STRINGSTRING
TST_0952 TST_0952 rfbA rfbA coaD coaD dnaX dnaX rpoZ rpoZ TST_0426 TST_0426 pcnB pcnB rpoN rpoN pnp pnp TST_0492 TST_0492 nadM nadM nadD nadD TST_0552 TST_0552 TST_0563 TST_0563 fliA fliA TST_0677 TST_0677 TST_0679 TST_0679 cca cca TST_0691 TST_0691 ribF ribF TST_0884 TST_0884 cobP cobP glmU glmU rimN rimN TST_1105 TST_1105 TST_1115 TST_1115 galU galU thiI thiI galT galT gmpP gmpP kdsB kdsB TST_1236 TST_1236 TST_1292 TST_1292 TST_1293 TST_1293 dpx dpx dacA dacA TST_1376 TST_1376 rph rph rpoA rpoA rpoC rpoC rpoB rpoB neuA neuA cdsA cdsA TST_1562 TST_1562 TST_1569 TST_1569 moeB moeB dnaE dnaE TST_1741 TST_1741 cysN cysN TST_0256 TST_0256 glnD glnD dnaG dnaG holA holA mobA mobA TST_0072 TST_0072 TST_0052 TST_0052 dnaN dnaN
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
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TST_0952Signal transduction protein; Cache_1/GGDEF domain protein. (510 aa)
rfbAGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (499 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (76 aa)
TST_0426Hypothetical protein; Similar to N-terminus of DNA polymerase III subunit delta' HolB EC:2.7.7.7. (294 aa)
pcnBpoly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (459 aa)
rpoNRNA polymerase sigma-54 factor. (398 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (734 aa)
TST_0492Hypothetical protein. (712 aa)
nadMNicotinamide-nucleotide adenylyltransferase. (177 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (228 aa)
TST_0552Signal transduction protein; HAMP/GGDEF domain protein. (701 aa)
TST_0563Signal transduction protein; Diguanylate cyclase DgcB, GGDEF domain protein. (355 aa)
fliARNA polymerase sigma factor for flagellar operon FliA; Belongs to the sigma-70 factor family. (233 aa)
TST_0677Signal transduction protein; GGDEF domain protein. (332 aa)
TST_0679Signal transduction protein; GGDEF domain protein. (329 aa)
ccatRNA nucleotidyltransferase; CCA-adding enzyme. (872 aa)
TST_0691GGDEF domain protein. (72 aa)
ribFRiboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (317 aa)
TST_0884CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (425 aa)
cobPAdenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase. (167 aa)
glmUBifunctional UDP-N-acetylglucosamine pyrophosphorylase/Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (463 aa)
rimNtRNA threonylcarbamoyladenosine biosynthesis protein; Belongs to the SUA5 family. (210 aa)
TST_1105Signal transduction protein; Diguanylate cyclase, GGDEF domain. (354 aa)
TST_1115Signal transduction protein; Diguanylate cyclase, GGDEF domain. (330 aa)
galUUTP--glucose-1-phosphate uridylyltransferase. (286 aa)
thiIThiamine biosynthesis protein ThiI; N-terminus of KUP system potassium uptake protein. (388 aa)
galTUDPglucose--hexose-1-phosphate uridylyltransferase. (344 aa)
gmpPMannose-1-phosphate guanylyltransferase. (828 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (241 aa)
TST_1236Signal transduction protein; Diguanylate cyclase DgcB, GGDEF domain protein. (443 aa)
TST_1292D-beta-D-heptose 1-phosphate adenosyltransferase; C-terminus of RfaE bifunctional protein. (163 aa)
TST_1293D-beta-D-heptose 7-phosphate kinase; N-terminus of RfaE bifunctional protein. (337 aa)
dpxDNA polymerase, family X. (572 aa)
dacAConserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria; Belongs to the adenylate cyclase family. DacA/CdaA subfamily. (261 aa)
TST_1376Conserved hypothetical protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein [...] (875 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (249 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (331 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1443 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1394 aa)
neuAN-acylneuraminate cytidylyltransferase. (231 aa)
cdsAPhosphatidate cytidylyltransferase; Belongs to the CDS family. (252 aa)
TST_1562CBS domain-containing protein. (618 aa)
TST_1569Signal transduction protein; Diguanylate cyclase DgcB, GGDEF domain protein. (360 aa)
moeBAdenylyltransferase and sulfurtransferase. (243 aa)
dnaEDNA polymerase III subunit alpha. (1151 aa)
TST_1741Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. (459 aa)
cysNSulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (513 aa)
TST_0256Conserved hypothetical protein; Similar to N-terminuso of mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase RfbM EC:2.7.7.22 EC:5.3.1.8. (199 aa)
glnD[protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (850 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (560 aa)
holADNA polymerase III subunit delta. (323 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (202 aa)
TST_0072Conserved hypothetical protein. (286 aa)
TST_0052tRNA-specific 2-thiouridylase. (318 aa)
dnaNDNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (384 aa)
Your Current Organism:
Thermosulfidibacter takaii
NCBI taxonomy Id: 1298851
Other names: T. takaii ABI70S6, Thermosulfidibacter takaii ABI70S6
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