(24 nodes) Pyridoxal phosphate-dependent transferase, small domain network (Dokdonella koreensis)

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Your Input:
	I596_3785	Cystathionine beta-lyase/cystathionine gamma-synthase. (386 aa)
	I596_1470	Methionine aminotransferase. (383 aa)
	I596_1563	Alanine-glyoxylate aminotransferase apoenzyme. (372 aa)
	serC	Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (360 aa)
	hisC	Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (370 aa)
	I596_1715	Cystathionine gamma-synthase. (388 aa)
	I596_1787	Transcriptional regulator, GntR family. (546 aa)
	I596_1861	Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (411 aa)
	kbl	2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (420 aa)
	I596_26	Threonine aldolase. (337 aa)
	bioA	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (452 aa)
	I596_2871	Transcriptional regulator, GntR family. (493 aa)
	I596_3075	Class I and II aminotransferase. (398 aa)
	I596_3196	Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (502 aa)
	gcvPB	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (487 aa)
	hisC-2	Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (349 aa)
	bioF	8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (389 aa)
	I596_3793	Aminotransferase AlaT. (417 aa)
	glyA	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
	kynU	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (428 aa)
	gcvPA	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (454 aa)
	I596_736	Cystathionine gamma-synthase. (397 aa)
	argD	Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (412 aa)
	hemL	Glutamate-1-semialdehyde 2,1-aminomutase. (428 aa)

Your Current Organism:

Dokdonella koreensis

NCBI taxonomy Id: 1300342
Other names: D. koreensis DS-123, Dokdonella koreensis DS-123

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I596_1563	I596_26	I596_1563	I596_26	Alanine-glyoxylate aminotransferase apoenzyme.	Threonine aldolase.	0.931
I596_1563	I596_3793	I596_1563	I596_3793	Alanine-glyoxylate aminotransferase apoenzyme.	Aminotransferase AlaT.	0.926
I596_1563	gcvPA	I596_1563	I596_710	Alanine-glyoxylate aminotransferase apoenzyme.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	0.902
I596_1563	gcvPB	I596_1563	I596_3359	Alanine-glyoxylate aminotransferase apoenzyme.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.917
I596_1563	glyA	I596_1563	I596_630	Alanine-glyoxylate aminotransferase apoenzyme.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.939
I596_1563	kbl	I596_1563	I596_2038	Alanine-glyoxylate aminotransferase apoenzyme.	2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.	0.910
I596_1861	I596_736	I596_1861	I596_736	Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.	Cystathionine gamma-synthase.	0.900
I596_26	I596_1563	I596_26	I596_1563	Threonine aldolase.	Alanine-glyoxylate aminotransferase apoenzyme.	0.931
I596_26	gcvPA	I596_26	I596_710	Threonine aldolase.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	0.919
I596_26	gcvPB	I596_26	I596_3359	Threonine aldolase.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.921
I596_26	glyA	I596_26	I596_630	Threonine aldolase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.938
I596_26	kbl	I596_26	I596_2038	Threonine aldolase.	2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.	0.912
I596_3075	I596_3785	I596_3075	I596_3785	Class I and II aminotransferase.	Cystathionine beta-lyase/cystathionine gamma-synthase.	0.916
I596_3075	I596_3793	I596_3075	I596_3793	Class I and II aminotransferase.	Aminotransferase AlaT.	0.900
I596_3075	hisC	I596_3075	I596_1704	Class I and II aminotransferase.	Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.934
I596_3075	hisC-2	I596_3075	I596_3476	Class I and II aminotransferase.	Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.909
I596_3785	I596_3075	I596_3785	I596_3075	Cystathionine beta-lyase/cystathionine gamma-synthase.	Class I and II aminotransferase.	0.916
I596_3785	I596_736	I596_3785	I596_736	Cystathionine beta-lyase/cystathionine gamma-synthase.	Cystathionine gamma-synthase.	0.906
I596_3793	I596_1563	I596_3793	I596_1563	Aminotransferase AlaT.	Alanine-glyoxylate aminotransferase apoenzyme.	0.926
I596_3793	I596_3075	I596_3793	I596_3075	Aminotransferase AlaT.	Class I and II aminotransferase.	0.900