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I303_03496 | Elongator complex protein 2. (780 aa) | ||||
I303_08446 | Uncharacterized protein. (293 aa) | ||||
I303_08670 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1326 aa) | ||||
I303_07570 | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase. (472 aa) | ||||
I303_07609 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (297 aa) | ||||
I303_06450 | Uncharacterized protein. (479 aa) | ||||
I303_05691 | Methyltransf_25 domain-containing protein. (294 aa) | ||||
I303_05775 | Uncharacterized protein. (381 aa) | ||||
NCS6 | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (361 aa) | ||||
I303_06317 | Methyltransf_11 domain-containing protein. (427 aa) | ||||
I303_05281 | Thiosulfate/3-mercaptopyruvate sulfurtransferase. (334 aa) | ||||
URM1 | Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...] (146 aa) | ||||
I303_04301 | Diphthamide biosynthesis protein 3. (155 aa) | ||||
I303_04714 | NADH dehydrogenase (Ubiquinone) 1 alpha subcomplex 4. (92 aa) | ||||
CFD1 | Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (353 aa) | ||||
I303_04098 | Uncharacterized protein. (322 aa) | ||||
I303_02902 | DPBB_1 domain-containing protein. (296 aa) | ||||
I303_03036 | Uncharacterized protein. (552 aa) | ||||
NCS2 | Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (531 aa) | ||||
I303_02085 | Adenylyltransferase and sulfurtransferase. (432 aa) | ||||
I303_02213 | Cysteine desulfurase IscS. (500 aa) | ||||
I303_00598 | Protein KTI12. (304 aa) | ||||
I303_00753 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (556 aa) | ||||
I303_00861 | Uncharacterized protein. (286 aa) |