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| | plsY | Glycerol-3-phosphate acyltransferase PlsY; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (197 aa) |
| | TST_0107 | 3-hydroxypropionyl-coenzyme A dehydratase; 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase PaaG EC:5.3.3.18. (259 aa) |
| | TST_0117 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (198 aa) |
| | TST_0153 | Glycosyl transferase, family 9. (322 aa) |
| | fadN | 3-hydroxyacyl-CoA dehydrogenase. (794 aa) |
| | fadA | acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | ispDF | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (376 aa) |
| | TST_0242 | Conserved hypothetical protein. (303 aa) |
| | TST_0258 | Glycosyl transferase, group 1. (353 aa) |
| | kdsC | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; KDO 8-P phosphatase. (171 aa) |
| | TST_0460 | Glycosyl transferase, family 39. (452 aa) |
| | lpxB | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (354 aa) |
| | TST_0469 | Conserved hypothetical protein. (262 aa) |
| | TST_0470 | Hypothetical protein. (225 aa) |
| | lpxC | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (285 aa) |
| | TST_0544 | Hypothetical protein. (401 aa) |
| | plsC | 1-acyl-sn-glycerol-3-phosphate acyltransferase. (244 aa) |
| | TST_0656 | acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | TST_0657 | 3-hydroxybutyryl-CoA dehydrogenase. (289 aa) |
| | TST_0658 | Hypothetical protein; Similar to 3-hydroxybutyryl-CoA dehydratase Crt EC:4.2.1.55. (248 aa) |
| | TST_0669 | Glycosyl transferase, family 39; Similar to 4-amino-4-deoxy-L-arabinose transferase ArnT EC:2.4.2.43. (453 aa) |
| | ispB | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. (321 aa) |
| | TST_0719 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (186 aa) |
| | TST_0723 | 3-oxoacyl-[acyl-carrier protein] reductase. (246 aa) |
| | gcpE | (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (360 aa) |
| | TST_0843 | 3-hydroxybutyryl-CoA dehydratase. (248 aa) |
| | TST_0883 | Myo-inositol-1-phosphate synthase. (394 aa) |
| | TST_0884 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (425 aa) |
| | lpxA | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (261 aa) |
| | TST_0924 | 3-oxoacyl-[acyl-carrier-protein] synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (386 aa) |
| | TST_0950 | 3-hydroxybutyryl-CoA dehydratase. (270 aa) |
| | TST_0951 | 3-hydroxybutyryl-CoA dehydrogenase. (282 aa) |
| | glmU | Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (463 aa) |
| | TST_0969 | enoyl-CoA hydratase/isomerase. (261 aa) |
| | TST_0975 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (177 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (324 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (341 aa) |
| | TST_1026 | 3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (250 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (351 aa) |
| | TST_1063 | acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | TST_1134 | Phospholipase D/Transphosphatidylase. (174 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase; KDO 8-P synthase; Belongs to the KdsA family. (275 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (241 aa) |
| | pssA | Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (240 aa) |
| | psd | Phosphatidylserine decarboxylase. (201 aa) |
| | TST_1298 | Lipopolysaccharide biosynthesis protein. (290 aa) |
| | TST_1325 | 3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (410 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (84 aa) |
| | TST_1327 | 3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (243 aa) |
| | fabD | [acyl-carrier-protein] S-malonyltransferase. (306 aa) |
| | fabH | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (326 aa) |
| | plsX | Glycerol-3-phosphate acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (364 aa) |
| | TST_1353 | 3-oxoacyl-[acyl-carrier protein] reductase. (254 aa) |
| | kdtA | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (428 aa) |
| | pycB | Pyruvate carboxylase subunit B. (173 aa) |
| | TST_1365 | acetyl-CoA carboxylase, biotin carboxylase subunit. (500 aa) |
| | accD | acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (284 aa) |
| | TST_1466 | Conserved hypothetical protein. (659 aa) |
| | dxr | 1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (380 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; Belongs to the CDS family. (252 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (289 aa) |
| | TST_1578 | acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (386 aa) |
| | TST_1579 | Conserved hypothetical protein; Similar to hydroxymethylglutaryl-CoA synthase EC:2.3.3.10. (351 aa) |
| | TST_1581 | enoyl-CoA hydratase/isomerase; Similar to methylglutaconyl-CoA hydratase EC:4.2.1.18. (258 aa) |
| | TST_1582 | acetyl-CoA carboxylase biotin carboxyl carrier protein. (71 aa) |
| | TST_1583 | acetyl-CoA carboxylase, biotin carboxylase subunit. (447 aa) |
| | uppS | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (236 aa) |
| | waaC | Heptosyltransferase I. (302 aa) |
| | TST_1663 | acetyl-CoA carboxylase, biotin carboxylase subunit. (443 aa) |
| | TST_1664 | acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (160 aa) |
| | fabZ | 3R-hydroxymyristoyl ACP dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa) |
| | lpxD | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (335 aa) |
| | accA | acetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | TST_1717 | Hypothetical protein; Glycosyl transferase family 39. (507 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (617 aa) |
| | ispA | Geranylgeranyl diphosphate synthase, type II; Belongs to the FPP/GGPP synthase family. (303 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (279 aa) |
| | waaF | Heptosyltransferase II. (332 aa) |
