(38 nodes) Two-component regulatory system, and His Kinase A (phosphoacceptor) domain network (Intestinimonas butyriciproducens)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	ALP92741.1	Sensor histidine kinase VanS. (380 aa)
	ALP92776.1	Osmolarity sensory histidine kinase EnvZ. (357 aa)
	ALP92803.1	Two-component response regulator. (230 aa)
	ALP92804.1	Phosphate regulon sensor protein PhoR (SphS). (470 aa)
	ALP92839.1	D-binding response regulator KdpE. (243 aa)
	ALP92840.1	Osmosensitive K+ channel histidine kinase KdpD. (356 aa)
	ALP93052.1	Integral membrane protein. (385 aa)
	ALP93053.1	Hypothetical protein. (549 aa)
	ALP93054.1	Phosphate regulon transcriptional regulatory protein PhoB (SphR). (222 aa)
	ALP93282.1	Phosphate regulon transcriptional regulatory protein PhoB (SphR). (231 aa)
	ALP93283.1	Hypothetical protein. (699 aa)
	ALP93542.1	Sensor histidine kinase. (435 aa)
	ALP93543.1	Regulation of D-alanyl-lipoteichoic acid biosynthesis, DltRNA. (226 aa)
	ALP93710.1	Regulation of D-alanyl-lipoteichoic acid biosynthesis, DltRNA. (222 aa)
	ALP93711.1	Sensor histidine kinase. (402 aa)
	ALP93839.1	Regulation of D-alanyl-lipoteichoic acid biosynthesis, DltRNA. (250 aa)
	ALP93840.1	Sensor histidine kinase. (410 aa)
	ALP94242.1	Sensor histidine kinase. (449 aa)
	ALP94243.1	Phosphate regulon transcriptional regulatory protein PhoB (SphR). (239 aa)
	ALP94540.1	Two-component response regulator yycF. (231 aa)
	ALP94541.1	Phosphate regulon sensor protein PhoR (SphS). (469 aa)
	ALP94662.1	Phosphate regulon sensor protein PhoR (SphS). (469 aa)
	ALP94663.1	Two-component response regulator. (229 aa)
	ALP94664.1	Lipoprotein, putative. (463 aa)
	ALP94845.1	Phleomycin binding protein, ankyrin likeue, bleomycin and transport protein. (363 aa)
	ALP94847.1	Hypothetical protein. (38 aa)
	ALP94848.1	D-binding response regulator, OmpR family. (170 aa)
	ALP94849.1	Sensor histidine kinase. (223 aa)
	ALP94850.1	Two-component hybrid sensor and regulator. (241 aa)
	ALP94851.1	Hypothetical protein. (68 aa)
	ALP94899.1	Two-component response regulator. (233 aa)
	ALP94900.1	Hypothetical protein. (691 aa)
	ALP94982.1	Spore germination protein. (310 aa)
	ALP94983.1	Phosphate regulon sensor protein PhoR (SphS). (489 aa)
	ALP94984.1	Two-component response regulator. (228 aa)
	ALP95036.1	Phosphate regulon sensor protein PhoR (SphS). (425 aa)
	ALP95037.1	Phosphate regulon transcriptional regulatory protein PhoB (SphR). (222 aa)
	ALP95489.1	Vancomycin response regulator VanR. (263 aa)

Your Current Organism:

Intestinimonas butyriciproducens

NCBI taxonomy Id: 1297617
Other names: CCUG 63529, Candidatus Clostridium anorexicus, DSM 26588, I. butyriciproducens, Intestinimonas butyriciproducens Klaring et al. 2013, Pseudoflavonifractor sp. 2-1.1, Pseudoflavonifractor sp. SRB-521-5-I, strain SRB-521-5-I

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALP92741.1	ALP92803.1	IB211_00346	IB211_00408	Sensor histidine kinase VanS.	Two-component response regulator.	0.798
ALP92741.1	ALP92839.1	IB211_00346	IB211_00444c	Sensor histidine kinase VanS.	D-binding response regulator KdpE.	0.729
ALP92741.1	ALP92840.1	IB211_00346	IB211_00445c	Sensor histidine kinase VanS.	Osmosensitive K+ channel histidine kinase KdpD.	0.405
ALP92741.1	ALP93054.1	IB211_00346	IB211_00659c	Sensor histidine kinase VanS.	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	0.818
ALP92741.1	ALP93282.1	IB211_00346	IB211_00888	Sensor histidine kinase VanS.	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	0.835
ALP92741.1	ALP93543.1	IB211_00346	IB211_01150c	Sensor histidine kinase VanS.	Regulation of D-alanyl-lipoteichoic acid biosynthesis, DltRNA.	0.702
ALP92741.1	ALP93710.1	IB211_00346	IB211_01317	Sensor histidine kinase VanS.	Regulation of D-alanyl-lipoteichoic acid biosynthesis, DltRNA.	0.726
ALP92741.1	ALP93839.1	IB211_00346	IB211_01446	Sensor histidine kinase VanS.	Regulation of D-alanyl-lipoteichoic acid biosynthesis, DltRNA.	0.685
ALP92741.1	ALP94243.1	IB211_00346	IB211_01852c	Sensor histidine kinase VanS.	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	0.837
ALP92741.1	ALP94540.1	IB211_00346	IB211_02149c	Sensor histidine kinase VanS.	Two-component response regulator yycF.	0.805
ALP92741.1	ALP94663.1	IB211_00346	IB211_02272c	Sensor histidine kinase VanS.	Two-component response regulator.	0.754
ALP92741.1	ALP94848.1	IB211_00346	IB211_02457	Sensor histidine kinase VanS.	D-binding response regulator, OmpR family.	0.493
ALP92741.1	ALP94850.1	IB211_00346	IB211_02459	Sensor histidine kinase VanS.	Two-component hybrid sensor and regulator.	0.682
ALP92741.1	ALP94899.1	IB211_00346	IB211_02508	Sensor histidine kinase VanS.	Two-component response regulator.	0.842
ALP92741.1	ALP94984.1	IB211_00346	IB211_02593c	Sensor histidine kinase VanS.	Two-component response regulator.	0.828
ALP92741.1	ALP95037.1	IB211_00346	IB211_02646c	Sensor histidine kinase VanS.	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	0.793
ALP92741.1	ALP95489.1	IB211_00346	IB211_03098c	Sensor histidine kinase VanS.	Vancomycin response regulator VanR.	0.986
ALP92776.1	ALP92803.1	IB211_00381	IB211_00408	Osmolarity sensory histidine kinase EnvZ.	Two-component response regulator.	0.616
ALP92776.1	ALP92839.1	IB211_00381	IB211_00444c	Osmolarity sensory histidine kinase EnvZ.	D-binding response regulator KdpE.	0.604
ALP92776.1	ALP93054.1	IB211_00381	IB211_00659c	Osmolarity sensory histidine kinase EnvZ.	Phosphate regulon transcriptional regulatory protein PhoB (SphR).	0.655

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