(23 nodes) Glycosylphosphatidylinositol (GPI)-anchor biosynthesis network (Kwoniella bestiolae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	I302_00082	Phosphatidylinositol glycan, class S. (666 aa)
	I302_02951	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (291 aa)
	I302_02713	Pre-rRNA-processing protein TSR2. (215 aa)
	I302_02337	Mannosyltransferase. (616 aa)
	I302_04554	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (406 aa)
	I302_04388	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (742 aa)
	I302_04214	Phosphatidylinositol glycan, class P. (182 aa)
	I302_03818	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (96 aa)
	I302_05432	Glycosylphosphatidylinositol transamidase. (552 aa)
	I302_05223	Uncharacterized protein. (441 aa)
	I302_06222	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (728 aa)
	I302_06949	Uncharacterized protein. (231 aa)
	I302_06876	Uncharacterized protein. (560 aa)
	I302_07515	Uncharacterized protein. (604 aa)
	I302_08937	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity. (437 aa)
	I302_01414	Uncharacterized protein. (289 aa)
	I302_01128	Uncharacterized protein. (272 aa)
	I302_01015	Mannosyltransferase. (508 aa)
	I302_00937	Uncharacterized protein. (541 aa)
	I302_00660	Phosphatidylinositol glycan, class O. (1069 aa)
	I302_00354	Phosphatidylinositol glycan, class C. (374 aa)
	I302_00244	Uncharacterized protein. (162 aa)
	I302_00090	Uncharacterized protein. (371 aa)

Your Current Organism:

Kwoniella bestiolae

NCBI taxonomy Id: 1296100
Other names: Cryptococcus bestiolae CBS 10118, Cryptococcus bestiolae CBS10118, K. bestiolae CBS 10118, Kwoniella bestiolae CBS 10118

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I302_00082	I302_00354	A0A1B9GC52	A0A1B9GCW9	Phosphatidylinositol glycan, class S.	Phosphatidylinositol glycan, class C.	0.434
I302_00082	I302_00660	A0A1B9GC52	A0A1B9GDT1	Phosphatidylinositol glycan, class S.	Phosphatidylinositol glycan, class O.	0.887
I302_00082	I302_01414	A0A1B9GC52	A0A1B9GG17	Phosphatidylinositol glycan, class S.	Uncharacterized protein.	0.816
I302_00082	I302_02337	A0A1B9GC52	A0A1B9G8X7	Phosphatidylinositol glycan, class S.	Mannosyltransferase.	0.507
I302_00082	I302_04388	A0A1B9GC52	A0A1B9G6S8	Phosphatidylinositol glycan, class S.	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.	0.880
I302_00082	I302_04554	A0A1B9GC52	A0A1B9G753	Phosphatidylinositol glycan, class S.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.998
I302_00082	I302_05223	A0A1B9GC52	A0A1B9G304	Phosphatidylinositol glycan, class S.	Uncharacterized protein.	0.993
I302_00082	I302_05432	A0A1B9GC52	A0A1B9G3P6	Phosphatidylinositol glycan, class S.	Glycosylphosphatidylinositol transamidase.	0.998
I302_00082	I302_06876	A0A1B9GC52	A0A1B9FYQ7	Phosphatidylinositol glycan, class S.	Uncharacterized protein.	0.998
I302_00082	I302_08937	A0A1B9GC52	A0A1B9FR72	Phosphatidylinositol glycan, class S.	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity.	0.448
I302_00090	I302_04554	A0A1B9GC55	A0A1B9G753	Uncharacterized protein.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.577
I302_00244	I302_00354	A0A1B9GCK3	A0A1B9GCW9	Uncharacterized protein.	Phosphatidylinositol glycan, class C.	0.913
I302_00244	I302_00660	A0A1B9GCK3	A0A1B9GDT1	Uncharacterized protein.	Phosphatidylinositol glycan, class O.	0.557
I302_00244	I302_00937	A0A1B9GCK3	A0A1B9GED6	Uncharacterized protein.	Uncharacterized protein.	0.911
I302_00244	I302_01015	A0A1B9GCK3	A0A1B9GEW4	Uncharacterized protein.	Mannosyltransferase.	0.507
I302_00244	I302_01128	A0A1B9GCK3	A0A1B9GF36	Uncharacterized protein.	Uncharacterized protein.	0.899
I302_00244	I302_02337	A0A1B9GCK3	A0A1B9G8X7	Uncharacterized protein.	Mannosyltransferase.	0.576
I302_00244	I302_02951	A0A1B9GCK3	A0A1B9GAS2	Uncharacterized protein.	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.	0.611
I302_00244	I302_03818	A0A1B9GCK3	A0A1B9G562	Uncharacterized protein.	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.	0.908
I302_00244	I302_04214	A0A1B9GCK3	A0A1B9G694	Uncharacterized protein.	Phosphatidylinositol glycan, class P.	0.926