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I303_08521 I303_08521 I303_08582 I303_08582 I303_08720 I303_08720 I303_08221 I303_08221 I303_08273 I303_08273 I303_07565 I303_07565 I303_07678 I303_07678 I303_07840 I303_07840 I303_07919 I303_07919 I303_08049 I303_08049 I303_08051 I303_08051 I303_08067 I303_08067 I303_07012 I303_07012 I303_07184 I303_07184 I303_07212 I303_07212 I303_07246 I303_07246 I303_07251 I303_07251 I303_07266 I303_07266 I303_07307 I303_07307 I303_07313 I303_07313 I303_07479 I303_07479 I303_07511 I303_07511 I303_06369 I303_06369 I303_06704 I303_06704 I303_06751 I303_06751 I303_06851 I303_06851 I303_05750 I303_05750 I303_05960 I303_05960 I303_06047 I303_06047 I303_06096 I303_06096 I303_06102 I303_06102 I303_06136 I303_06136 I303_06159 I303_06159 I303_05059 I303_05059 I303_05167 I303_05167 I303_05406 I303_05406 I303_05470 I303_05470 I303_05526 I303_05526 I303_05663 I303_05663 I303_04199 I303_04199 I303_04221 I303_04221 I303_04253 I303_04253 I303_04526 I303_04526 I303_04905 I303_04905 I303_03310 I303_03310 I303_03420 I303_03420 I303_03499 I303_03499 I303_03567 I303_03567 I303_03682 I303_03682 I303_03743 I303_03743 I303_03846 I303_03846 I303_03937 I303_03937 I303_04028 I303_04028 I303_04020 I303_04020 I303_02476 I303_02476 I303_02698 I303_02698 I303_03102 I303_03102 I303_03255 I303_03255 I303_01491 I303_01491 I303_01729 I303_01729 I303_01769 I303_01769 I303_01789 I303_01789 I303_01826 I303_01826 I303_01918 I303_01918 I303_01938 I303_01938 I303_02001 I303_02001 I303_02090 I303_02090 I303_02259 I303_02259 I303_02326 I303_02326 I303_02365 I303_02365 I303_02392 I303_02392 I303_00086 I303_00086 I303_00213 I303_00213 ADK1 ADK1 I303_00592 I303_00592 I303_00642 I303_00642 I303_00643 I303_00643 I303_00820 I303_00820 I303_00834 I303_00834 I303_00854 I303_00854 I303_00888 I303_00888 I303_00944 I303_00944 I303_00969 I303_00969 I303_00973 I303_00973 I303_01062 I303_01062 I303_01096 I303_01096 I303_01109 I303_01109 I303_01112 I303_01112 I303_01131 I303_01131 I303_01279 I303_01279 I303_01280 I303_01280
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I303_08521Uncharacterized protein. (794 aa)
I303_08582Glyceraldehyde-3-phosphate dehydrogenase. (339 aa)
I303_08720ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (540 aa)
I303_08221ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (547 aa)
I303_08273Acetyl-CoA carboxylase/biotin carboxylase. (2235 aa)
I303_07565Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (526 aa)
I303_076784HBT domain-containing protein. (180 aa)
I303_07840Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (292 aa)
I303_07919Pyruvate kinase; Belongs to the pyruvate kinase family. (583 aa)
I303_08049Acetyl-coenzyme A synthetase. (681 aa)
I303_08051Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (422 aa)
I303_08067Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (605 aa)
I303_07012Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (401 aa)
I303_07184Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (284 aa)
I303_07212V-type proton ATPase catalytic subunit A. (614 aa)
I303_07246Glutaryl-CoA dehydrogenase. (427 aa)
I303_07251Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (479 aa)
I303_07266Uncharacterized protein. (90 aa)
I303_07307Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (584 aa)
I303_07313Nucleoside diphosphate kinase. (152 aa)
I303_07479ATP synthase subunit gamma. (289 aa)
I303_07511Transferase. (218 aa)
I303_06369Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (286 aa)
I303_06704Phosphoribosylformylglycinamidine synthase. (1359 aa)
I303_06751Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
I303_06851Adenylate cyclase. (2364 aa)
I303_05750Triosephosphate isomerase. (238 aa)
I303_05960Phosphopantothenate-cysteine ligase. (378 aa)
I303_06047Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa)
I303_06096Acyl-CoA thioesterase II. (396 aa)
I303_06102Pyruvate dehydrogenase X component. (345 aa)
I303_06136Uncharacterized protein. (1490 aa)
I303_06159Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (330 aa)
I303_05059Phosphoribosylamine-glycine ligase. (815 aa)
I303_05167Probable acetate kinase. (432 aa)
I303_05406ATP synthase F1, delta subunit. (208 aa)
I303_05470HD domain-containing protein. (410 aa)
I303_05526Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (397 aa)
I303_05663Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (491 aa)
I303_04199Uncharacterized protein. (152 aa)
I303_04221Uncharacterized protein. (599 aa)
I303_04253Flavoprotein domain-containing protein. (353 aa)
I303_04526Long-chain acyl-CoA synthetase. (688 aa)
I303_04905ADSL_C domain-containing protein. (497 aa)
I303_033103-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (499 aa)
I303_03420GTP-binding protein 1. (628 aa)
I303_03499ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (173 aa)
I303_03567Glucose-6-phosphate isomerase; Belongs to the GPI family. (555 aa)
I303_03682Phosphotransferase. (484 aa)
I303_03743CTP_transf_like domain-containing protein. (373 aa)
I303_03846Nudix hydrolase domain-containing protein. (202 aa)
I303_039372-oxoglutarate dehydrogenase E2 component (Dihydrolipoamide succinyltransferase). (474 aa)
I303_04028F-type H+-transporting ATPase subunit delta. (169 aa)
I303_04020Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (362 aa)
I303_02476Phosphotransferase. (572 aa)
I303_02698Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. (957 aa)
I303_03102F-type H+-transporting ATPase subunit G. (166 aa)
I303_03255Enolase. (446 aa)
I303_01491Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (382 aa)
I303_01729Uncharacterized protein. (619 aa)
I303_01769Nudix hydrolase domain-containing protein. (318 aa)
I303_01789ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (873 aa)
I303_01826ATP-citrate synthase subunit 1. (1148 aa)
I303_01918Adenylate kinase; Belongs to the adenylate kinase family. (425 aa)
I303_01938Uncharacterized protein. (104 aa)
I303_02001Nucleoside-diphosphate kinase; Belongs to the NDK family. (222 aa)
I303_02090F-type H+-transporting ATPase subunit H. (125 aa)
I303_02259Adenine phosphoribosyltransferase. (180 aa)
I303_02326Adenosine kinase. (355 aa)
I303_023653-hydroxy-3-methylglutaryl coenzyme A reductase. (1292 aa)
I303_02392Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (413 aa)
I303_00086Uncharacterized protein. (76 aa)
I303_00213Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (554 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (332 aa)
I303_00592Nudix hydrolase domain-containing protein. (531 aa)
I303_006422,3-bisphosphoglycerate-independent phosphoglycerate mutase. (534 aa)
I303_00643Uncharacterized protein. (638 aa)
I303_00820GMP synthase [glutamine-hydrolyzing]. (551 aa)
I303_00834Guanylate kinase. (217 aa)
I303_00854F-type H+-transporting ATPase subunit B. (235 aa)
I303_00888F-type H+-transporting ATPase subunit J. (60 aa)
I303_00944Thioesterase. (522 aa)
I303_00969Dephospho-CoA kinase. (310 aa)
I303_00973Phosphoribosylglycinamide formyltransferase. (324 aa)
I303_01062Uncharacterized protein. (430 aa)
I303_01096AMP-binding domain-containing protein. (654 aa)
I303_01109Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (430 aa)
I303_01112Amidophosphoribosyltransferase. (556 aa)
I303_01131Pantothenate kinase. (556 aa)
I303_01279AMP deaminase. (861 aa)
I303_01280Uncharacterized protein. (257 aa)
Your Current Organism:
Kwoniella dejecticola
NCBI taxonomy Id: 1296121
Other names: Cryptococcus dejecticola CBS 10117, K. dejecticola CBS 10117, Kwoniella dejecticola CBS 10117
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