60 items (Kwoniella bestiolae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I302_05515	Uncharacterized protein. (118 aa)
	I302_08923	Chaperonin GroES; Belongs to the GroES chaperonin family. (105 aa)
	I302_09091	Guanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. (717 aa)
	I302_09163	Uncharacterized protein. (243 aa)
	I302_09200	Endoribonuclease L-PSP. (130 aa)
	I302_08524	Nudix hydrolase domain-containing protein. (190 aa)
	I302_08591	Malonic semialdehyde reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
	I302_08648	dCMP deaminase. (363 aa)
	I302_08768	Uncharacterized protein. (137 aa)
	I302_07729	Ribonucleoside-diphosphate reductase subunit M2. (446 aa)
	I302_07924	MFS domain-containing protein. (492 aa)
	I302_07978	Uracil phosphoribosyltransferase. (233 aa)
	I302_07993	Uracil phosphoribosyltransferase. (233 aa)
	I302_08233	Nucleoside diphosphate kinase. (152 aa)
	I302_08264	Cytoplasmic protein. (486 aa)
	I302_08291	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (275 aa)
	I302_08314	Importin N-terminal domain-containing protein. (1038 aa)
	I302_08336	MFS domain-containing protein. (528 aa)
	I302_07195	Orotate phosphoribosyltransferase. (222 aa)
	I302_07637	Endoribonuclease. (129 aa)
	I302_06368	Uncharacterized protein. (121 aa)
	I302_06403	Hydrolase. (410 aa)
	I302_06458	Carbamoyl-phosphate synthase, large subunit. (2269 aa)
	I302_06508	Uncharacterized protein. (526 aa)
	I302_06582	MFS domain-containing protein. (576 aa)
	I302_06622	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (856 aa)
	I302_06901	Uridine kinase; Belongs to the uridine kinase family. (578 aa)
	I302_05830	Vacuolar protein. (607 aa)
	I302_05994	Uncharacterized protein. (113 aa)
	I302_04715	Dihydropyrimidinase. (500 aa)
	I302_04888	5'/3'-nucleotidase SurE. (387 aa)
	I302_03399	Malonic semialdehyde reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (286 aa)
	I302_03654	Uncharacterized protein. (606 aa)
	I302_03675	Thymidylate synthase. (331 aa)
	I302_03764	TLC domain-containing protein. (304 aa)
	I302_03853	Nucleoside-diphosphate kinase; Belongs to the NDK family. (222 aa)
	I302_04016	Carbamoyl-phosphate synthase, small subunit. (450 aa)
	I302_04107	Zn(2)-C6 fungal-type domain-containing protein. (849 aa)
	I302_04226	HD domain-containing protein. (268 aa)
	I302_04310	Membrane transporter. (683 aa)
	I302_04447	Uncharacterized protein. (786 aa)
	I302_04468	Uncharacterized protein. (935 aa)
	I302_01909	Uncharacterized protein. (119 aa)
	I302_02218	Ribonucleoside-diphosphate reductase small subunit. (399 aa)
	I302_02245	Uncharacterized protein. (482 aa)
	I302_02688	MFS domain-containing protein. (573 aa)
	I302_02840	Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (625 aa)
	I302_02930	Thymidylate kinase. (219 aa)
	I302_02975	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (161 aa)
	I302_02976	Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (396 aa)
	I302_03149	dUTP pyrophosphatase. (176 aa)
	I302_03251	Carbamoyl-phosphate synthase arginine-specific large chain. (1159 aa)
	I302_00107	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (296 aa)
	I302_00134	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (868 aa)
	I302_00239	Endoribonuclease. (129 aa)
	I302_00520	Uncharacterized protein. (193 aa)
	I302_00516	Uncharacterized protein. (622 aa)
	I302_00563	Indigoidine synthase A family protein. (797 aa)
	I302_01169	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (631 aa)
	I302_01701	Dihydroorotase, homodimeric type. (357 aa)

Your Current Organism:

Kwoniella bestiolae

NCBI taxonomy Id: 1296100
Other names: Cryptococcus bestiolae CBS 10118, Cryptococcus bestiolae CBS10118, K. bestiolae CBS 10118, Kwoniella bestiolae CBS 10118

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I302_00107	I302_00134	A0A1B9GC87	A0A1B9GCA9	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.	0.785
I302_00107	I302_00516	A0A1B9GC87	A0A1B9GDD4	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.725
I302_00107	I302_00520	A0A1B9GC87	A0A1B9GDD1	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.517
I302_00107	I302_01169	A0A1B9GC87	A0A1B9GF85	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.878
I302_00107	I302_01701	A0A1B9GC87	A0A1B9GGI5	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Dihydroorotase, homodimeric type.	0.562
I302_00107	I302_02245	A0A1B9GC87	A0A1B9G8R6	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.639
I302_00107	I302_02840	A0A1B9GC87	A0A1B9GAE7	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.	0.416
I302_00107	I302_02930	A0A1B9GC87	A0A1B9GAP3	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Thymidylate kinase.	0.911
I302_00107	I302_02975	A0A1B9GC87	A0A1B9GAS4	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.	0.624
I302_00107	I302_02976	A0A1B9GC87	A0A1B9GAT8	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.	0.664
I302_00107	I302_03149	A0A1B9GC87	A0A1B9GBA0	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	dUTP pyrophosphatase.	0.725
I302_00107	I302_03654	A0A1B9GC87	A0A1B9G4K7	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.678
I302_00107	I302_03675	A0A1B9GC87	A0A1B9G4S9	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Thymidylate synthase.	0.657
I302_00107	I302_03764	A0A1B9GC87	A0A1B9G4X1	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	TLC domain-containing protein.	0.424
I302_00107	I302_03853	A0A1B9GC87	A0A1B9G574	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Nucleoside-diphosphate kinase; Belongs to the NDK family.	0.793
I302_00107	I302_04107	A0A1B9GC87	A0A1B9G5Z1	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Zn(2)-C6 fungal-type domain-containing protein.	0.733
I302_00107	I302_04447	A0A1B9GC87	A0A1B9G6U8	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.788
I302_00107	I302_05830	A0A1B9GC87	A0A1B9G029	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Vacuolar protein.	0.637
I302_00107	I302_05994	A0A1B9GC87	A0A1B9G0I3	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.585
I302_00107	I302_06508	A0A1B9GC87	A0A1B9FXN4	Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Uncharacterized protein.	0.639