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I303_08521 | Uncharacterized protein. (794 aa) | ||||
I303_00820 | GMP synthase [glutamine-hydrolyzing]. (551 aa) | ||||
I303_00643 | Uncharacterized protein. (638 aa) | ||||
I303_00642 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase. (534 aa) | ||||
I303_00592 | Nudix hydrolase domain-containing protein. (531 aa) | ||||
I303_00545 | Epimerase domain-containing protein. (342 aa) | ||||
I303_00551 | 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase. (763 aa) | ||||
I303_00472 | Uncharacterized protein. (513 aa) | ||||
I303_00467 | FMN adenylyltransferase. (306 aa) | ||||
ADK1 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (332 aa) | ||||
I303_00393 | Ribonucleoside-diphosphate reductase small subunit. (398 aa) | ||||
I303_00381 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (727 aa) | ||||
I303_00213 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (554 aa) | ||||
I303_00086 | Uncharacterized protein. (76 aa) | ||||
I303_00034 | Uncharacterized protein. (757 aa) | ||||
I303_02392 | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (413 aa) | ||||
I303_02365 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (1292 aa) | ||||
I303_02326 | Adenosine kinase. (355 aa) | ||||
I303_02282 | HD domain-containing protein. (277 aa) | ||||
I303_02259 | Adenine phosphoribosyltransferase. (180 aa) | ||||
I303_02153 | Zn(2)-C6 fungal-type domain-containing protein. (841 aa) | ||||
I303_02090 | F-type H+-transporting ATPase subunit H. (125 aa) | ||||
I303_02001 | Nucleoside-diphosphate kinase; Belongs to the NDK family. (222 aa) | ||||
I303_01981 | NAD(P)H-hydrate epimerase. (242 aa) | ||||
I303_01966 | Allantoinase. (537 aa) | ||||
I303_01938 | Uncharacterized protein. (104 aa) | ||||
I303_01918 | Adenylate kinase; Belongs to the adenylate kinase family. (425 aa) | ||||
I303_01826 | ATP-citrate synthase subunit 1. (1148 aa) | ||||
I303_01789 | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (873 aa) | ||||
I303_01769 | Nudix hydrolase domain-containing protein. (318 aa) | ||||
I303_01739 | Thymidylate synthase. (350 aa) | ||||
I303_01729 | Uncharacterized protein. (619 aa) | ||||
I303_01719 | Mannose-6-phosphate isomerase, class I. (461 aa) | ||||
I303_01713 | Nudix hydrolase domain-containing protein. (388 aa) | ||||
I303_01708 | Nudix hydrolase domain-containing protein. (310 aa) | ||||
I303_01491 | Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (382 aa) | ||||
I303_03273 | Type I phosphodiesterase/nucleotide pyrophosphatase. (566 aa) | ||||
I303_03255 | Enolase. (446 aa) | ||||
I303_03256 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (636 aa) | ||||
I303_03233 | Hydrolase. (111 aa) | ||||
I303_03143 | Riboflavin kinase. (271 aa) | ||||
I303_03102 | F-type H+-transporting ATPase subunit G. (166 aa) | ||||
I303_02992 | Phosphoserine transaminase. (409 aa) | ||||
I303_02698 | Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. (957 aa) | ||||
I303_02672 | Bis(5'-adenosyl)-triphosphatase. (204 aa) | ||||
I303_02659 | Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (196 aa) | ||||
I303_02476 | Phosphotransferase. (572 aa) | ||||
I303_02459 | Uncharacterized protein. (638 aa) | ||||
I303_04020 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (362 aa) | ||||
I303_04028 | F-type H+-transporting ATPase subunit delta. (169 aa) | ||||
I303_03937 | 2-oxoglutarate dehydrogenase E2 component (Dihydrolipoamide succinyltransferase). (474 aa) | ||||
I303_03930 | dCMP deaminase. (377 aa) | ||||
I303_03876 | UDP-glucose:glycoprotein glucosyltransferase. (1623 aa) | ||||
I303_03846 | Nudix hydrolase domain-containing protein. (202 aa) | ||||
I303_03743 | CTP_transf_like domain-containing protein. (373 aa) | ||||
I303_03682 | Phosphotransferase. (484 aa) | ||||
I303_03567 | Glucose-6-phosphate isomerase; Belongs to the GPI family. (555 aa) | ||||
I303_03499 | ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (173 aa) | ||||
I303_03469 | Guanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. (731 aa) | ||||
I303_03420 | GTP-binding protein 1. (628 aa) | ||||
I303_03399 | GDP-mannose 4,6-dehydratase. (576 aa) | ||||
I303_03402 | Uncharacterized protein. (259 aa) | ||||
BNA1 | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (176 aa) | ||||
I303_03310 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (499 aa) | ||||
I303_04905 | ADSL_C domain-containing protein. (497 aa) | ||||
I303_04577 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (311 aa) | ||||
I303_04526 | Long-chain acyl-CoA synthetase. (688 aa) | ||||
I303_04410 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa) | ||||
I303_04272 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (350 aa) | ||||
I303_04253 | Flavoprotein domain-containing protein. (353 aa) | ||||
I303_04221 | Uncharacterized protein. (599 aa) | ||||
I303_04199 | Uncharacterized protein. (152 aa) | ||||
I303_05663 | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (491 aa) | ||||
I303_05526 | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (397 aa) | ||||
I303_05524 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (452 aa) | ||||
I303_05470 | HD domain-containing protein. (410 aa) | ||||
I303_05421 | Glutamine-fructose-6-phosphate transaminase (Isomerizing). (711 aa) | ||||
I303_05406 | ATP synthase F1, delta subunit. (208 aa) | ||||
I303_05172 | Vacuolar protein. (607 aa) | ||||
I303_05167 | Probable acetate kinase. (432 aa) | ||||
I303_05059 | Phosphoribosylamine-glycine ligase. (815 aa) | ||||
I303_05031 | Guanine deaminase. (476 aa) | ||||
I303_06191 | Uridine kinase; Belongs to the uridine kinase family. (592 aa) | ||||
I303_06159 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (330 aa) | ||||
I303_06136 | Uncharacterized protein. (1490 aa) | ||||
I303_06102 | Pyruvate dehydrogenase X component. (345 aa) | ||||
I303_06096 | Acyl-CoA thioesterase II. (396 aa) | ||||
I303_06047 | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa) | ||||
I303_06037 | NAD+ diphosphatase. (393 aa) | ||||
I303_06026 | Ribose-phosphate pyrophosphokinase. (327 aa) | ||||
I303_05991 | UDP-glucuronate decarboxylase. (457 aa) | ||||
I303_05960 | Phosphopantothenate-cysteine ligase. (378 aa) | ||||
I303_05945 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (861 aa) | ||||
I303_05767 | Carbamoyl-phosphate synthase, large subunit. (2277 aa) | ||||
I303_05750 | Triosephosphate isomerase. (238 aa) | ||||
I303_05776 | Hydrolase. (425 aa) | ||||
I303_06851 | Adenylate cyclase. (2364 aa) | ||||
I303_06829 | Orotate phosphoribosyltransferase. (223 aa) | ||||
I303_06759 | Nicotinamide riboside kinase. (258 aa) | ||||
I303_06751 | Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa) | ||||
I303_06704 | Phosphoribosylformylglycinamidine synthase. (1359 aa) | ||||
I303_06558 | NAD+ kinase. (1217 aa) | ||||
I303_06369 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (286 aa) | ||||
I303_07536 | Ribonucleoside-diphosphate reductase subunit M2. (435 aa) | ||||
I303_07511 | Transferase. (218 aa) | ||||
I303_07479 | ATP synthase subunit gamma. (289 aa) | ||||
I303_07424 | Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family. (562 aa) | ||||
I303_07408 | Uncharacterized protein. (310 aa) | ||||
I303_07313 | Nucleoside diphosphate kinase. (152 aa) | ||||
I303_07307 | Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (584 aa) | ||||
I303_07266 | Uncharacterized protein. (90 aa) | ||||
I303_07251 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (479 aa) | ||||
I303_07246 | Glutaryl-CoA dehydrogenase. (427 aa) | ||||
I303_07212 | V-type proton ATPase catalytic subunit A. (614 aa) | ||||
I303_07184 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (284 aa) | ||||
I303_07168 | N-acetyltransferase domain-containing protein. (234 aa) | ||||
I303_07090 | Uracil phosphoribosyltransferase. (230 aa) | ||||
I303_07075 | Uracil phosphoribosyltransferase. (221 aa) | ||||
I303_07012 | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (401 aa) | ||||
I303_07014 | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (281 aa) | ||||
I303_06998 | UDP-glucose 6-dehydrogenase. (468 aa) | ||||
I303_06976 | Uncharacterized protein. (203 aa) | ||||
I303_08067 | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (605 aa) | ||||
I303_08056 | UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (386 aa) | ||||
I303_08051 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (422 aa) | ||||
I303_08049 | Acetyl-coenzyme A synthetase. (681 aa) | ||||
I303_08007 | Dihydroorotase, homodimeric type. (359 aa) | ||||
I303_07989 | Isochorismatase domain-containing protein. (239 aa) | ||||
I303_07919 | Pyruvate kinase; Belongs to the pyruvate kinase family. (583 aa) | ||||
I303_07911 | Uncharacterized protein; Belongs to the alkaline phosphatase family. (664 aa) | ||||
I303_07857 | Mannose-1-phosphate guanyltransferase. (407 aa) | ||||
I303_07840 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (292 aa) | ||||
I303_07711 | DUF3421 domain-containing protein. (393 aa) | ||||
I303_07678 | 4HBT domain-containing protein. (180 aa) | ||||
I303_07567 | Mannose-6-phosphate isomerase. (436 aa) | ||||
I303_07565 | Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (526 aa) | ||||
I303_08348 | UDP-N-acetylglucosamine pyrophosphorylase. (549 aa) | ||||
I303_08273 | Acetyl-CoA carboxylase/biotin carboxylase. (2235 aa) | ||||
I303_08221 | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (547 aa) | ||||
I303_08219 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (928 aa) | ||||
I303_08193 | Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (308 aa) | ||||
I303_08181 | Nicotinate (Nicotinamide) nucleotide adenylyltransferase. (588 aa) | ||||
I303_08720 | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (540 aa) | ||||
I303_08636 | Uncharacterized protein. (1060 aa) | ||||
I303_08624 | Methylenetetrahydrofolate dehydrogenase (NAD+). (366 aa) | ||||
I303_08586 | Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (186 aa) | ||||
I303_08582 | Glyceraldehyde-3-phosphate dehydrogenase. (339 aa) | ||||
I303_01365 | Carbamoyl-phosphate synthase arginine-specific large chain. (1159 aa) | ||||
I303_01280 | Uncharacterized protein. (257 aa) | ||||
I303_01279 | AMP deaminase. (861 aa) | ||||
I303_01118 | Tryptophan 2,3-dioxygenase. (563 aa) | ||||
I303_01108 | NADH kinase. (396 aa) | ||||
I303_01152 | UTP--glucose-1-phosphate uridylyltransferase. (499 aa) | ||||
I303_01146 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (170 aa) | ||||
I303_01131 | Pantothenate kinase. (556 aa) | ||||
I303_01112 | Amidophosphoribosyltransferase. (556 aa) | ||||
I303_01109 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (430 aa) | ||||
I303_01096 | AMP-binding domain-containing protein. (654 aa) | ||||
I303_01092 | Thymidylate kinase. (220 aa) | ||||
I303_01062 | Uncharacterized protein. (430 aa) | ||||
I303_01022 | dUTP pyrophosphatase. (172 aa) | ||||
I303_00973 | Phosphoribosylglycinamide formyltransferase. (324 aa) | ||||
I303_00969 | Dephospho-CoA kinase. (310 aa) | ||||
I303_00935 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (301 aa) | ||||
BNA4 | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (526 aa) | ||||
I303_00972 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (639 aa) | ||||
I303_00905 | Ribose-phosphate pyrophosphokinase. (329 aa) | ||||
I303_00944 | Thioesterase. (522 aa) | ||||
BNA5 | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (465 aa) | ||||
I303_00914 | Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (267 aa) | ||||
I303_00888 | F-type H+-transporting ATPase subunit J. (60 aa) | ||||
I303_00854 | F-type H+-transporting ATPase subunit B. (235 aa) | ||||
I303_00834 | Guanylate kinase. (217 aa) |