STRINGSTRING
recF recF ALP92415.1 ALP92415.1 lexA lexA ALP92435.1 ALP92435.1 ALP92471.1 ALP92471.1 ALP92496.1 ALP92496.1 ALP92497.1 ALP92497.1 ligA ligA recD2 recD2 ALP92530.1 ALP92530.1 ALP92532.1 ALP92532.1 ALP92539.1 ALP92539.1 mutS mutS mutL mutL ALP92636.1 ALP92636.1 ALP92663.1 ALP92663.1 ALP92679.1 ALP92679.1 ALP92712.1 ALP92712.1 ALP92721.1 ALP92721.1 ALP92741.1 ALP92741.1 ALP92748.1 ALP92748.1 ALP92776.1 ALP92776.1 ALP92787.1 ALP92787.1 ALP92794.1 ALP92794.1 ALP92801.1 ALP92801.1 ALP92803.1 ALP92803.1 ALP92804.1 ALP92804.1 ALP92810.1 ALP92810.1 ALP92820.1 ALP92820.1 ALP92829.1 ALP92829.1 ALP92839.1 ALP92839.1 ALP92840.1 ALP92840.1 ALP92921.1 ALP92921.1 recD2-2 recD2-2 uvrA uvrA uvrB uvrB ALP92949.1 ALP92949.1 ALP92950.1 ALP92950.1 ALP92966.1 ALP92966.1 ALP92980.1 ALP92980.1 ALP93053.1 ALP93053.1 ALP93054.1 ALP93054.1 recR recR ALP93065.1 ALP93065.1 ALP93083.1 ALP93083.1 ALP93087.1 ALP93087.1 ALP93105.1 ALP93105.1 ALP93135.1 ALP93135.1 ALP93141.1 ALP93141.1 clpB clpB ALP93175.1 ALP93175.1 ALP93194.1 ALP93194.1 ALP93195.1 ALP93195.1 ALP93231.1 ALP93231.1 ALP93263.1 ALP93263.1 ALP93264.1 ALP93264.1 recG recG mprF mprF ALP93274.1 ALP93274.1 ALP93276.1 ALP93276.1 ALP93280.1 ALP93280.1 ALP93282.1 ALP93282.1 ALP93283.1 ALP93283.1 ALP93284.1 ALP93284.1 ALP93313.1 ALP93313.1 ALP93338.1 ALP93338.1 ALP93352.1 ALP93352.1 ALP93368.1 ALP93368.1 recO recO mutS2 mutS2 uvrC uvrC ALP93433.1 ALP93433.1 ALP93439.1 ALP93439.1 ALP93458.1 ALP93458.1 ALP93478.1 ALP93478.1 ALP93494.1 ALP93494.1 ALP93495.1 ALP93495.1 ALP93510.1 ALP93510.1 ALP93512.1 ALP93512.1 ALP93513.1 ALP93513.1 ALP93542.1 ALP93542.1 ALP93543.1 ALP93543.1 ALP93562.1 ALP93562.1 ALP93572.1 ALP93572.1 ALP93604.1 ALP93604.1 ALP93623.1 ALP93623.1 ALP93624.1 ALP93624.1 hcp hcp ALP93649.1 ALP93649.1 ALP93674.1 ALP93674.1 ALP93675.1 ALP93675.1 ALP93677.1 ALP93677.1 ALP93702.1 ALP93702.1 ALP93710.1 ALP93710.1 ALP93711.1 ALP93711.1 ALP93728.1 ALP93728.1 ALP93731.1 ALP93731.1 ALP93735.1 ALP93735.1 ALP93749.1 ALP93749.1 ALP93773.1 ALP93773.1 ALP93785.1 ALP93785.1 ALP93795.1 ALP93795.1 ALP93798.1 ALP93798.1 ALP93808.1 ALP93808.1 ALP93816.1 ALP93816.1 ALP93839.1 ALP93839.1 ALP93840.1 ALP93840.1 ALP93972.1 ALP93972.1 lon lon ALP94000.1 ALP94000.1 dacA dacA ALP94009.1 ALP94009.1 ALP94035.1 ALP94035.1 radA radA ALP94040.1 ALP94040.1 ALP94042.1 ALP94042.1 ligA-2 ligA-2 ALP94052.1 ALP94052.1 ALP94053.1 ALP94053.1 ruvB ruvB ruvA ruvA ruvC ruvC ALP94072.1 ALP94072.1 ALP94078.1 ALP94078.1 ALP94083.1 ALP94083.1 hprK hprK ALP94127.1 ALP94127.1 ung ung ALP94146.1 ALP94146.1 ALP94147.1 ALP94147.1 ALP94157.1 ALP94157.1 ALP94183.1 ALP94183.1 ALP94213.1 ALP94213.1 ALP94214.1 ALP94214.1 ALP94215.1 ALP94215.1 msrA msrA ALP94226.1 ALP94226.1 ALP94227.1 ALP94227.1 ALP94242.1 ALP94242.1 ALP94243.1 ALP94243.1 ALP94278.1 ALP94278.1 ALP94293.1 ALP94293.1 ALP94323.1 ALP94323.1 ALP94370.1 ALP94370.1 ALP94371.1 ALP94371.1 ALP94403.1 ALP94403.1 ALP94404.1 ALP94404.1 nth nth ALP94415.1 ALP94415.1 uppP uppP ALP94444.1 ALP94444.1 dinB dinB ALP94484.1 ALP94484.1 ALP94490.1 ALP94490.1 ALP94501.1 ALP94501.1 ALP94531.1 ALP94531.1 ALP94540.1 ALP94540.1 ALP94541.1 ALP94541.1 polA polA ALP94566.1 ALP94566.1 ALP94574.1 ALP94574.1 recA recA ALP94662.1 ALP94662.1 ALP94663.1 ALP94663.1 ALP94668.1 ALP94668.1 ALP94676.1 ALP94676.1 ALP94684.1 ALP94684.1 ALP94685.1 ALP94685.1 ALP94689.1 ALP94689.1 ALP94690.1 ALP94690.1 ALP94697.1 ALP94697.1 ALP94714.1 ALP94714.1 ALP94727.1 ALP94727.1 ALP94739.1 ALP94739.1 ALP94745.1 ALP94745.1 ALP94749.1 ALP94749.1 ALP94755.1 ALP94755.1 ALP94765.1 ALP94765.1 hcp-2 hcp-2 ALP94846.1 ALP94846.1 ALP94848.1 ALP94848.1 ALP94849.1 ALP94849.1 ALP94850.1 ALP94850.1 ALP94852.1 ALP94852.1 ALP94860.1 ALP94860.1 ALP94862.1 ALP94862.1 ALP94863.1 ALP94863.1 ALP94879.1 ALP94879.1 ALP94899.1 ALP94899.1 ALP94900.1 ALP94900.1 ALP94901.1 ALP94901.1 ALP94904.1 ALP94904.1 ALP94921.1 ALP94921.1 ALP94934.1 ALP94934.1 ALP94937.1 ALP94937.1 ALP94944.1 ALP94944.1 ALP94953.1 ALP94953.1 ALP94955.1 ALP94955.1 ALP94978.1 ALP94978.1 ALP94983.1 ALP94983.1 ALP94984.1 ALP94984.1 ALP94985.1 ALP94985.1 ALP95005.1 ALP95005.1 ALP95036.1 ALP95036.1 ALP95037.1 ALP95037.1 ALP95043.1 ALP95043.1 ALP95049.1 ALP95049.1 ALP95103.1 ALP95103.1 ALP95138.1 ALP95138.1 ALP95140.1 ALP95140.1 ALP95156.1 ALP95156.1 ALP95170.1 ALP95170.1 ALP95188.1 ALP95188.1 ALP95214.1 ALP95214.1 ALP95219.1 ALP95219.1 ALP95237.1 ALP95237.1 ALP95242.1 ALP95242.1 ALP95243.1 ALP95243.1 ALP95250.1 ALP95250.1 ALP95272.1 ALP95272.1 ALP95274.1 ALP95274.1 ALP95294.1 ALP95294.1 ALP95296.1 ALP95296.1 ALP95298.1 ALP95298.1 dnaJ dnaJ ALP95349.1 ALP95349.1 ychF ychF cas2 cas2 cas1 cas1 ALP95480.1 ALP95480.1 ALP95481.1 ALP95481.1 ALP95484.1 ALP95484.1 ALP95485.1 ALP95485.1 ALP95489.1 ALP95489.1 ALP95491.1 ALP95491.1 ALP95492.1 ALP95492.1 ALP95501.1 ALP95501.1 ALP95502.1 ALP95502.1 ALP95512.1 ALP95512.1 ALP95514.1 ALP95514.1 ALP95535.1 ALP95535.1 ALP95609.1 ALP95609.1 ALP95610.1 ALP95610.1 ALP95611.1 ALP95611.1 ALP95623.1 ALP95623.1 ALP95665.1 ALP95665.1 mfd mfd ALP95741.1 ALP95741.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
recFDNA recombination and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (367 aa)
ALP92415.1Methylated-D--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (156 aa)
lexASOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (224 aa)
ALP92435.1Transcriptional regulator, SARP family protein. (405 aa)
ALP92471.1Two-component response regulator. (98 aa)
ALP92496.1Alkyl hydroperoxide reductase protein C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
ALP92497.1Alkyl hydroperoxide reductase protein F. (540 aa)
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (673 aa)
recD2RecD-like DNA helicase YrrC; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (756 aa)
ALP92530.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter). (442 aa)
ALP92532.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter). (461 aa)
ALP92539.1Single-stranded-D-specific exonuclease RecJ. (705 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (865 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (646 aa)
ALP92636.1Methylated-D--protein-cysteine methyltransferase. (99 aa)
ALP92663.1Hypothetical protein; COG1496; Belongs to the multicopper oxidase YfiH/RL5 family. (270 aa)
ALP92679.14-hydroxybutanoyl-CoA dehydratase. (464 aa)
ALP92712.1Pyruvate:ferredoxin oxidoreductase, alpha subunit. (399 aa)
ALP92721.1Beta-lactamase. (253 aa)
ALP92741.1Sensor histidine kinase VanS. (380 aa)
ALP92748.1Pyridoxamine 5'-phosphate oxidase. (163 aa)
ALP92776.1Osmolarity sensory histidine kinase EnvZ. (357 aa)
ALP92787.1Sensory transduction histidine kinase. (196 aa)
ALP92794.1Exoenzymes regulatory protein AepA precursor. (206 aa)
ALP92801.1Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 like). (91 aa)
ALP92803.1Two-component response regulator. (230 aa)
ALP92804.1Phosphate regulon sensor protein PhoR (SphS). (470 aa)
ALP92810.1Transcriptional repressor for DNA biosynthesis. (171 aa)
ALP92820.1Hypothetical protein; Belongs to the sigma-70 factor family. (99 aa)
ALP92829.1Beta-lactamase. (263 aa)
ALP92839.1D-binding response regulator KdpE. (243 aa)
ALP92840.1Osmosensitive K+ channel histidine kinase KdpD. (356 aa)
ALP92921.1Hypothetical protein. (234 aa)
recD2-2RecD-like DNA helicase YrrC; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (746 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (941 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (655 aa)
ALP92949.1Sensory box/GGDEF family protein. (271 aa)
ALP92950.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter). (489 aa)
ALP92966.1Sulfonate ABC transporter, ATP-binding subunit SsuB. (196 aa)
ALP92980.1RNA polymerase sigma factor RpoE; Belongs to the sigma-70 factor family. ECF subfamily. (198 aa)
ALP93053.1Hypothetical protein. (549 aa)
ALP93054.1Phosphate regulon transcriptional regulatory protein PhoB (SphR). (222 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (200 aa)
ALP93065.1Hypothetical protein. (118 aa)
ALP93083.1Rubrerythrin. (198 aa)
ALP93087.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter). (457 aa)
ALP93105.1Modification methylase. (429 aa)
ALP93135.1Competence-specific transcriptional regulator. (111 aa)
ALP93141.1Hypothetical protein. (70 aa)
clpBClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (870 aa)
ALP93175.1Hypothetical protein. (238 aa)
ALP93194.1Regulation of D-alanyl-lipoteichoic acid biosynthesis, DltRNA. (225 aa)
ALP93195.1Sensor histidine kinase. (421 aa)
ALP93231.1Hypothetical protein. (68 aa)
ALP93263.1Hypothetical protein. (875 aa)
ALP93264.1Hypothetical protein. (753 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (687 aa)
mprFHypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (363 aa)
ALP93274.1Exodeoxyribonuclease III. (252 aa)
ALP93276.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (193 aa)
ALP93280.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter). (461 aa)
ALP93282.1Phosphate regulon transcriptional regulatory protein PhoB (SphR). (231 aa)
ALP93283.1Hypothetical protein. (699 aa)
ALP93284.1Thioredoxin reductase. (301 aa)
ALP93313.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (171 aa)
ALP93338.1D-3-methyladenine glycosylase II; Belongs to the DNA glycosylase MPG family. (194 aa)
ALP93352.1S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (154 aa)
ALP93368.1Recombination inhibitory protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (476 aa)
recODNA recombination and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (255 aa)
mutS2Recombination inhibitory protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (791 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (610 aa)
ALP93433.1D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (338 aa)
ALP93439.1Thioredoxin reductase. (282 aa)
ALP93458.1Hypothetical protein. (499 aa)
ALP93478.1Hypothetical protein. (404 aa)
ALP93494.1Regulatory protein, LuxR:Response regulator receiver. (205 aa)
ALP93495.1Hypothetical protein. (475 aa)
ALP93510.1Hypothetical protein. (422 aa)
ALP93512.1Hypothetical protein. (215 aa)
ALP93513.1Hypothetical protein. (398 aa)
ALP93542.1Sensor histidine kinase. (435 aa)
ALP93543.1Regulation of D-alanyl-lipoteichoic acid biosynthesis, DltRNA. (226 aa)
ALP93562.1Radical SAM domain protein. (295 aa)
ALP93572.1Endonuclease IV. (292 aa)
ALP93604.1D-cytosine methyltransferase. (522 aa)
ALP93623.1Two-component response regulator SA14-24. (233 aa)
ALP93624.1Sensor histidine kinase. (406 aa)
hcpHydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (532 aa)
ALP93649.1Thioredoxin reductase. (307 aa)
ALP93674.1Hypothetical protein. (42 aa)
ALP93675.1Transcriptional activator protein. (64 aa)
ALP93677.1Hypothetical protein. (45 aa)
ALP93702.1Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF). (372 aa)
ALP93710.1Regulation of D-alanyl-lipoteichoic acid biosynthesis, DltRNA. (222 aa)
ALP93711.1Sensor histidine kinase. (402 aa)
ALP93728.1Manganese superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (204 aa)
ALP93731.1Two-component response regulator. (235 aa)
ALP93735.1Sensor histidine kinase. (301 aa)
ALP93749.1Competence protein ComEC/Rec2. (346 aa)
ALP93773.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter). (448 aa)
ALP93785.1ClpB protein; Belongs to the ClpA/ClpB family. (819 aa)
ALP93795.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter). (443 aa)
ALP93798.14-carboxymuconolactone decarboxylase. (281 aa)
ALP93808.1Uracil-DNA glycosylase, family 4. (238 aa)
ALP93816.1Ethanolamine two-component response regulator. (179 aa)
ALP93839.1Regulation of D-alanyl-lipoteichoic acid biosynthesis, DltRNA. (250 aa)
ALP93840.1Sensor histidine kinase. (410 aa)
ALP93972.1DNA modification methyltransferase. (414 aa)
lonATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (802 aa)
ALP94000.1CarD-like transcriptional regulator. (158 aa)
dacAHypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (294 aa)
ALP94009.1Chaperone protein DnaJ. (201 aa)
ALP94035.1Phosphoglycolate phosphatase. (217 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (456 aa)
ALP94040.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter). (514 aa)
ALP94042.1Polypeptide composition of the spore coat protein CotJC. (198 aa)
ligA-2DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (658 aa)
ALP94052.1UPF0135 protein Bsu YqfO or Bsu YqfO NIF3/CutA domain. (266 aa)
ALP94053.1Hypothetical protein. (68 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (349 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (202 aa)
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (177 aa)
ALP94072.1N-acetyltransferase. (205 aa)
ALP94078.1DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (567 aa)
ALP94083.1Hypothetical protein; FIG01197514. (154 aa)
hprKHPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...] (317 aa)
ALP94127.1Hypothetical protein. (77 aa)
ungUracil-DNA glycosylase, family 1; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (228 aa)
ALP94146.1Rubrerythrin. (177 aa)
ALP94147.1Superoxide reductase. (123 aa)
ALP94157.1Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (115 aa)
ALP94183.1Catalase. (418 aa)
ALP94213.1Hypothetical protein. (145 aa)
ALP94214.1Hypothetical protein. (138 aa)
ALP94215.1Two-component response regulator. (183 aa)
msrAPeptide methionine sulfoxide reductase MsrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (372 aa)
ALP94226.1Transcriptional activator protein. (225 aa)
ALP94227.1Hypothetical protein. (383 aa)
ALP94242.1Sensor histidine kinase. (449 aa)
ALP94243.1Phosphate regulon transcriptional regulatory protein PhoB (SphR). (239 aa)
ALP94278.14-hydroxyphenylacetate 3-monooxygenase. (488 aa)
ALP94293.1Hypothetical protein. (1745 aa)
ALP94323.1Hypothetical protein. (442 aa)
ALP94370.1ATP-dependent nuclease, subunit A; ATP-dependent DNA helicase. (1205 aa)
ALP94371.1ATP-dependent nuclease, subunit B; ATP-dependent DNA helicase. (1116 aa)
ALP94403.1D-binding response regulator, AraC family. (355 aa)
ALP94404.1Methyl-accepting chemotaxis protein. (407 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (214 aa)
ALP94415.1Chloramphenicol acetyltransferase. (208 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (281 aa)
ALP94444.1ClpB protein; Belongs to the ClpA/ClpB family. (834 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (421 aa)
ALP94484.1Multimodular transpeptidase-transglycosylase. (901 aa)
ALP94490.1Hypothetical protein. (98 aa)
ALP94501.1PAP2 family protein. (185 aa)
ALP94531.1Carbon starvation protein A. (503 aa)
ALP94540.1Two-component response regulator yycF. (231 aa)
ALP94541.1Phosphate regulon sensor protein PhoR (SphS). (469 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (882 aa)
ALP94566.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter). (478 aa)
ALP94574.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (159 aa)
recARecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (370 aa)
ALP94662.1Phosphate regulon sensor protein PhoR (SphS). (469 aa)
ALP94663.1Two-component response regulator. (229 aa)
ALP94668.1Multi antimicrobial extrusion protein (Na(+)/drug antiporter). (444 aa)
ALP94676.1Hypothetical protein. (357 aa)
ALP94684.1Two-component sensor kinase yesM. (599 aa)
ALP94685.1Two-component response regulator yesN. (526 aa)
ALP94689.1Putative two-component system response regulator. (226 aa)
ALP94690.1Hypothetical protein. (429 aa)
ALP94697.1Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (165 aa)
ALP94714.1Enoyl reductase. (313 aa)
ALP94727.1Hypothetical protein. (582 aa)
ALP94739.1Hypothetical protein. (487 aa)
ALP94745.1UPF0246 protein YaaA; Belongs to the UPF0246 family. (247 aa)
ALP94749.1D-binding response regulator, LuxR family. (200 aa)
ALP94755.1Ethanolamine two-component response regulator. (194 aa)
ALP94765.1Sarcosine oxidase alpha subunit. (418 aa)
hcp-2Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (546 aa)
ALP94846.1CRISPR-associated helicase Cas3. (139 aa)
ALP94848.1D-binding response regulator, OmpR family. (170 aa)
ALP94849.1Sensor histidine kinase. (223 aa)
ALP94850.1Two-component hybrid sensor and regulator. (241 aa)
ALP94852.1Sensory box histidine kinase/response regulator. (848 aa)
ALP94860.1Very-short-patch mismatch repair endonuclease (G-T specific). (137 aa)
ALP94862.1D-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (368 aa)
ALP94863.1Hypothetical protein. (278 aa)
ALP94879.1Hypothetical protein. (79 aa)
ALP94899.1Two-component response regulator. (233 aa)
ALP94900.1Hypothetical protein. (691 aa)
ALP94901.1GGDEF domain. (308 aa)
ALP94904.1Hypothetical protein. (98 aa)
ALP94921.18-oxoguanine DNA glycosylase. (265 aa)
ALP94934.1Sensory box histidine kinase/response regulator. (861 aa)
ALP94937.1Response regulator. (131 aa)
ALP94944.1Protein from bacterioferritin family. (188 aa)
ALP94953.1Transcriptional regulator, AsnC family. (152 aa)
ALP94955.1Hypothetical protein. (430 aa)
ALP94978.1Stage 0 sporulation two-component response regulator (Spo0A); May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (256 aa)
ALP94983.1Phosphate regulon sensor protein PhoR (SphS). (489 aa)
ALP94984.1Two-component response regulator. (228 aa)
ALP94985.1Late competence protein ComEA, D receptor. (118 aa)
ALP95005.1Rubrerythrin. (180 aa)
ALP95036.1Phosphate regulon sensor protein PhoR (SphS). (425 aa)
ALP95037.1Phosphate regulon transcriptional regulatory protein PhoB (SphR). (222 aa)
ALP95043.1Phosphoglycolate phosphatase. (216 aa)
ALP95049.1Hypothetical protein. (144 aa)
ALP95103.1Type I restriction-modification system, restriction subunit R. (258 aa)
ALP95138.1D-binding response regulator. (229 aa)
ALP95140.1Sensor histidine kinase. (482 aa)
ALP95156.1Hypothetical protein. (46 aa)
ALP95170.1NPQTN specific sortase B. (279 aa)
ALP95188.1D-cytosine methyltransferase. (68 aa)
ALP95214.1Modification methylase Cfr9I; Belongs to the N(4)/N(6)-methyltransferase family. (318 aa)
ALP95219.1Hypothetical protein; FIG00529559. (41 aa)
ALP95237.1Prophage antirepressor. (295 aa)
ALP95242.1Hypothetical protein. (69 aa)
ALP95243.1RNA polymerase sigma-54 factor RpoN; Belongs to the sigma-70 factor family. ECF subfamily. (182 aa)
ALP95250.1Putative regulatory protein. (173 aa)
ALP95272.1RNA polymerase sigma factor SigV; Belongs to the sigma-70 factor family. ECF subfamily. (158 aa)
ALP95274.1A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (353 aa)
ALP95294.1Phosphate regulon sensor protein PhoR (SphS). (593 aa)
ALP95296.1Two-component response regulator SA14-24. (235 aa)
ALP95298.1Hypothetical protein. (167 aa)
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (386 aa)
ALP95349.1Two-component response regulator. (249 aa)
ychFGTP-binding and nucleic acid-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (388 aa)
cas2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (96 aa)
cas1CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (343 aa)
ALP95480.1CRISPR-associated RecB family exonuclease Cas4b; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (115 aa)
ALP95481.1CRISPR-associated RecB family exonuclease Cas4b. (61 aa)
ALP95484.1CRISPR-associated protein, CT1134 family. (242 aa)
ALP95485.1CRISPR-associated helicase Cas3. (796 aa)
ALP95489.1Vancomycin response regulator VanR. (263 aa)
ALP95491.1Domain often clustered or fused with uracil-D glycosylase. (256 aa)
ALP95492.1Biotin synthase. (423 aa)
ALP95501.1Hypothetical protein. (414 aa)
ALP95502.1D-binding response regulator. (226 aa)
ALP95512.1Hypothetical protein. (282 aa)
ALP95514.1Hypothetical protein. (86 aa)
ALP95535.1Hypothetical protein. (75 aa)
ALP95609.1Sensory box histidine kinase/response regulator. (819 aa)
ALP95610.1Hypothetical protein. (122 aa)
ALP95611.1Metal dependent phosphohydrolase; TIGR00254; pfam13487. (425 aa)
ALP95623.1RNA polymerase sigma factor SigV; Belongs to the sigma-70 factor family. ECF subfamily. (168 aa)
ALP95665.1Hypothetical protein. (64 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1169 aa)
ALP95741.1Hypothetical protein. (98 aa)
Your Current Organism:
Intestinimonas butyriciproducens
NCBI taxonomy Id: 1297617
Other names: CCUG 63529, Candidatus Clostridium anorexicus, DSM 26588, I. butyriciproducens, Intestinimonas butyriciproducens Klaring et al. 2013, Pseudoflavonifractor sp. 2-1.1, Pseudoflavonifractor sp. SRB-521-5-I, strain SRB-521-5-I
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