STRINGSTRING
cdhC cdhC AIJ04853.1 AIJ04853.1 AIJ04854.1 AIJ04854.1 cdhA cdhA cdhC-2 cdhC-2 AIJ04862.1 AIJ04862.1 hemA hemA AIJ04866.1 AIJ04866.1 apgM apgM pgi pgi pfkC pfkC rpiA rpiA sat sat cysC cysC AIJ04960.1 AIJ04960.1 AIJ04961.1 AIJ04961.1 AIJ04976.1 AIJ04976.1 mer mer tpiA tpiA AIJ05006.1 AIJ05006.1 AIJ05007.1 AIJ05007.1 AIJ05008.1 AIJ05008.1 AIJ05009.1 AIJ05009.1 AIJ05010.1 AIJ05010.1 AIJ05011.1 AIJ05011.1 AIJ05017.1 AIJ05017.1 AIJ05019.1 AIJ05019.1 AIJ05020.1 AIJ05020.1 AIJ05021.1 AIJ05021.1 AIJ05023.1 AIJ05023.1 AIJ05043.1 AIJ05043.1 AIJ05048.1 AIJ05048.1 AIJ05049.1 AIJ05049.1 AIJ05085.1 AIJ05085.1 AIJ05098.1 AIJ05098.1 AIJ05104.1 AIJ05104.1 AIJ05106.1 AIJ05106.1 AIJ05127.1 AIJ05127.1 AIJ05131.1 AIJ05131.1 AIJ05132.1 AIJ05132.1 AIJ05140.1 AIJ05140.1 AIJ05182.1 AIJ05182.1 gltX gltX prs prs AIJ05271.1 AIJ05271.1 AIJ05296.1 AIJ05296.1 hacB hacB cofD cofD AIJ05327.1 AIJ05327.1 sucD sucD AIJ05333.1 AIJ05333.1 AIJ05345.1 AIJ05345.1 AIJ05353.1 AIJ05353.1 AIJ05354.1 AIJ05354.1 AIJ05355.1 AIJ05355.1 AIJ05365.1 AIJ05365.1 mch mch AIJ05394.1 AIJ05394.1 cofH cofH fae-hps fae-hps AIJ05450.1 AIJ05450.1 AIJ05456.1 AIJ05456.1 rbcL rbcL AIJ05460.1 AIJ05460.1 AIJ05461.1 AIJ05461.1 AIJ05497.1 AIJ05497.1 AIJ05500.1 AIJ05500.1 AIJ05501.1 AIJ05501.1 AIJ05503.1 AIJ05503.1 AIJ05509.1 AIJ05509.1 AIJ05520.1 AIJ05520.1 AIJ05522.1 AIJ05522.1 AIJ05523.1 AIJ05523.1 AIJ05524.1 AIJ05524.1 AIJ05525.1 AIJ05525.1 AIJ05526.1 AIJ05526.1 gap gap AIJ05554.1 AIJ05554.1 dapF dapF AIJ05596.1 AIJ05596.1 cdhD cdhD cdhE cdhE AIJ05608.1 AIJ05608.1 AIJ05610.1 AIJ05610.1 glyA glyA AIJ05615.1 AIJ05615.1 ubiX ubiX hemC hemC lysA lysA thrB thrB AIJ05648.1 AIJ05648.1 AIJ05661.1 AIJ05661.1 hemL hemL AIJ05687.1 AIJ05687.1 pgk pgk AIJ05709.1 AIJ05709.1 AIJ05710.1 AIJ05710.1 fbp fbp ftr ftr mtd mtd AIJ05770.1 AIJ05770.1 leuC leuC AIJ05801.1 AIJ05801.1 AIJ05806.1 AIJ05806.1 cofC cofC AIJ05871.1 AIJ05871.1 AIJ05879.1 AIJ05879.1 AIJ05880.1 AIJ05880.1 mtrH mtrH mtrG mtrG mtrA mtrA mtrB mtrB mtrC mtrC mtrB-2 mtrB-2 mtrC-2 mtrC-2 mtrD mtrD mtrE mtrE AIJ05899.1 AIJ05899.1 AIJ05900.1 AIJ05900.1 AIJ05901.1 AIJ05901.1 AIJ05902.1 AIJ05902.1 AIJ05903.1 AIJ05903.1 hmd hmd cofE cofE AIJ05994.1 AIJ05994.1 AIJ05995.1 AIJ05995.1 AIJ05996.1 AIJ05996.1 AIJ05997.1 AIJ05997.1 argD argD AIJ06059.1 AIJ06059.1 AIJ06060.1 AIJ06060.1 AIJ06061.1 AIJ06061.1 AIJ06082.1 AIJ06082.1 cbiX cbiX AIJ06105.1 AIJ06105.1 tal tal aroA aroA dapB dapB cofG cofG AIJ06212.1 AIJ06212.1 AIJ06248.1 AIJ06248.1 AIJ06259.1 AIJ06259.1 AIJ06261.1 AIJ06261.1 AIJ06262.1 AIJ06262.1 AIJ06263.1 AIJ06263.1 AIJ06267.1 AIJ06267.1 AIJ06321.1 AIJ06321.1 AIJ06376.1 AIJ06376.1 AIJ06377.1 AIJ06377.1 AIJ06378.1 AIJ06378.1 AIJ06379.1 AIJ06379.1 AIJ06380.1 AIJ06380.1 dapA dapA eno eno sucC sucC asd asd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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cdhCCO dehydrogenase/acetyl-CoA synthase beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. (467 aa)
AIJ04853.1CO dehydrogenase, iron-sulfur subunit; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (151 aa)
AIJ04854.1CO dehydrogenase/acetyl-CoA synthase epsilon subunit; COG1880. (146 aa)
cdhACO dehydrogenase/acetyl-CoA synthase alpha subunit; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. (773 aa)
cdhC-2CO dehydrogenase/acetyl-CoA synthase beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family. (738 aa)
AIJ04862.12-ketoglutarate ferredoxin oxidoreductase subunit delta; COG1146. (69 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (392 aa)
AIJ04866.1Siroheme synthase; COG1648. (208 aa)
apgMPhosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (410 aa)
pgiGlucose-6-phosphate isomerase; COG0166; Belongs to the GPI family. (408 aa)
pfkCADP-specific phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (460 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (205 aa)
satSulfate adenylyltransferase; COG2046; Belongs to the sulfate adenylyltransferase family. (382 aa)
cysCAdenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. (174 aa)
AIJ04960.14-oxalocrotonate tautomerase; COG1942. (63 aa)
AIJ04961.1Formylmethanofuran dehydrogenase subunit E; COG2191. (199 aa)
AIJ04976.1Beta-ketoacyl synthase; COG0183. (392 aa)
mer5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. (331 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (219 aa)
AIJ05006.1Pyruvate ferredoxin oxidoreductase gamma subunit; COG1014. (131 aa)
AIJ05007.1Pyruvate ferredoxin oxidoreductase delta subunit; COG1144. (86 aa)
AIJ05008.1Pyruvate ferredoxin oxidoreductase alpha subunit; COG0674. (386 aa)
AIJ05009.1Pyruvate ferredoxin oxidoreductase beta subunit; COG1013. (295 aa)
AIJ05010.1Formate hydrogenlyase, subunit 2; COG1142. (164 aa)
AIJ05011.14Fe-4S ferredoxin iron-sulfur binding domain protein; COG1142. (141 aa)
AIJ05017.1Mur ligase middle domain protein; COG0770. (400 aa)
AIJ05019.1Thiamine pyrophosphate TPP-binding domain-containing protein; COG0028. (188 aa)
AIJ05020.1Sulfopyruvate decarboxylase subunit ComD; COG4032. (168 aa)
AIJ05021.1Phosphosulfolactate synthase; COG1809. (251 aa)
AIJ05023.1Coenzyme F420-reducing hydrogenase maturation factor subunit delta; COG0680. (157 aa)
AIJ05043.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (765 aa)
AIJ05048.1Thiamine pyrophosphate protein domain protein TPP-binding protein; COG1013. (243 aa)
AIJ05049.1Pyruvate ferredoxin oxidoreductase gamma subunit; COG1014. (180 aa)
AIJ05085.1Pyruvate ferredoxin oxidoreductase alpha subunit; COG0674. (366 aa)
AIJ05098.1Formate dehydrogenase subunit alpha; COG0243. (497 aa)
AIJ05104.1Coenzyme F420-reducing hydrogenase, beta subunit; COG1035. (355 aa)
AIJ05106.1Glutamine synthetase; COG0174; Belongs to the glutamine synthetase family. (448 aa)
AIJ05127.1Phosphonopyruvate decarboxylase-related protein; COG3635. (384 aa)
AIJ05131.1Molybdopterin oxidoreductase; COG0243. (377 aa)
AIJ05132.1Coenzyme F420-reducing hydrogenase, beta subunit; COG1035. (379 aa)
AIJ05140.1Aldolase; COG1830. (306 aa)
AIJ05182.1Fumarate hydratase; COG1951. (286 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (553 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (284 aa)
AIJ05271.1Homoserine dehydrogenase; COG0460. (336 aa)
AIJ05296.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (405 aa)
hacB3-isopropylmalate dehydratase small subunit; Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B; Belongs to the LeuD f [...] (164 aa)
cofDLPPG domain protein containing protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (307 aa)
AIJ05327.16-phospho 3-hexuloisomerase; COG0794. (177 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (288 aa)
AIJ05333.1Methyl coenzyme M reductase system, component A2; COG1123. (534 aa)
AIJ05345.1Succinate dehydrogenase/fumarate reductase iron-sulfur subunit; COG0247. (489 aa)
AIJ05353.1Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (552 aa)
AIJ05354.1Methyl-coenzyme M reductase, gamma subunit; COG4057. (266 aa)
AIJ05355.1Methyl-coenzyme M reductase, beta subunit; COG4054. (447 aa)
AIJ05365.1Hypothetical protein; COG0175. (474 aa)
mchMethenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family. (323 aa)
AIJ05394.1Vanadium nitrogenase-associated protein N; COG2710. (351 aa)
cofH7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (359 aa)
fae-hpsBifunctional formaldehyde-activating enzyme/3-hexulo se-6-phosphate synthase; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. (379 aa)
AIJ05450.1Class II aldolase/adducin family protein; COG0235. (181 aa)
AIJ05456.1Glyceraldehyde-3-phosphate dehydrogenase; COG1012. (463 aa)
rbcLRibulose 1,5-bisphosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (425 aa)
AIJ05460.1Pyruvate carboxylase subunit B; COG5016. (567 aa)
AIJ05461.1acetyl-CoA carboxylase, biotin carboxylase; COG0439. (501 aa)
AIJ05497.1Formylmethanofuran dehydrogenase subunit B; COG1029. (279 aa)
AIJ05500.1Coenzyme F420-reducing hydrogenase, alpha subunit; COG3259. (418 aa)
AIJ05501.1Coenzyme F420-reducing hydrogenase, gamma subunit; COG1941. (279 aa)
AIJ05503.1CoB/CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (460 aa)
AIJ05509.1Aldehyde ferredoxin oxidoreductase; COG2414. (622 aa)
AIJ05520.1Formylmethanofuran dehydrogenase subunit C; COG2218. (273 aa)
AIJ05522.1Formylmethanofuran dehydrogenase subunit A; COG1229. (546 aa)
AIJ05523.1Formylmethanofuran dehydrogenase subunit D; COG1153. (133 aa)
AIJ05524.1Formylmethanofuran dehydrogenase subunit G; COG1145. (82 aa)
AIJ05525.14Fe-4S ferredoxin iron-sulfur binding domain protein; COG1145. (355 aa)
AIJ05526.14Fe-4S ferredoxin; COG1146. (148 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase, type II; COG0057. (343 aa)
AIJ05554.1Hypothetical protein; COG2045. (224 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. (295 aa)
AIJ05596.1Methyl-coenzyme M reductase operon protein D; COG4055. (160 aa)
cdhDCO dehydrogenase/acetyl-CoA synthase delta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family. (396 aa)
cdhECO dehydrogenase/acetyl-CoA synthase gamma subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). (490 aa)
AIJ05608.1Phosphoserine phosphatase SerB; COG0560. (211 aa)
AIJ05610.1Isocitrate dehydrogenase; COG0473. (348 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro- aldol mechanism; Belongs to the SHMT family. (429 aa)
AIJ05615.1Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family. (443 aa)
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (183 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (292 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (435 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (296 aa)
AIJ05648.1Aspartate kinase; COG0527; Belongs to the aspartokinase family. (431 aa)
AIJ05661.1Acetyl coenzyme A synthetase (ADP forming), alpha domain protein; COG1042. (699 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; COG0001. (426 aa)
AIJ05687.1Fe-S type, hydrlyase, tartrate/fumarate subfamily, beta subunit; COG1838. (197 aa)
pgkPhosphoglycerate kinase; COG0126; Belongs to the phosphoglycerate kinase family. (415 aa)
AIJ05709.1Delta-aminolevulinic acid dehydratase; COG0113; Belongs to the ALAD family. (322 aa)
AIJ05710.1Dimethylmenaquinone methyltransferase; COG0684. (196 aa)
fbpHypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (395 aa)
ftrFormylmethanofuran/tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. (301 aa)
mtdF420-dependent methylene tetrahydro methanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (235 aa)
AIJ05770.1D-3-phosphoglycerate dehydrogenase; COG0111; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (524 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (391 aa)
AIJ05801.1alpha-L-glutamate ligase, RimK family; COG0189. (288 aa)
AIJ05806.1Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (239 aa)
cofCHypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (219 aa)
AIJ05871.1Nitrogenase iron protein; COG1348; Belongs to the NifH/BchL/ChlL family. (213 aa)
AIJ05879.1CoB/CoM heterodisulfide reductase subunit C; COG1150. (186 aa)
AIJ05880.1CoB/CoM heterodisulfide reductase subunit B; COG2048. (295 aa)
mtrHTetrahydromethanopterin S-methyltransferase, subunit H; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA. (319 aa)
mtrGTetrahydromethanopterin S-methyltransferase, subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (78 aa)
mtrATetrahydromethanopterin S-methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (253 aa)
mtrBTetrahydromethanopterin S-methyltransferase, subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (107 aa)
mtrCTetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (183 aa)
mtrB-2Tetrahydromethanopterin S-methyltransferase, subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (109 aa)
mtrC-2Tetrahydromethanopterin S-methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (265 aa)
mtrDTetrahydromethanopterin S-methyltransferase, subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (229 aa)
mtrETetrahydromethanopterin S-methyltransferase, subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (300 aa)
AIJ05899.1Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (553 aa)
AIJ05900.1Methyl-coenzyme M reductase, gamma subunit; COG4057. (260 aa)
AIJ05901.1Methyl-coenzyme M reductase operon protein C; COG4056. (158 aa)
AIJ05902.1Methyl-coenzyme M reductase operon protein D; COG4055. (163 aa)
AIJ05903.1Methyl-coenzyme M reductase, beta subunit; COG4054. (444 aa)
hmdH(2)-dependent methylene tetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (321 aa)
cofEF420-dependent oxidoreductase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. (249 aa)
AIJ05994.1Coenzyme F420-reducing hydrogenase, beta subunit; COG1035. (261 aa)
AIJ05995.1Coenzyme F420-reducing hydrogenase, gamma subunit; COG1941. (214 aa)
AIJ05996.1Coenzyme F420-reducing hydrogenase, alpha subunit; COG3259. (298 aa)
AIJ05997.1CO dehydrogenase, catalytic subunit; COG1151. (624 aa)
argDAcetylornithine and succinylornithine aminotransferase; COG4992; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (398 aa)
AIJ06059.1Transketolase, N-terminal subunit; COG3959. (275 aa)
AIJ06060.1Pentose-5-phosphate-3-epimerase; COG0036; Belongs to the ribulose-phosphate 3-epimerase family. (222 aa)
AIJ06061.1Transketolase, C-terminal subunit; COG3958. (316 aa)
AIJ06082.1Glutamate synthase alpha subunit domain protein; COG2218. (318 aa)
cbiXSirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. (148 aa)
AIJ06105.1uroporphyrin-III C-methyltransferase; COG0007. (242 aa)
talPutative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
aroAFructose-bisphosphate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (273 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (274 aa)
cofGFO synthase subunit; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (358 aa)
AIJ06212.1Diaminopimelate aminotransferas; COG0624. (376 aa)
AIJ06248.1Malate dehydrogenase; COG0039; Belongs to the LDH/MDH superfamily. (313 aa)
AIJ06259.1Formylmethanofuran dehydrogenase subunit B; COG1029. (317 aa)
AIJ06261.1Formylmethanofuran dehydrogenase subunit C; COG2218. (412 aa)
AIJ06262.1Formylmethanofuran dehydrogenase subunit A; COG1229. (561 aa)
AIJ06263.1Formylmethanofuran dehydrogenase subunit E; COG2191. (190 aa)
AIJ06267.1Trans-homoaconitate synthase; COG0119; Belongs to the alpha-IPM synthase/homocitrate synthase family. (398 aa)
AIJ06321.1ABC transporter; COG1123. (555 aa)
AIJ06376.1Coenzyme F420-reducing hydrogenase, alpha subunit; COG3259. (385 aa)
AIJ06377.1Coenzyme F420-reducing hydrogenase maturation factor subunit delta, type 2; COG0680. (155 aa)
AIJ06378.1Coenzyme F420-reducing hydrogenase, gamma subunit; COG1941. (227 aa)
AIJ06379.1Coenzyme F420-reducing hydrogenase, beta subunit; COG1035. (282 aa)
AIJ06380.1Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; COG1053. (540 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (289 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (356 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (365 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (348 aa)
Your Current Organism:
Methanocaldococcus bathoardescens
NCBI taxonomy Id: 1301915
Other names: DSM 27223, KACC 18232, M. bathoardescens, Methanocaldococcus bathoardescens Stewart et al. 2015, Methanocaldococcus sp. JH146, strain JH146
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