(82 nodes) Glycerophospholipid metabolism network (Kwoniella dejecticola)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

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protein homology

Your Input:
	I303_05236	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. (1620 aa)
	I303_08490	acidPPc domain-containing protein. (406 aa)
	I303_08537	Glycerophosphodiesterase. (377 aa)
	I303_08574	Phospholipase. (856 aa)
	I303_08696	Uncharacterized protein. (378 aa)
	I303_08126	PI-PLC Y-box domain-containing protein. (313 aa)
	I303_08247	Abhydrolase_2 domain-containing protein. (230 aa)
	I303_08246	Acyl-protein thioesterase 1. (238 aa)
	I303_07770	PAP2 domain-containing protein. (350 aa)
	I303_07827	acidPPc domain-containing protein. (385 aa)
	I303_07863	Transmembrane protein. (1566 aa)
	I303_07924	LNS2 domain-containing protein. (1037 aa)
	I303_07951	PLA2c domain-containing protein. (161 aa)
	I303_07948	Lysophospholipase. (658 aa)
	I303_08061	Phosphatidylserine decarboxylase. (441 aa)
	I303_08097	Uncharacterized protein. (443 aa)
	I303_06983	Uncharacterized protein. (504 aa)
	I303_07146	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (548 aa)
	I303_07288	Betaine lipid synthase. (864 aa)
	I303_07337	Patatin-like phospholipase domain-containing protein. (964 aa)
	I303_07366	Phospholipase. (858 aa)
	I303_07454	Cardiolipin-specific phospholipase. (586 aa)
	I303_07492	Fructosamine kinase; Belongs to the fructosamine kinase family. (318 aa)
	I303_06504	Glycerophosphoryl diester phosphodiesterase. (431 aa)
	I303_06505	PlsC domain-containing protein. (590 aa)
	I303_06594	Uncharacterized protein. (1080 aa)
	I303_06655	Ubiquitin thioesterase. (301 aa)
	I303_06717	C2 domain-containing protein. (1416 aa)
	I303_06760	Choline kinase. (520 aa)
	I303_06880	Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family. (1242 aa)
	I303_06947	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (580 aa)
	I303_05680	Uncharacterized protein. (167 aa)
	I303_05866	HAD hydrolase. (372 aa)
	PSD1	Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (519 aa)
	I303_06113	Abhydrolase_2 domain-containing protein. (307 aa)
	I303_05216	JmjC domain-containing protein. (359 aa)
	I303_05319	APH domain-containing protein. (344 aa)
	I303_05617	Phospholipase D. (1820 aa)
	I303_05658	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC). (329 aa)
	I303_04139	Uncharacterized protein. (353 aa)
	I303_04140	Uncharacterized protein. (355 aa)
	I303_04156	Uncharacterized protein. (326 aa)
	I303_04159	Uncharacterized protein. (724 aa)
	I303_04187	Uncharacterized protein. (390 aa)
	I303_04364	Lysophospholipid acyltransferase; Belongs to the membrane-bound acyltransferase family. (594 aa)
	I303_04740	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (344 aa)
	I303_03690	Uncharacterized protein. (410 aa)
	I303_03693	Acyltransferase. (429 aa)
	I303_03719	Tafazzin family protein; Belongs to the taffazin family. (347 aa)
	I303_04095	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (359 aa)
	I303_04126	Sterol esterase. (600 aa)
	I303_02746	Lipase_3 domain-containing protein. (417 aa)
	I303_02970	CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (245 aa)
	I303_02985	COesterase domain-containing protein. (743 aa)
	I303_01591	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (284 aa)
	I303_01604	Membrane protein. (577 aa)
	I303_01609	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (655 aa)
	I303_01632	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (615 aa)
	I303_01633	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (694 aa)
	PSD2	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (1300 aa)
	I303_01795	EXS domain-containing protein. (590 aa)
	I303_01887	Phosphatidate cytidylyltransferase; Belongs to the CDS family. (650 aa)
	I303_02010	GP-PDE domain-containing protein. (373 aa)
	I303_02110	MATH domain-containing protein. (677 aa)
	I303_02184	Endoplasmic reticulum protein. (581 aa)
	I303_02250	Phosphatidylserine decarboxylase. (404 aa)
	I303_02363	Ethanolaminephosphotransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (430 aa)
	I303_00087	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (529 aa)
	I303_00092	C2 domain-containing protein. (1283 aa)
	I303_00143	Lipase_GDSL domain-containing protein. (427 aa)
	I303_00263	Choline-phosphate cytidylyltransferase. (476 aa)
	I303_00470	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (364 aa)
	I303_00701	Uncharacterized protein. (781 aa)
	I303_00897	CDP-diacylglycerol-inositol 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (310 aa)
	I303_00981	GP-PDE domain-containing protein. (389 aa)
	I303_00965	Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (796 aa)
	I303_01075	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. (631 aa)
	I303_01138	Uncharacterized protein. (469 aa)
	I303_01198	Glycerol-3-phosphate O-acyltransferase/dihydroxyacetone phosphate acyltransferase. (774 aa)
	I303_01252	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (394 aa)
	I303_01376	Cardiolipin synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (317 aa)
	I303_01433	Uncharacterized protein. (148 aa)

Your Current Organism:

Kwoniella dejecticola

NCBI taxonomy Id: 1296121
Other names: Cryptococcus dejecticola CBS 10117, K. dejecticola CBS 10117, Kwoniella dejecticola CBS 10117

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I303_00087	I303_02363	A0A1A6ADX8	A0A1A6ADN2	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	Ethanolaminephosphotransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.563
I303_00087	I303_07924	A0A1A6ADX8	A0A1A5ZW25	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	LNS2 domain-containing protein.	0.716
I303_00092	I303_02363	A0A1A6ADY4	A0A1A6ADN2	C2 domain-containing protein.	Ethanolaminephosphotransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.559
I303_00092	I303_04187	A0A1A6ADY4	A0A1A6A486	C2 domain-containing protein.	Uncharacterized protein.	0.556
I303_00092	I303_05236	A0A1A6ADY4	A0A1A6A2U9	C2 domain-containing protein.	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	0.557
I303_00092	I303_05617	A0A1A6ADY4	A0A1A6A3X3	C2 domain-containing protein.	Phospholipase D.	0.465
I303_00092	I303_07366	A0A1A6ADY4	A0A1A5ZXR7	C2 domain-containing protein.	Phospholipase.	0.465
I303_00092	PSD1	A0A1A6ADY4	A0A1A6A0Z4	C2 domain-containing protein.	Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.	0.561
I303_00143	I303_00470	A0A1A6AE31	A0A1A6AF49	Lipase_GDSL domain-containing protein.	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.529
I303_00143	I303_02110	A0A1A6AE31	A0A1A6ACW3	Lipase_GDSL domain-containing protein.	MATH domain-containing protein.	0.521
I303_00143	I303_02363	A0A1A6AE31	A0A1A6ADN2	Lipase_GDSL domain-containing protein.	Ethanolaminephosphotransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.782
I303_00143	I303_03693	A0A1A6AE31	A0A1A6A7E8	Lipase_GDSL domain-containing protein.	Acyltransferase.	0.549
I303_00143	I303_04187	A0A1A6AE31	A0A1A6A486	Lipase_GDSL domain-containing protein.	Uncharacterized protein.	0.786
I303_00143	I303_05216	A0A1A6AE31	A0A1A6A2S6	Lipase_GDSL domain-containing protein.	JmjC domain-containing protein.	0.636
I303_00143	I303_05236	A0A1A6AE31	A0A1A6A2U9	Lipase_GDSL domain-containing protein.	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.	0.787
I303_00143	I303_05658	A0A1A6AE31	A0A1A6A417	Lipase_GDSL domain-containing protein.	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).	0.781
I303_00143	I303_05680	A0A1A6AE31	A0A1A6A021	Lipase_GDSL domain-containing protein.	Uncharacterized protein.	0.783
I303_00143	I303_06113	A0A1A6AE31	A0A1A6A1A0	Lipase_GDSL domain-containing protein.	Abhydrolase_2 domain-containing protein.	0.521
I303_00143	I303_06504	A0A1A6AE31	A0A1A5ZYQ8	Lipase_GDSL domain-containing protein.	Glycerophosphoryl diester phosphodiesterase.	0.518
I303_00143	I303_07951	A0A1A6AE31	A0A1A5ZW57	Lipase_GDSL domain-containing protein.	PLA2c domain-containing protein.	0.636