STRINGSTRING
TST_0009 TST_0009 pbuG pbuG TST_0059 TST_0059 pstB pstB kefA kefA secA secA tatA tatA modB modB modC modC TST_0093 TST_0093 TST_0125 TST_0125 TST_0129 TST_0129 TST_0138 TST_0138 fadL fadL nuoA nuoA nuoB nuoB nuoC-2 nuoC-2 nuoF nuoF nuoG nuoG TST_0207 TST_0207 nuoK nuoK TST_0209 TST_0209 TST_0210 TST_0210 nuoN nuoN TST_0232 TST_0232 TST_0233 TST_0233 TST_0236 TST_0236 TST_0238 TST_0238 TST_0245 TST_0245 TST_0246 TST_0246 TST_0247 TST_0247 trkA trkA TST_0290 TST_0290 TST_0291 TST_0291 TST_0294 TST_0294 TST_0299 TST_0299 mgtE mgtE secD secD secF secF TST_0407 TST_0407 yrbG yrbG lolD lolD msbA msbA atpB atpB atpE atpE trkH trkH TST_0536 TST_0536 TST_0548 TST_0548 mviN mviN fliI fliI motA motA znuC znuC TST_0721 TST_0721 TST_0734 TST_0734 crcB crcB atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH atpF atpF atpF-2 atpF-2 secG secG TST_0929 TST_0929 cbiB cbiB TST_0966 TST_0966 TST_0986 TST_0986 rodA rodA TST_1062 TST_1062 TST_1084 TST_1084 TST_1085 TST_1085 TST_1086 TST_1086 cbiQ cbiQ TST_1142 TST_1142 TST_1143 TST_1143 tatC tatC tatA-2 tatA-2 TST_1216 TST_1216 TST_1246 TST_1246 TST_1250 TST_1250 TST_1251 TST_1251 TST_1252 TST_1252 TST_1307 TST_1307 TST_1315 TST_1315 TST_1335 TST_1335 focA focA TST_1371 TST_1371 TST_1377 TST_1377 TST_1380 TST_1380 macA macA TST_1382 TST_1382 TST_1396 TST_1396 secY secY secE secE TST_1461 TST_1461 nuoN-2 nuoN-2 TST_1503 TST_1503 TST_1504 TST_1504 TST_1506 TST_1506 nuoC nuoC nuoB-2 nuoB-2 nuoA-2 nuoA-2 cobQ cobQ TST_1550 TST_1550 TST_1564 TST_1564 TST_1587 TST_1587 TST_1592 TST_1592 TST_1593 TST_1593 TST_1613 TST_1613 ppa ppa TST_1625 TST_1625 livM livM livH livH arsA arsA cstA cstA pal pal TST_1688 TST_1688 TST_1689 TST_1689 TST_1759 TST_1759 TST_1760 TST_1760 TST_1761 TST_1761
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TST_0009Ammonium transporter, Amt family. (406 aa)
pbuGMFS transporter, AGZA family, xanthine/uracil permease. (418 aa)
TST_0059Conserved hypothetical protein. (288 aa)
pstBPhosphate transport system ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (262 aa)
kefAHypothetical protein. (730 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (899 aa)
tatASec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (61 aa)
modBMolybdate transport system permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (228 aa)
modCMolybdate transport system ATP-binding protein. (341 aa)
TST_0093Inorganic phosphate transporter, PiT family. (412 aa)
TST_0125Porin; Belongs to the OprB family. (508 aa)
TST_0129Iron complex transport system permease; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (325 aa)
TST_0138Transporter. (474 aa)
fadLLong-chain fatty acid transport protein. (484 aa)
nuoANADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (118 aa)
nuoBNADH-quinone oxidoreductase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
nuoC-2NADH-quinone oxidoreductase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (556 aa)
nuoFNADH-quinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (423 aa)
nuoGNADH-quinone oxidoreductase subunit G. (739 aa)
TST_0207NADH-quinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (161 aa)
nuoKNADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (99 aa)
TST_0209NADH-quinone oxidoreductase subunit L. (631 aa)
TST_0210NADH-quinone oxidoreductase subunit M. (522 aa)
nuoNNADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (473 aa)
TST_0232Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (710 aa)
TST_0233Porin; Belongs to the OprB family. (473 aa)
TST_0236Peptidylprolyl isomerase; TonB-dependent receptor. (669 aa)
TST_0238Biopolymer transport protein. (185 aa)
TST_0245Outer membrane channel protein TolC. (432 aa)
TST_0246RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (374 aa)
TST_0247RND family efflux transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1032 aa)
trkATrk system potassium uptake protein TrkA. (224 aa)
TST_0290Biopolymer transport protein ExbD/TolR. (132 aa)
TST_0291Biopolymer transport protein ExbB. (187 aa)
TST_0294Sodium:neurotransmitter symporter, NSS family. (516 aa)
TST_0299Conserved hypothetical protein. (351 aa)
mgtEMagnesium transporter, MgtE family; Acts as a magnesium transporter. (448 aa)
secDPreprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (515 aa)
secFPreprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (312 aa)
TST_0407Peptide/nickel transport system substrate-binding protein. (531 aa)
yrbGNa+:Ca+ antiporter, CaCA family. (315 aa)
lolDLipoprotein-releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. (222 aa)
msbAATP-binding cassette, subfamily B, bacterial MsbA. (577 aa)
atpBF-type H+-transporting ATPase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (221 aa)
atpEConserved hypothetical protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (120 aa)
trkHTrk system potassium uptake protein TrkH. (444 aa)
TST_0536Peptide/nickel transport system permease. (324 aa)
TST_0548Peptide/nickel transport system permease. (276 aa)
mviNVirulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (515 aa)
fliIFlagellum-specific ATP synthase. (448 aa)
motAChemotaxis protein MotA. (254 aa)
znuCZinc transport system ATP-binding protein. (243 aa)
TST_0721Sodium:aspartate transporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (394 aa)
TST_0734Lysine exporter protein LysE/YggA. (209 aa)
crcBCamphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (135 aa)
atpCF-type H+-transporting ATPase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (133 aa)
atpDF-type H+-transporting ATPase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (472 aa)
atpGF-type H+-transporting ATPase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (291 aa)
atpAF-type H+-transporting ATPase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (502 aa)
atpHF-type H+-transporting ATPase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (179 aa)
atpFF-type H+-transporting ATPase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (185 aa)
atpF-2F-type H+-transporting ATPase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (145 aa)
secGPreprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (137 aa)
TST_0929Chloride channel protein, CIC family. (593 aa)
cbiBAdenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (305 aa)
TST_0966Chloride channel protein, CIC family. (595 aa)
TST_0986Pseudogene. citrate transporter. (175 aa)
rodARod shape determining protein RodA; Belongs to the SEDS family. (358 aa)
TST_1062MscS mechanosensitive ion channel. (395 aa)
TST_1084MFS transporter, DHA2 family, multidrug resistance protein B; Belongs to the major facilitator superfamily. (519 aa)
TST_1085Multidrug resistance protein A. (387 aa)
TST_1086Outer membrane factor, OMF family. (462 aa)
cbiQCobalt/nickel transport system permease. (213 aa)
TST_1142Cobalt/nickel transport system permease. (98 aa)
TST_1143Cobalt/nickel transport system permease. (210 aa)
tatCSec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. (279 aa)
tatA-2Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (65 aa)
TST_1216Ion transporter; Probable gene remnant. hypothetical protein. (365 aa)
TST_1246MFS transporter, DHA2 family, multidrug resistance protein B; Belongs to the major facilitator superfamily. (515 aa)
TST_1250HlyD family secretion protein. (351 aa)
TST_1251Multidrug resistance protein A. (363 aa)
TST_1252Outer membrane factor, OMF family. (445 aa)
TST_1307Conserved hypothetical protein. (254 aa)
TST_1315Conserved hypothetical protein. (154 aa)
TST_1335Bile acid:Na+ symporter, ACR3 family. (312 aa)
focAFormate uptake permease. (346 aa)
TST_1371OmpA-OmpF porin, OOP family. (384 aa)
TST_1377Lactate transporter, LctP family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (528 aa)
TST_1380ABC transport system ATP-binding protein. (224 aa)
macAMacrolide-specific efflux protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (394 aa)
TST_1382Outer membrane channel protein. (417 aa)
TST_1396General secretion pathway protein J. (182 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (434 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (63 aa)
TST_1461Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (720 aa)
nuoN-2NADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (484 aa)
TST_1503NADH-quinone oxidoreductase subunit M. (537 aa)
TST_1504NADH-quinone oxidoreductase subunit L. (663 aa)
TST_1506NADH-quinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (172 aa)
nuoCNADH-quinone oxidoreductase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. (171 aa)
nuoB-2NADH-quinone oxidoreductase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (158 aa)
nuoA-2NADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (121 aa)
cobQAdenosylcobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (477 aa)
TST_1550GPR1/FUN34/yaaH family protein. (192 aa)
TST_1564solute:Na+ symporter, SSS family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (534 aa)
TST_1587TrkA domain-containing protein. (351 aa)
TST_1592Conserved hypothetical protein. (89 aa)
TST_1593Conserved hypothetical protein. (440 aa)
TST_1613Arsenite transporter, ACR3 family. (344 aa)
ppaPutative K(+)-stimulated pyrophosphate-energized sodium pump; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily. (662 aa)
TST_1625Conserved hypothetical protein. (288 aa)
livMBranched-chain amino acid transport system permease; Belongs to the binding-protein-dependent transport system permease family. (320 aa)
livHBranched-chain amino acid transport system permease; Belongs to the binding-protein-dependent transport system permease family. (284 aa)
arsAArsenite-transporting ATPase. (305 aa)
cstACarbon starvation protein. (574 aa)
palPeptidoglycan-associated lipoprotein; Belongs to the Pal lipoprotein family. (187 aa)
TST_1688Biopolymer transport protein ExbD. (131 aa)
TST_1689Biopolymer transport protein ExbB. (212 aa)
TST_1759Outer membrane efflux protein. (450 aa)
TST_1760RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (383 aa)
TST_1761RND family efflux transporter inner membrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1080 aa)
Your Current Organism:
Thermosulfidibacter takaii
NCBI taxonomy Id: 1298851
Other names: T. takaii ABI70S6, Thermosulfidibacter takaii ABI70S6
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.