STRINGSTRING
I596_3129 I596_3129 I596_3030 I596_3030 I596_3085 I596_3085 I596_1021 I596_1021 I596_1099 I596_1099 I596_1134 I596_1134 I596_1160 I596_1160 I596_1162 I596_1162 slyX slyX I596_135 I596_135 hutU hutU I596_1377 I596_1377 I596_1378 I596_1378 hutI hutI I596_1813 I596_1813 I596_1821 I596_1821 I596_1872 I596_1872 I596_1898 I596_1898 I596_1915 I596_1915 tdh tdh I596_2150 I596_2150 I596_2169 I596_2169 I596_2211 I596_2211 I596_2246 I596_2246 I596_2321 I596_2321 I596_2426 I596_2426 I596_3021 I596_3021 I596_2599 I596_2599 I596_286 I596_286 I596_2907 I596_2907 I596_991 I596_991 I596_874 I596_874 hmgA hmgA kynA kynA I596_867 I596_867 prpB prpB gcvPA gcvPA gcvH gcvH gcvT gcvT nbaC nbaC kynU kynU kmo kmo dtd dtd I596_485 I596_485 I596_38 I596_38 anmK anmK I596_3583 I596_3583 I596_3495 I596_3495 speA speA I596_3449 I596_3449 I596_3384 I596_3384 gcvPB gcvPB I596_3317 I596_3317 I596_3193 I596_3193
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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I596_3129Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (405 aa)
I596_3030HIT family protein. (140 aa)
I596_3085Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1063 aa)
I596_1021Enoyl-CoA hydratase. (390 aa)
I596_1099Fumarylacetoacetate hydrolase family protein. (228 aa)
I596_1134Coenzyme F390 synthetase. (452 aa)
I596_1160Methylcrotonoyl-CoA carboxylase. (535 aa)
I596_11623-ketoacyl-CoA thiolase/Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
slyXSlyX family protein; Belongs to the SlyX family. (71 aa)
I596_1353-ketoacyl-CoA thiolase/Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (557 aa)
I596_13773-ketoacyl-CoA thiolase/Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
I596_13783-hydroxyacyl-CoA dehydrogenase. (790 aa)
hutIImidazolonepropionase. (414 aa)
I596_1813N-formylglutamate amidohydrolase. (260 aa)
I596_1821Alanine dehydrogenase. (353 aa)
I596_1872Ferredoxin subunit of nitrite reductase and ring-hydroxylating dioxygenase. (104 aa)
I596_1898Histidine ammonia-lyase. (667 aa)
I596_1915Hydroxymethylglutaryl-CoA lyase. (300 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (340 aa)
I596_2150Lysyl-lysine 2,3-aminomutase. (334 aa)
I596_2169Putative LmbE-like protein. (336 aa)
I596_2211Hydroxymethylglutaryl-CoA lyase. (309 aa)
I596_2246Putative Xaa-Pro aminopeptidase. (433 aa)
I596_2321Thioesterase superfamily protein. (170 aa)
I596_2426HIT family hydrolase, diadenosine tetraphosphate hydrolase. (114 aa)
I596_3021NADH:flavin oxidoreductase. (672 aa)
I596_2599Amidohydrolase. (433 aa)
I596_286Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin. (237 aa)
I596_2907Amidohydrolase. (1097 aa)
I596_991D-amino acid dehydrogenase small subunit. (417 aa)
I596_874Fumarylacetoacetate (FAA) hydrolase. (333 aa)
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (435 aa)
kynATryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (285 aa)
I596_867Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit. (326 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (298 aa)
gcvPAGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (454 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (131 aa)
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (362 aa)
nbaC3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (175 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (428 aa)
kmo2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (469 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (146 aa)
I596_485Enoyl-CoA hydratase. (682 aa)
I596_38Putative hydrolase of the alpha/beta-hydrolase fold protein. (336 aa)
anmKAnhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (366 aa)
I596_3583Amidohydrolase 3. (613 aa)
I596_3495Phenylalanine-4-hydroxylase. (296 aa)
speABiosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (628 aa)
I596_3449Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (402 aa)
I596_3384Histidine ammonia-lyase. (514 aa)
gcvPBGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (487 aa)
I596_3317NAD-glutamate dehydrogenase. (1646 aa)
I596_3193Putative hydrolase. (620 aa)
Your Current Organism:
Dokdonella koreensis
NCBI taxonomy Id: 1300342
Other names: D. koreensis DS-123, Dokdonella koreensis DS-123
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