoint protein MAD2B. (241 aa)
I302_05736DNA repair protein RAD50. (1357 aa)
I302_05740Transcription initiation factor TFIIA large subunit. (195 aa)
I302_05777CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (360 aa)
I302_05814TFIIIC_sub6 domain-containing protein. (337 aa)
I302_05810Probable acetate kinase. (434 aa)
I302_05836CID domain-containing protein. (699 aa)
I302_05843Replication factor A2. (256 aa)
I302_05848TFIID_20kDa domain-containing protein. (1150 aa)
I302_05851Fungal specific transcription factor. (1029 aa)
I302_05864RNA polymerase I-specific transcription initiation factor RRN3. (886 aa)
I302_05866RNase III domain-containing protein. (320 aa)
I302_05867RNase III domain-containing protein. (471 aa)
I302_05865RNase III domain-containing protein. (430 aa)
I302_06040CBFD_NFYB_HMF domain-containing protein. (138 aa)
I302_06046DNA-directed RNA polymerase I and III subunit RPAC1. (345 aa)
I302_06042Glutamine-fructose-6-phosphate transaminase (Isomerizing). (711 aa)
I302_06051ATP synthase F1, delta subunit. (206 aa)
I302_06075DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1244 aa)
I302_06092DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1736 aa)
I302_06133Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (612 aa)
I302_06154RNA polymerase II subunit A domain phosphatase SSU72. (350 aa)
I302_06177Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (454 aa)
I302_06257Uncharacterized protein. (1795 aa)
I302_06269Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (467 aa)
I302_04696Fungal_trans domain-containing protein. (551 aa)
I302_04743Uncharacterized protein. (219 aa)
I302_04993Uncharacterized protein. (457 aa)
I302_05022Uncharacterized protein. (837 aa)
I302_05043S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (309 aa)
I302_05062DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1310 aa)
I302_05077CID domain-containing protein. (701 aa)
I302_05081Phosphopantothenoylcysteine decarboxylase. (370 aa)
I302_05139Uncharacterized protein. (397 aa)
I302_05130SANT domain-containing protein. (889 aa)
I302_05248DNA polymerase kappa subunit. (628 aa)
I302_05273DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (570 aa)
I302_05399Transcription initiation factor TFIIH subunit 1. (650 aa)
I302_05434Uncharacterized protein. (169 aa)
I302_05412DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (123 aa)
I302_05486DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1216 aa)
I302_03377Fungal_trans domain-containing protein. (596 aa)
I302_03383Uncharacterized protein. (269 aa)
I302_03401Uncharacterized protein. (240 aa)
I302_03644DNA-directed RNA polymerase III subunit RPC8. (245 aa)
I302_03654Uncharacterized protein. (606 aa)
I302_03645Mannose-6-phosphate isomerase, class I. (452 aa)
I302_03655DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (509 aa)
I302_03675Thymidylate synthase. (331 aa)
I302_03756Uncharacterized protein. (1027 aa)
I302_03791COP9 signalosome complex subunit 12. (403 aa)
I302_03757ATP-citrate synthase subunit 1. (1149 aa)
I302_03793Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (127 aa)
I302_03810DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (971 aa)
I302_03853Nucleoside-diphosphate kinase; Belongs to the NDK family. (222 aa)
I302_03920Uncharacterized protein. (83 aa)
I302_03943Adenylate kinase; Belongs to the adenylate kinase family. (419 aa)
I302_04026F-type H+-transporting ATPase subunit H. (126 aa)
I302_04077DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1351 aa)
I302_04107Zn(2)-C6 fungal-type domain-containing protein. (849 aa)
I302_04148Serine-tRNA ligase. (458 aa)
I302_04181Uncharacterized protein. (263 aa)
SUS1Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...] (100 aa)
I302_04163Exosome complex component RRP41. (258 aa)
I302_04230DNA-directed RNA polymerase II subunit RPB7. (172 aa)
I302_04199Adenine phosphoribosyltransferase. (178 aa)
I302_04224DNA-directed RNA polymerase I, II, and III subunit RPABC4. (84 aa)
I302_04249Adenosine kinase. (355 aa)
I302_04294DNA polymerase. (1500 aa)
I302_04362Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (413 aa)
I302_04416RNase III domain-containing protein. (305 aa)
I302_04414DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (542 aa)
I302_04420Uncharacterized protein. (579 aa)
I302_04418RNase III domain-containing protein. (289 aa)
I302_04431DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1200 aa)
I302_04417RNase III domain-containing protein. (387 aa)
I302_04441Uncharacterized protein. (790 aa)
I302_04555RNA polymerase-associated protein RTF1. (549 aa)
I302_04530Uncharacterized protein; Belongs to the DapA family. (340 aa)
I302_04540Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (186 aa)
I302_04589Uncharacterized protein. (1065 aa)
I302_04601Uncharacterized protein. (83 aa)
I302_04682ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (552 aa)
I302_01929Uncharacterized protein. (77 aa)
I302_02031DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (476 aa)
I302_02049Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (556 aa)
I302_02097Fungal_trans domain-containing protein. (355 aa)
I302_02096Uncharacterized protein. (291 aa)
I302_02148Transcription initiation protein SPT3. (414 aa)
I302_02218Ribonucleoside-diphosphate reductase small subunit. (399 aa)
I302_02211Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (712 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (279 aa)
I302_02369FMN adenylyltransferase. (302 aa)
I302_02382Epimerase domain-containing protein. (343 aa)
I302_02439RNase III domain-containing protein. (495 aa)
I302_02488DNA ligase. (1084 aa)
I302_02473DNA polymerase. (1063 aa)
I302_02591Transcription initiation factor TFIID subunit 9B. (213 aa)
I302_02626DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2243 aa)
I302_02616RPA43_OB domain-containing protein. (376 aa)
I302_02704RNA polymerase-associated protein LEO1. (528 aa)
I302_02705F-type H+-transporting ATPase subunit B. (229 aa)
I302_02690Guanylate kinase. (220 aa)
I302_02679GMP synthase [glutamine-hydrolyzing]. (549 aa)
I302_02755Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (266 aa)
I302_02771Ribose-phosphate pyrophosphokinase. (320 aa)
I302_02789F-type H+-transporting ATPase subunit J. (60 aa)
BNA5Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (465 aa)
I302_02796Dihydrodipicolinate synthetase. (362 aa)
I302_02798Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (282 aa)
I302_02812Transcription initiation factor TFIID subunit 1. (1032 aa)
BNA4Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (491 aa)
I302_02839Phosphoribosylglycinamide formyltransferase. (302 aa)
I302_02833Dephospho-CoA kinase. (286 aa)
I302_02840Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (625 aa)
I302_02888Transcription initiation factor TFIIE subunit alpha. (464 aa)
I302_02894TAFII28 domain-containing protein. (243 aa)
I302_01600DNA excision repair protein ERCC-3. (876 aa)
I302_01701Dihydroorotase, homodimeric type. (357 aa)
I302_01655TAFII55_N domain-containing protein. (754 aa)
I302_01573Uncharacterized protein. (769 aa)
I302_01542DNA-directed RNA polymerase III subunit RPC5. (375 aa)
I302_01398DNA-directed RNA polymerase II subunit RPB4. (159 aa)
I302_01460Uncharacterized protein. (252 aa)
I302_01459Mannose-1-phosphate guanyltransferase. (299 aa)
I302_01441DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (139 aa)
I302_01466Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1156 aa)
I302_01435SWIB domain-containing protein. (300 aa)
I302_01402Mannose-6-phosphate isomerase. (435 aa)
I302_01417Uncharacterized protein. (890 aa)
I302_01337Uncharacterized protein. (433 aa)
I302_01303Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa)
I302_01169CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (631 aa)
I302_01171Uncharacterized protein. (472 aa)
I302_01066Uncharacterized protein. (763 aa)
I302_01056Riboflavin kinase. (251 aa)
I302_01023F-type H+-transporting ATPase subunit G. (162 aa)
I302_01019Peptide chain release factor 1. (445 aa)
I302_00934Uncharacterized protein. (841 aa)
I302_00922Uncharacterized protein. (496 aa)
I302_00931Transcription initiation factor TFIID subunit 5. (890 aa)
I302_00877BAH domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (920 aa)
I302_00859RNA-dependent RNA polymerase. (1405 aa)
I302_00764DNA polymerase phi subunit. (1224 aa)
I302_00691DNA ligase 1. (1010 aa)
I302_00684DNA excision repair protein ERCC-2. (811 aa)
I302_00640Endoribonuclease YSH1. (756 aa)
I302_00587Uncharacterized protein. (194 aa)
I302_00586CMGC/CDK protein kinase. (844 aa)
I302_00571Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (196 aa)
I302_00516Uncharacterized protein. (622 aa)
I302_00505Zn(2)-C6 fungal-type domain-containing protein. (969 aa)
I302_00445TATA-box-binding protein. (231 aa)
I302_00410Uncharacterized protein. (192 aa)
I302_00391Transcription activator snf2l1. (1102 aa)
I302_00399Senataxin. (2145 aa)
I302_00288NmrA domain-containing protein. (325 aa)
I302_00280Beta-lactamase domain-containing protein. (585 aa)
I302_00253UDP-N-acetylglucosamine pyrophosphorylase. (540 aa)
I302_00238Uncharacterized protein. (1234 aa)
I302_00233Transcription initiation factor TFIIB. (414 aa)
I302_00211Transcription elongation factor S-II. (336 aa)
I302_00206Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (242 aa)
I302_00168Acetyl-CoA carboxylase/biotin carboxylase. (2234 aa)
I302_00138ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (548 aa)
I302_00099Nicotinate (Nicotinamide) nucleotide adenylyltransferase. (578 aa)
I302_00107Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (296 aa)
I302_00125TFIIB-type domain-containing protein. (712 aa)
I302_00106DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1452 aa)
Your Current Organism:
Kwoniella bestiolae
NCBI taxonomy Id: 1296100
Other names: Cryptococcus bestiolae CBS 10118, Cryptococcus bestiolae CBS10118, K. bestiolae CBS 10118, Kwoniella bestiolae CBS 10118
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