STRINGSTRING
J056_003222 J056_003222 J056_002835 J056_002835 J056_002743 J056_002743 J056_002732 J056_002732 J056_002821 J056_002821 J056_002571 J056_002571 J056_002608 J056_002608 J056_002519 J056_002519 J056_002513 J056_002513 J056_002393 J056_002393 J056_001904 J056_001904 J056_001887 J056_001887 J056_002402 J056_002402 J056_002417 J056_002417 J056_001922 J056_001922 J056_001853 J056_001853 J056_002384 J056_002384 J056_001826 J056_001826 J056_001841 J056_001841 J056_001755 J056_001755 J056_001737 J056_001737 J056_001666 J056_001666 J056_001642 J056_001642 J056_001605 J056_001605 J056_001516 J056_001516 J056_001196 J056_001196 J056_001172 J056_001172 J056_001206 J056_001206 J056_001182 J056_001182 J056_001263 J056_001263 J056_001217 J056_001217 J056_001209 J056_001209 J056_001291 J056_001291 J056_001010 J056_001010 J056_001015 J056_001015 J056_001033 J056_001033 J056_001324 J056_001324 J056_001099 J056_001099 J056_001081 J056_001081 J056_001134 J056_001134 J056_000878 J056_000878 J056_000977 J056_000977 J056_000943 J056_000943 J056_000680 J056_000680 J056_000746 J056_000746 J056_000604 J056_000604 J056_000578 J056_000578 J056_000585 J056_000585 J056_003187 J056_003187 J056_004756 J056_004756 J056_004699 J056_004699 J056_004727 J056_004727 J056_002735 J056_002735 J056_004389 J056_004389 J056_004822 J056_004822 J056_004424 J056_004424 J056_002627 J056_002627 J056_004459 J056_004459 J056_004489 J056_004489 J056_004493 J056_004493 J056_004534 J056_004534 J056_004521 J056_004521 J056_004556 J056_004556 J056_004603 J056_004603 J056_004185 J056_004185 J056_004270 J056_004270 J056_004176 J056_004176 J056_001886 J056_001886 J056_001911 J056_001911 J056_001931 J056_001931 J056_003840 J056_003840 J056_003829 J056_003829 J056_001793 J056_001793 J056_003849 J056_003849 J056_003854 J056_003854 J056_004361 J056_004361 J056_003959 J056_003959 J056_001700 J056_001700 J056_003984 J056_003984 J056_003998 J056_003998 J056_004065 J056_004065 J056_003981 J056_003981 J056_004075 J056_004075 J056_004073 J056_004073 J056_004046 J056_004046 J056_003620 J056_003620 J056_003633 J056_003633 J056_001607 J056_001607 J056_003690 J056_003690 J056_001372 J056_001372 J056_003694 J056_003694 J056_001412 J056_001412 J056_003631 J056_003631 J056_003753 J056_003753 J056_000987 J056_000987 J056_000719 J056_000719 J056_003336 J056_003336 J056_003292 J056_003292 J056_003332 J056_003332 J056_000611 J056_000611 J056_003402 J056_003402 J056_003422 J056_003422 J056_004733 J056_004733 J056_004763 J056_004763 J056_004843 J056_004843 J056_004407 J056_004407 J056_003016 J056_003016 J056_004217 J056_004217 J056_003024 J056_003024 J056_004242 J056_004242 J056_003066 J056_003066 J056_003071 J056_003071 J056_003089 J056_003089 J056_003104 J056_003104 J056_003154 J056_003154 J056_003032 J056_003032 J056_002926 J056_002926 J056_002005 J056_002005 J056_004017 J056_004017 J056_001986 J056_001986 J056_002016 J056_002016 J056_003567 J056_003567 J056_002061 J056_002061 J056_002071 J056_002071 J056_003637 J056_003637 J056_003657 J056_003657 J056_002182 J056_002182 J056_002003 J056_002003 J056_002166 J056_002166 J056_002221 J056_002221 J056_002098 J056_002098 J056_002231 J056_002231 J056_002313 J056_002313 J056_000363 J056_000363 J056_000027 J056_000027 J056_000009 J056_000009 J056_000037 J056_000037 J056_000070 J056_000070 J056_000104 J056_000104 J056_000092 J056_000092 J056_000137 J056_000137 J056_000281 J056_000281 J056_000353 J056_000353 J056_000105 J056_000105 J056_003128 J056_003128 J056_003148 J056_003148 J056_003158 J056_003158 J056_002935 J056_002935 J056_002114 J056_002114 J056_002184 J056_002184 J056_000011 J056_000011 J056_000007 J056_000007 J056_000046 J056_000046 J056_000128 J056_000128 J056_000145 J056_000145 J056_000156 J056_000156
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
J056_003222NADP-specific glutamate dehydrogenase. (631 aa)
J056_002835NADH oxidase. (461 aa)
J056_002743Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (365 aa)
J056_002732Mannose-6-phosphate isomerase. (422 aa)
J056_002821Malate dehydrogenase. (341 aa)
J056_002571Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (367 aa)
J056_002608Uncharacterized protein. (989 aa)
J056_002519Putative phosphoglycerate mutase. (216 aa)
J056_002513Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (517 aa)
J056_002393Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (459 aa)
J056_001904Triosephosphate isomerase. (252 aa)
J056_001887Dihydroxy-acid dehydratase. (580 aa)
J056_002402Uncharacterized protein. (276 aa)
J056_002417Putative 2-hydroxyacid dehydrogenase UNK4.10; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
J056_001922Transket_pyr domain-containing protein. (1290 aa)
J056_001853Dihydrolipoyl dehydrogenase. (539 aa)
J056_002384Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (354 aa)
J056_001826Putative fumarate reductase. (631 aa)
J056_001841Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (446 aa)
J056_001755Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate; Belongs to the ArgJ family. (441 aa)
J056_001737Malic enzyme. (544 aa)
J056_001666Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (163 aa)
J056_001642Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (413 aa)
J056_001605Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (595 aa)
J056_001516Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (624 aa)
J056_001196Chorismate synthase. (414 aa)
J056_001172Ornithine aminotransferase. (428 aa)
J056_001206Stress-response A/B barrel domain-containing protein. (92 aa)
J056_001182Threonine synthase. (535 aa)
J056_001263Glyceraldehyde-3-phosphate dehydrogenase. (336 aa)
J056_001217Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (367 aa)
J056_001209Histidinol-phosphate aminotransferase. (396 aa)
J056_001291Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (267 aa)
J056_001010Uncharacterized protein. (210 aa)
J056_001015Ribose-5-phosphate isomerase; Belongs to the synaptobrevin family. (650 aa)
J056_001033Phosphotransferase. (454 aa)
J056_0013243-isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (374 aa)
J056_001099Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (472 aa)
J056_001081Malate synthase; Belongs to the malate synthase family. (530 aa)
J056_001134Metal tolerance protein 9. (459 aa)
J056_000878DNA repair protein RAD16. (868 aa)
J056_000977Histidine biosynthesis trifunctional protein. (846 aa)
J056_000943Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (505 aa)
J056_000680Arginase; Belongs to the arginase family. (309 aa)
J056_000746Putative oxidoreductase C1F5.03c. (394 aa)
J056_000604Uncharacterized protein. (170 aa)
J056_000578Threonine dehydratase. (527 aa)
J056_000585Pyruvate kinase; Belongs to the pyruvate kinase family. (467 aa)
J056_003187N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family. (861 aa)
J056_004756Formyltetrahydrofolate deformylase. (348 aa)
J056_004699Malate dehydrogenase. (333 aa)
J056_004727N-acetyltransferase domain-containing protein. (631 aa)
J056_002735Stress-response A/B barrel domain-containing protein. (103 aa)
J056_004389Tryptophan synthase. (708 aa)
J056_004822Uncharacterized protein. (182 aa)
J056_004424Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (600 aa)
J056_002627Citrate synthase; Belongs to the citrate synthase family. (458 aa)
J056_004459Homoserine kinase. (356 aa)
J056_004489Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (732 aa)
J056_004493Putative gamma-glutamyl phosphate reductase. (455 aa)
J056_004534Argininosuccinate synthase. (424 aa)
J056_004521Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (460 aa)
J056_004556D-amino-acid oxidase. (408 aa)
J056_004603Transketolase. (634 aa)
J056_004185Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1031 aa)
J056_004270Uncharacterized protein. (580 aa)
J056_004176Isocitrate lyase. (540 aa)
J056_001886ATP phosphoribosyltransferase. (277 aa)
J056_001911Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (324 aa)
J056_001931NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1065 aa)
J056_003840Putative oxidoreductase C1F5.03c. (398 aa)
J056_003829Uncharacterized protein. (589 aa)
J056_001793Putative carboxypeptidase. (397 aa)
J056_003849Putative aspartokinase. (566 aa)
J056_0038541-aminocyclopropane-1-carboxylate synthase-like protein 2. (465 aa)
J056_004361Putative NAD-dependent malic enzyme 3. (607 aa)
J056_003959Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (426 aa)
J056_001700ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (817 aa)
J056_003984Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (501 aa)
J056_0039986-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (284 aa)
J056_004065Enamine/imine deaminase. (142 aa)
J056_003981Phosphoserine aminotransferase. (392 aa)
J056_004075Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (688 aa)
J056_004073Fructose-2,6-bisphosphatase. (560 aa)
J056_004046D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (480 aa)
J056_003620Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (190 aa)
J056_003633Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (213 aa)
J056_001607Enolase. (444 aa)
J056_003690Homoserine dehydrogenase. (366 aa)
J056_001372Maltose fermentation regulatory protein MAL13. (283 aa)
J056_0036943-dehydroshikimate dehydratase. (1110 aa)
J056_001412Aspartate aminotransferase, cytoplasmic. (419 aa)
J056_003631Transaldolase. (349 aa)
J056_003753Putative argininosuccinate lyase. (462 aa)
J056_000987Apoptosis-inducing factor 2. (487 aa)
J056_000719Putative phosphoketolase. (842 aa)
J056_003336Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (778 aa)
J056_003292Fructose-1,6-bisphosphatase, cytosolic; Belongs to the FBPase class 1 family. (336 aa)
J056_003332Anthranilate synthase component 1. (504 aa)
J056_000611Glyoxylate reductase/hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (488 aa)
J056_003402UPF0012 hydrolase C26A3.11. (1390 aa)
J056_0034221-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (255 aa)
J056_0047336-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 4. (506 aa)
J056_0047633-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (760 aa)
J056_004843Anthranilate phosphoribosyltransferase. (361 aa)
J056_004407Putative low-specificity L-threonine aldolase. (392 aa)
J056_003016Uncharacterized protein. (308 aa)
J056_004217Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (327 aa)
J056_003024L-pipecolate oxidase. (429 aa)
J056_004242Chorismate mutase. (249 aa)
J056_003066Putative aspartate-semialdehyde dehydrogenase. (361 aa)
J056_003071Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (548 aa)
J056_003089Putative homoisocitrate dehydrogenase. (364 aa)
J056_003104Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (307 aa)
J056_003154Low-specificity L-threonine aldolase. (378 aa)
J056_003032Uncharacterized protein; Belongs to the DapA family. (306 aa)
J056_002926Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (754 aa)
J056_002005Sedoheptulose 1,7-bisphosphatase. (229 aa)
J056_004017Transket_pyr domain-containing protein. (1019 aa)
J056_001986ACT domain-containing protein. (327 aa)
J056_002016Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (429 aa)
J056_003567Branched-chain-amino-acid aminotransferase-like protein 1. (268 aa)
J056_002061Uncharacterized protein; Belongs to the ketol-acid reductoisomerase family. (390 aa)
J056_002071Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (372 aa)
J056_003637Lipoyl-binding domain-containing protein. (399 aa)
J056_003657Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (231 aa)
J056_002182Apoptosis-inducing factor-like protein A. (373 aa)
J056_002003ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1144 aa)
J056_002166PIPK domain-containing protein. (1800 aa)
J056_002221Glucose-6-phosphate isomerase; Belongs to the GPI family. (547 aa)
J056_002098Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (641 aa)
J056_002231Putative Xaa-Pro aminopeptidase P; Belongs to the peptidase M24B family. (647 aa)
J056_002313Phosphoenolpyruvate carboxykinase. (544 aa)
J056_0003636-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (493 aa)
J056_0000272-isopropylmalate synthase. (822 aa)
J056_000009Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (201 aa)
J056_000037Putative glutamate 5-kinase. (472 aa)
J056_000070Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1192 aa)
J056_000104Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (417 aa)
J056_000092Transketolase-like protein 2. (745 aa)
J056_000137Acetolactate synthase. (669 aa)
J056_000281Para-aminobenzoate synthase. (562 aa)
J056_000353Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
J056_000105Glutamate--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (465 aa)
J056_003128Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (368 aa)
J056_003148RING-type domain-containing protein. (220 aa)
J056_003158Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (314 aa)
J056_002935Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa)
J056_002114Glutamine synthetase. (357 aa)
J056_002184Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]; Belongs to the spermidine/spermine synthase family. (746 aa)
J056_000011Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (777 aa)
J056_000007Aminotran_1_2 domain-containing protein. (481 aa)
J056_000046Phosphotransferase. (504 aa)
J056_000128Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (420 aa)
J056_000145Lipoyl-binding domain-containing protein. (363 aa)
J056_000156Dihydroxy-acid dehydratase. (582 aa)
Your Current Organism:
Wallemia ichthyophaga
NCBI taxonomy Id: 1299270
Other names: W. ichthyophaga EXF-994, Wallemia ichthyophaga EXF-994
Server load: low (20%) [HD]