STRINGSTRING
I302_00585 I302_00585 I302_08888 I302_08888 I302_09066 I302_09066 I302_09065 I302_09065 I302_08342 I302_08342 I302_07175 I302_07175 COQ6 COQ6 I302_06374 I302_06374 I302_06739 I302_06739 I302_06920 I302_06920 I302_05800 I302_05800 COQ5 COQ5 COQ3 COQ3 COQ7 COQ7 I302_04392 I302_04392 I302_00626 I302_00626 I302_01286 I302_01286 I302_01289 I302_01289 I302_01533 I302_01533 I302_01732 I302_01732
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I302_00585Mitochondrial protein. (353 aa)
I302_08888Aromatic amino acid aminotransferase I. (574 aa)
I302_09066NAD(P)H:quinone oxidoreductase, type IV. (213 aa)
I302_09065NAD(P)H:quinone oxidoreductase, type IV. (304 aa)
I302_08342Uncharacterized protein. (330 aa)
I302_07175Uncharacterized protein. (230 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (620 aa)
I302_06374Methyltransf_25 domain-containing protein. (299 aa)
I302_06739DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (310 aa)
I302_069204HBT domain-containing protein. (176 aa)
I302_05800Uncharacterized protein. (2003 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (336 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (354 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (250 aa)
I302_04392Tyrosine aminotransferase. (436 aa)
I302_006264-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (451 aa)
I302_01286Uncharacterized protein. (280 aa)
I302_01289Uncharacterized protein. (330 aa)
I302_015334HBT domain-containing protein. (190 aa)
I302_01732Aminotran_1_2 domain-containing protein. (541 aa)
Your Current Organism:
Kwoniella bestiolae
NCBI taxonomy Id: 1296100
Other names: Cryptococcus bestiolae CBS 10118, Cryptococcus bestiolae CBS10118, K. bestiolae CBS 10118, Kwoniella bestiolae CBS 10118
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