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| | ALP94912.1 | Diaminopimelate decarboxylase. (429 aa) |
| | ALP94994.1 | Arogenate dehydrogenase. (280 aa) |
| | ALP95759.1 | Seryl-tRNA synthetase. (435 aa) |
| | ALP95735.1 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (412 aa) |
| | ALP95734.1 | Cysteine synthase. (491 aa) |
| | ALP95711.1 | Dihydrodipicolinate synthase; Belongs to the DapA family. (295 aa) |
| | ALP95698.1 | Glutamate synthase small chain. (465 aa) |
| | ALP95684.1 | Hypothetical protein. (240 aa) |
| | ALP95659.1 | N-acetylneuraminate lyase. (301 aa) |
| | ALP95600.1 | Branched-chain amino acid aminotransferase. (354 aa) |
| | ALP95556.1 | Allantoin racemase. (217 aa) |
| | ALP95525.1 | Hypothetical protein. (172 aa) |
| | aroE | Shikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (283 aa) |
| | aroQ | 3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (143 aa) |
| | aroK-2 | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (325 aa) |
| | aroA | 5-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (388 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (359 aa) |
| | ALP95396.1 | Lipoate-protein ligase A. (330 aa) |
| | ALP95331.1 | Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (268 aa) |
| | ALP95256.1 | Hypothetical protein. (224 aa) |
| | ALP95253.1 | Acetylornithine deacetylase. (470 aa) |
| | ALP95144.1 | Phosphoserine phosphatase. (491 aa) |
| | ALP95143.1 | 5-methyltetrahydrofolate--homocysteine methyltransferase. (415 aa) |
| | ALP95118.1 | Oxidoreductase of aldo/keto reductase family, subgroup 1. (281 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (416 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (274 aa) |
| | ALP95066.1 | Glutamine-hydrolyzing asparagine synthetase. (616 aa) |
| | ALP95056.1 | Putative poly(beta-D-mannuronate) O-acetylase; Belongs to the membrane-bound acyltransferase family. (467 aa) |
| | ALP92440.1 | Metal dependent hydrolase. (280 aa) |
| | aroK | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (164 aa) |
| | ALP92559.1 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (355 aa) |
| | ALP92564.1 | Hypothetical protein. (205 aa) |
| | ALP92589.1 | Radical SAM domain protein. (205 aa) |
| | ALP92596.1 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (294 aa) |
| | ALP92597.1 | Methionine synthase activation domain. (216 aa) |
| | ALP92598.1 | 5-methyltetrahydrofolate--homocysteine methyltransferase. (794 aa) |
| | ALP92678.1 | Homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. (374 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (431 aa) |
| | ALP92778.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (389 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (361 aa) |
| | ALP92845.1 | Hypothetical protein. (225 aa) |
| | ALP92851.1 | Dihydrodipicolinate synthase; Belongs to the DapA family. (291 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (307 aa) |
| | ALP92916.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (317 aa) |
| | ALP92943.1 | Hydroxymethylglutaryl-CoA lyase. (302 aa) |
| | ALP92960.1 | Dihydrofolate reductase. (158 aa) |
| | ALP92993.1 | Acetyl-coenzyme A carboxyl transferase alpha chain. (513 aa) |
| | metAA | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (304 aa) |
| | ALP93058.1 | Threonine dehydratase. (404 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (553 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (372 aa) |
| | ALP93075.1 | Acetolactate synthase small subunit. (186 aa) |
| | ALP93076.1 | Acetolactate synthase large subunit. (569 aa) |
| | ALP93162.1 | Glutamate synthase small chain. (101 aa) |
| | ALP93163.1 | Glutamate synthase small chain. (328 aa) |
| | ALP93208.1 | Cysteine synthase. (307 aa) |
| | ALP93221.1 | Putative poly(beta-D-mannuronate) O-acetylase; Belongs to the membrane-bound acyltransferase family. (473 aa) |
| | ALP93269.1 | C_GCAxxG_C_C family protein. (130 aa) |
| | asnA | Aspartate--ammonia ligase. (337 aa) |
| | ALP93332.1 | Homoserine kinase. (200 aa) |
| | ALP93362.1 | Putative poly(beta-D-mannuronate) O-acetylase; Belongs to the membrane-bound acyltransferase family. (484 aa) |
| | ilvD-2 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (557 aa) |
| | ALP93590.1 | Homoserine dehydrogenase. (403 aa) |
| | ALP93591.1 | Aspartokinase; Belongs to the aspartokinase family. (407 aa) |
| | ALP93664.1 | Substrate-specific component of predicted ECF transporter. (200 aa) |
| | ALP93671.1 | Substrate-specific component of predicted ECF transporter. (200 aa) |
| | ALP93766.1 | Nitrogenase FeMo-cofactor synthesis FeS core scaffold and assembly protein NifB. (289 aa) |
| | ALP93796.1 | Hypothetical protein. (154 aa) |
| | ALP93804.1 | Oxidoreductase, aldo/keto reductase family. (279 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (278 aa) |
| | dapL | L,L-diaminopimelate aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (404 aa) |
| | ALP93819.1 | Glutamate synthase large chain. (1533 aa) |
| | ALP93820.1 | Glutamate synthase small chain. (486 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (DP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (280 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (355 aa) |
| | ALP93909.1 | L-threonine 3-O-phosphate decarboxylase. (352 aa) |
| | hisZ | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (389 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (213 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (424 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (192 aa) |
| | hisH | Imidazole glycerol phosphate synthase amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (204 aa) |
| | hisA | Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (241 aa) |
| | hisF | Imidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa) |
| | ALP93950.1 | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. (109 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (425 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (161 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (358 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (266 aa) |
| | ALP94070.1 | Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (361 aa) |
| | dapA-2 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (304 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (258 aa) |
| | argR | Arginine pathway regulatory protein ArgR, repressor of arg regulon; Regulates arginine biosynthesis genes. (150 aa) |
| | selD | Selenide,water dikinase; Synthesizes selenophosphate from selenide and ATP. (346 aa) |
| | ALP94153.1 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (688 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (336 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (264 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (203 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (395 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (260 aa) |
| | mtnA | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (341 aa) |
| | ALP94177.1 | Hypothetical protein. (135 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1089 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (361 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (561 aa) |
| | ALP94272.1 | Glutamate synthase large chain. (51 aa) |
| | ALP94357.1 | Hypothetical protein. (66 aa) |
| | ALP94373.1 | Acyl-ACP thioesterase. (246 aa) |
| | ALP94405.1 | 5-methylthioribose kinase. (410 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa) |
| | ALP94450.1 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (375 aa) |
| | ALP94457.1 | Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (393 aa) |
| | argB-2 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (284 aa) |
| | argJ | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (420 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (308 aa) |
| | argH | Argininosuccinate lyase. (460 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (408 aa) |
| | ALP94500.1 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. (239 aa) |
| | ALP94546.1 | Acetylornithine deacetylase. (379 aa) |
| | ALP94571.1 | Serine acetyltransferase. (217 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa) |
| | plsX | Phosphate:acyl-ACP acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (345 aa) |
| | fabZ | (3R)-hydroxymyristoyl dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (141 aa) |
| | ALP94711.1 | 3-oxoacyl synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (413 aa) |
| | ALP94713.1 | Malonyl CoA-acyl carrier protein transacylase. (309 aa) |
| | fabH | 3-oxoacyl synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (313 aa) |
| | accA | Acetyl-coenzyme A carboxyl transferase alpha chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (270 aa) |
| | accD | Acetyl-coenzyme A carboxyl transferase beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (294 aa) |
| | ALP94718.1 | Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (457 aa) |
| | ALP94719.1 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (144 aa) |
| | acpP-2 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (75 aa) |
| | ALP94732.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (338 aa) |
| | ALP94784.1 | N-acetylhexosamine 1-kinase. (369 aa) |
