STRINGSTRING
ALP92540.1 ALP92540.1 ALP95732.1 ALP95732.1 prs prs ALP95710.1 ALP95710.1 ALP95681.1 ALP95681.1 ALP95657.1 ALP95657.1 ALP95636.1 ALP95636.1 ALP95610.1 ALP95610.1 ALP95609.1 ALP95609.1 ALP95594.1 ALP95594.1 ALP95552.1 ALP95552.1 ALP95542.1 ALP95542.1 ALP95514.1 ALP95514.1 ALP95512.1 ALP95512.1 ALP95501.1 ALP95501.1 aroK-2 aroK-2 adk adk ALP95294.1 ALP95294.1 tdk tdk ALP95251.1 ALP95251.1 ALP95140.1 ALP95140.1 ALP95099.1 ALP95099.1 proB proB pgk pgk tpiA tpiA gpmI gpmI eno eno udk udk ALP95051.1 ALP95051.1 ALP95036.1 ALP95036.1 ALP95022.1 ALP95022.1 ALP94983.1 ALP94983.1 ALP94934.1 ALP94934.1 ALP94901.1 ALP94901.1 ALP94900.1 ALP94900.1 ALP94890.1 ALP94890.1 ALP94852.1 ALP94852.1 ALP94850.1 ALP94850.1 ALP94849.1 ALP94849.1 ALP94810.1 ALP94810.1 rbsK-2 rbsK-2 ALP94784.1 ALP94784.1 glpK glpK ALP94754.1 ALP94754.1 ALP94748.1 ALP94748.1 ALP94739.1 ALP94739.1 ALP94690.1 ALP94690.1 ALP94687.1 ALP94687.1 ALP94684.1 ALP94684.1 ALP94678.1 ALP94678.1 ALP94672.1 ALP94672.1 ALP94662.1 ALP94662.1 ppk ppk ALP94541.1 ALP94541.1 argB-2 argB-2 coaX-3 coaX-3 ALP94405.1 ALP94405.1 ALP94404.1 ALP94404.1 anmK anmK ALP94242.1 ALP94242.1 ALP94227.1 ALP94227.1 ALP94213.1 ALP94213.1 pfkA pfkA pfp pfp coaE coaE selD selD hprK hprK nadK nadK coaX-2 coaX-2 ALP94021.1 ALP94021.1 gmk gmk cmk cmk pyrH pyrH ALP93906.1 ALP93906.1 ALP93904.1 ALP93904.1 ALP93856.1 ALP93856.1 ALP93840.1 ALP93840.1 ALP93796.1 ALP93796.1 ALP93783.1 ALP93783.1 ALP93735.1 ALP93735.1 ALP93711.1 ALP93711.1 ALP93702.1 ALP93702.1 coaX coaX ALP93674.1 ALP93674.1 ALP93624.1 ALP93624.1 ALP93605.1 ALP93605.1 ALP93591.1 ALP93591.1 spoIIAB spoIIAB ALP93542.1 ALP93542.1 ALP93495.1 ALP93495.1 ALP93458.1 ALP93458.1 ackA ackA ALP93343.1 ALP93343.1 ispE ispE ALP93283.1 ALP93283.1 tmk tmk ALP93245.1 ALP93245.1 ALP93236.1 ALP93236.1 ALP93195.1 ALP93195.1 ALP93173.1 ALP93173.1 ALP93160.1 ALP93160.1 ALP93159.1 ALP93159.1 ALP93088.1 ALP93088.1 ALP93053.1 ALP93053.1 ALP93028.1 ALP93028.1 ALP93015.1 ALP93015.1 ALP92976.1 ALP92976.1 ALP92949.1 ALP92949.1 pgi pgi rbsK rbsK ALP92840.1 ALP92840.1 ALP92804.1 ALP92804.1 ALP92787.1 ALP92787.1 ALP92781.1 ALP92781.1 ALP92776.1 ALP92776.1 ALP92741.1 ALP92741.1 ALP92709.1 ALP92709.1 ALP92555.1 ALP92555.1 aroK aroK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALP92540.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (740 aa)
ALP95732.1Carbamate kinase; Belongs to the carbamate kinase family. (310 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (319 aa)
ALP95710.12-dehydro-3-deoxygluconate kinase. (356 aa)
ALP95681.12-dehydro-3-deoxygluconate kinase. (117 aa)
ALP95657.1ROK family protein (putative glucokinase). (270 aa)
ALP95636.1Pyruvate,phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (875 aa)
ALP95610.1Hypothetical protein. (122 aa)
ALP95609.1Sensory box histidine kinase/response regulator. (819 aa)
ALP95594.1Transcription regulator; Contains diacylglycerol kinase catalytic domain. (297 aa)
ALP95552.1Xylulose kinase. (510 aa)
ALP95542.1ROK family protein. (307 aa)
ALP95514.1Hypothetical protein. (86 aa)
ALP95512.1Hypothetical protein. (282 aa)
ALP95501.1Hypothetical protein. (414 aa)
aroK-2Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (213 aa)
ALP95294.1Phosphate regulon sensor protein PhoR (SphS). (593 aa)
tdkThymidine kinase. (193 aa)
ALP95251.1Carbamate kinase; Belongs to the carbamate kinase family. (313 aa)
ALP95140.1Sensor histidine kinase. (482 aa)
ALP95099.1Transcription regulator; Contains diacylglycerol kinase catalytic domain. (307 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (274 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (396 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (307 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (506 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa)
udkUridine kinase. (208 aa)
ALP95051.1Pseudouridine kinase. (360 aa)
ALP95036.1Phosphate regulon sensor protein PhoR (SphS). (425 aa)
ALP95022.1Ethanolamine utilization protein EutQ. (147 aa)
ALP94983.1Phosphate regulon sensor protein PhoR (SphS). (489 aa)
ALP94934.1Sensory box histidine kinase/response regulator. (861 aa)
ALP94901.1GGDEF domain. (308 aa)
ALP94900.1Hypothetical protein. (691 aa)
ALP94890.1Pyridoxal kinase; Belongs to the pyridoxine kinase family. (279 aa)
ALP94852.1Sensory box histidine kinase/response regulator. (848 aa)
ALP94850.1Two-component hybrid sensor and regulator. (241 aa)
ALP94849.1Sensor histidine kinase. (223 aa)
ALP94810.1Fructokinase. (317 aa)
rbsK-2Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (337 aa)
ALP94784.1N-acetylhexosamine 1-kinase. (369 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (501 aa)
ALP94754.1Ethanolamine sensory transduction histidine kinase. (474 aa)
ALP94748.1Hypothetical protein. (456 aa)
ALP94739.1Hypothetical protein. (487 aa)
ALP94690.1Hypothetical protein. (429 aa)
ALP94687.1Galactokinase; Belongs to the GHMP kinase family. (427 aa)
ALP94684.1Two-component sensor kinase yesM. (599 aa)
ALP94678.1Hexokinase. (434 aa)
ALP94672.1Thiamin pyrophosphokinase. (206 aa)
ALP94662.1Phosphate regulon sensor protein PhoR (SphS). (469 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (715 aa)
ALP94541.1Phosphate regulon sensor protein PhoR (SphS). (469 aa)
argB-2Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (284 aa)
coaX-3Pantothenate kinase type III, CoaX-like; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (261 aa)
ALP94405.15-methylthioribose kinase. (410 aa)
ALP94404.1Methyl-accepting chemotaxis protein. (407 aa)
anmKAnhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (405 aa)
ALP94242.1Sensor histidine kinase. (449 aa)
ALP94227.1Hypothetical protein. (383 aa)
ALP94213.1Hypothetical protein. (145 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (328 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (414 aa)
coaEHypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (201 aa)
selDSelenide,water dikinase; Synthesizes selenophosphate from selenide and ATP. (346 aa)
hprKHPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...] (317 aa)
nadKDNA kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (241 aa)
coaX-2Pantothenate kinase type III, CoaX-like; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (221 aa)
ALP94021.1Serine/threonine protein kinase PrkC, regulator of stationary phase. (693 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (203 aa)
cmkCytidylate kinase. (225 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa)
ALP93906.1Hypothetical protein. (126 aa)
ALP93904.1Adenosylcobinamide-phosphate guanylyltransferase. (171 aa)
ALP93856.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter). (656 aa)
ALP93840.1Sensor histidine kinase. (410 aa)
ALP93796.1Hypothetical protein. (154 aa)
ALP93783.1Glutamate-rich protein grpB. (176 aa)
ALP93735.1Sensor histidine kinase. (301 aa)
ALP93711.1Sensor histidine kinase. (402 aa)
ALP93702.1Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF). (372 aa)
coaXPantothenate kinase type III, CoaX-like; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (261 aa)
ALP93674.1Hypothetical protein. (42 aa)
ALP93624.1Sensor histidine kinase. (406 aa)
ALP93605.1Hypothetical protein. (500 aa)
ALP93591.1Aspartokinase; Belongs to the aspartokinase family. (407 aa)
spoIIABAnti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (148 aa)
ALP93542.1Sensor histidine kinase. (435 aa)
ALP93495.1Hypothetical protein. (475 aa)
ALP93458.1Hypothetical protein. (499 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (455 aa)
ALP93343.1Fructoselysine kinase. (265 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (286 aa)
ALP93283.1Hypothetical protein. (699 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (222 aa)
ALP93245.1UDP-galactose-lipid carrier transferase. (491 aa)
ALP93236.1Pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa)
ALP93195.1Sensor histidine kinase. (421 aa)
ALP93173.1Two-component sensor histidine kinase. (446 aa)
ALP93160.12-dehydro-3-deoxygluconate kinase. (341 aa)
ALP93159.12-dehydro-3-deoxygluconate kinase. (363 aa)
ALP93088.1Cytidylate kinase. (197 aa)
ALP93053.1Hypothetical protein. (549 aa)
ALP93028.1Uridine kinase. (357 aa)
ALP93015.1Periplasmic protein kinase ArgK; GTPases of G3E family. (374 aa)
ALP92976.1Riboflavin kinase; Belongs to the ribF family. (311 aa)
ALP92949.1Sensory box/GGDEF family protein. (271 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (441 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (332 aa)
ALP92840.1Osmosensitive K+ channel histidine kinase KdpD. (356 aa)
ALP92804.1Phosphate regulon sensor protein PhoR (SphS). (470 aa)
ALP92787.1Sensory transduction histidine kinase. (196 aa)
ALP92781.1Anti-sigma B factor RsbT. (142 aa)
ALP92776.1Osmolarity sensory histidine kinase EnvZ. (357 aa)
ALP92741.1Sensor histidine kinase VanS. (380 aa)
ALP92709.12-dehydro-3-deoxygluconate kinase. (341 aa)
ALP92555.1Uridine kinase. (314 aa)
aroKShikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (164 aa)
Your Current Organism:
Intestinimonas butyriciproducens
NCBI taxonomy Id: 1297617
Other names: CCUG 63529, Candidatus Clostridium anorexicus, DSM 26588, I. butyriciproducens, Intestinimonas butyriciproducens Klaring et al. 2013, Pseudoflavonifractor sp. 2-1.1, Pseudoflavonifractor sp. SRB-521-5-I, strain SRB-521-5-I
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