STRINGSTRING
rr02 rr02 ywnA ywnA KXU16759.1 KXU16759.1 KXU16761.1 KXU16761.1 KXU16756.1 KXU16756.1 KXU16746.1 KXU16746.1 KXU16741.1 KXU16741.1 birA birA sun sun rsfS rsfS yqeH yqeH prfC prfC efp efp nusB nusB KXU16708.1 KXU16708.1 liaR liaR KXU16666.1 KXU16666.1 RitR RitR KXU16662.1 KXU16662.1 KXU16610.1 KXU16610.1 fusA fusA KXU16595.1 KXU16595.1 KXU16596.1 KXU16596.1 KXU16586.1 KXU16586.1 KXU16590.1 KXU16590.1 yeeN yeeN KXU16573.1 KXU16573.1 KXU16554.1 KXU16554.1 infA infA spxA_1 spxA_1 KXU16497.1 KXU16497.1 argR argR KXU16479.1 KXU16479.1 KXU16480.1 KXU16480.1 KXU16471.1 KXU16471.1 KXU16436.1 KXU16436.1 KXU16438.1 KXU16438.1 adcR adcR ctsR ctsR KXU16382.1 KXU16382.1 raiA raiA KXU16357.1 KXU16357.1 tsf tsf KXU16351.1 KXU16351.1 lacR lacR nrdH nrdH KXU16319.1 KXU16319.1 KXU16320.1 KXU16320.1 lpdA lpdA KXU16250.1 KXU16250.1 walK_2 walK_2 rex rex prfA prfA KXU16207.1 KXU16207.1 KXU16154.1 KXU16154.1 graR graR KXU16150.1 KXU16150.1 ywnA-2 ywnA-2 KXU16123.1 KXU16123.1 scaR scaR codY codY VncR VncR KXU16091.1 KXU16091.1 KXU16093.1 KXU16093.1 KXU16080.1 KXU16080.1 KXU16055.1 KXU16055.1 KXU16031.1 KXU16031.1 KXU16027.1 KXU16027.1 KXU16021.1 KXU16021.1 KXU15990.1 KXU15990.1 trxA trxA KXU15994.1 KXU15994.1 ytrA ytrA nrdR nrdR KXU15971.1 KXU15971.1 glnR glnR KXU15975.1 KXU15975.1 hrcA hrcA KXU15948.1 KXU15948.1 KXU15936.1 KXU15936.1 KXU15937.1 KXU15937.1 KXU15911.1 KXU15911.1 hcaR hcaR KXU15830.1 KXU15830.1 nox nox KXU15802.1 KXU15802.1 mgsR mgsR KXU15772.1 KXU15772.1 ydjZ ydjZ KXU15778.1 KXU15778.1 KXU15779.1 KXU15779.1 ykuL ykuL KXU15683.1 KXU15683.1 KXU15639.1 KXU15639.1 KXU15625.1 KXU15625.1 mutS2 mutS2 KXU15577.1 KXU15577.1 KXU15541.1 KXU15541.1 lepA lepA argR_3 argR_3 KXU15438.1 KXU15438.1 greA greA prfB prfB LicA LicA ethR ethR KXU15383.1 KXU15383.1 KXU15385.1 KXU15385.1 rplA rplA dacA dacA tuf tuf KXU15303.1 KXU15303.1 argR_3-2 argR_3-2 sigA sigA KXU15183.1 KXU15183.1 KXU15188.1 KXU15188.1 gor gor KXU15056.1 KXU15056.1 hprK hprK spxA_3 spxA_3 phoU phoU KXU14986.1 KXU14986.1 KXU14960.1 KXU14960.1 KXU14953.1 KXU14953.1 mecA mecA cysB cysB KXU14571.1 KXU14571.1 KXU14550.1 KXU14550.1 frlR frlR KXU14372.1 KXU14372.1 KXU14385.1 KXU14385.1 KXU14386.1 KXU14386.1 FruR FruR purR purR KXU14169.1 KXU14169.1 KXU14114.1 KXU14114.1 malR malR KXU13953.1 KXU13953.1 KXU13947.1 KXU13947.1 KXU13879.1 KXU13879.1 KXU13727.1 KXU13727.1 KXU13651.1 KXU13651.1 KXU13652.1 KXU13652.1 recX recX rpoE rpoE mfd mfd dnaA dnaA KXU13522.1 KXU13522.1 KXU13509.1 KXU13509.1 KXU13510.1 KXU13510.1 KXU13475.1 KXU13475.1 KXU13455.1 KXU13455.1 arlR_2 arlR_2 infB infB nusA nusA KXU13306.1 KXU13306.1 ccpA ccpA KXU13242.1 KXU13242.1 comC comC agrA_2 agrA_2 infC infC KXU13153.1 KXU13153.1 KXU13131.1 KXU13131.1 yumC yumC KXU12360.1 KXU12360.1 KXU12295.1 KXU12295.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rr02Two-component response regulator SA14-24. (235 aa)
ywnAtRNA-Lys-CTT. (143 aa)
KXU16759.1Galactose operon repressor, GalR-LacI transcriptional regulator family. (334 aa)
KXU16761.1Transcriptional regulator, MerR family. (118 aa)
KXU16756.1Transcriptional regulator, TetR family. (182 aa)
KXU16746.1Transcriptional regulator SczA, TetR family. (184 aa)
KXU16741.1Transcriptional regulator, MarR family. (147 aa)
birABiotin-protein ligase / Biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (311 aa)
sunRibosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (197 aa)
rsfSIojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (117 aa)
yqeHGTP-binding protein YqeH; Required for biogenesis of 30S ribosome subunit. (368 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (514 aa)
efpTranslation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (186 aa)
nusBTranscription termination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (120 aa)
KXU16708.1Transcriptional regulator of fatty acid biosynthesis FabT. (144 aa)
liaRTwo component transcriptional regulator VraR. (210 aa)
KXU16666.1Sensor histidine kinase VraS. (332 aa)
RitRResponse regulator CsrR. (152 aa)
KXU16662.1Response regulator CsrR. (58 aa)
KXU16610.1Transcriptional regulator, TetR family. (210 aa)
fusATranslation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (378 aa)
KXU16595.1Two-component response regulator. (199 aa)
KXU16596.1Sensor histidine kinase. (307 aa)
KXU16586.1Response regulator of the LytR/AlgR family. (148 aa)
KXU16590.1Transcriptional regulator, MarR family. (153 aa)
yeeNYeeN-like protein. (254 aa)
KXU16573.1M protein trans-acting positive regulator (Mga). (494 aa)
KXU16554.1Transcriptional regulator, AraC family. (292 aa)
infATranslation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
spxA_1Transcriptional regulator SpxA2; Belongs to the ArsC family. (132 aa)
KXU16497.1Hypothetical protein. (146 aa)
argRPutative arginine repressor ArgR; Regulates arginine biosynthesis genes. (148 aa)
KXU16479.1DNA-binding response regulator, AraC family. (428 aa)
KXU16480.1Two-component sensor histidine kinase. (548 aa)
KXU16471.1Positive transcriptional regulator, MutR family. (287 aa)
KXU16436.1Transcriptional regulator, PadR family. (108 aa)
KXU16438.1Putative membrane associated protein. (312 aa)
adcRTranscriptional repressor AdcR for Zn(2+)-responsive expression. (146 aa)
ctsRTranscriptional regulator CtsR; Belongs to the CtsR family. (152 aa)
KXU16382.1Hypothetical protein. (88 aa)
raiARibosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (180 aa)
KXU16357.1Protein co-occurring with transport systems, COG1739. (211 aa)
tsfTranslation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (346 aa)
KXU16351.1Beta-glucoside bgl operon antiterminator, BglG family. (277 aa)
lacRLactose phosphotransferase system repressor. (254 aa)
nrdHGlutaredoxin-like protein NrdH; Required for reduction of Ribonucleotide reductase class Ib. (72 aa)
KXU16319.1Hypothetical protein. (232 aa)
KXU16320.1Putative histidine kinase. (291 aa)
lpdADihydrolipoamide dehydrogenase of acetoin dehydrogenase. (567 aa)
KXU16250.1Two-component sensor kinase; Overlaps another CDS with the same product name, SA14-24-like protein. (78 aa)
walK_2Two-component sensor kinase; Overlaps another CDS with the same product name, SA14-24-like protein. (359 aa)
rexRedox-sensitive transcriptional regulator (AT-rich DNA-binding protein); Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (213 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (359 aa)
KXU16207.1Phage protein. (135 aa)
KXU16154.1Transcriptional regulator, TetR family. (187 aa)
graRTwo-component response regulator. (225 aa)
KXU16150.1Two-component system histidine kinase. (300 aa)
ywnA-2Rrf2 family transcriptional regulator, group III. (145 aa)
KXU16123.1Malolactic regulator. (294 aa)
scaRMn-dependent transcriptional regulator MntR. (223 aa)
codYGTP-sensing transcriptional pleiotropic repressor codY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. (262 aa)
VncRTwo-component response regulator VncR. (218 aa)
KXU16091.1Sensor histidine kinase VncS. (442 aa)
KXU16093.1Transcriptional regulator, MerR family. (111 aa)
KXU16080.1Hypothetical protein; Contains S4-like RNA binding domain. (263 aa)
KXU16055.1Sialic acid utilization regulator, RpiR family. (283 aa)
KXU16031.1Transposase; ISSpo3. (305 aa)
KXU16027.1Putative Dihydrolipoamide dehydrogenase / Mercuric ion reductase / PF00070 family, FAD-dependent NAD(P)-disulfide oxidoreductase. (438 aa)
KXU16021.1Putative ATP-binding protein; Displays ATPase and GTPase activities. (296 aa)
KXU15990.1Transcriptional regulator, HxlR family. (115 aa)
trxAThioredoxin; Belongs to the thioredoxin family. (107 aa)
KXU15994.1Transcriptional regulator, MarR family. (92 aa)
ytrATranscriptional regulator, GntR family. (121 aa)
nrdRRibonucleotide reductase transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (157 aa)
KXU15971.1Hypothetical protein. (156 aa)
glnRTranscriptional regulator, repressor of the glutamine synthetase, MerR family. (118 aa)
KXU15975.1Transcriptional regulator, PadR family. (106 aa)
hrcAHeat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (344 aa)
KXU15948.1thiJ/pfpI family protein. (210 aa)
KXU15936.1Response regulator of the competence regulon ComE. (245 aa)
KXU15937.1BlpS protein. (112 aa)
KXU15911.1Transcriptional regulator, DeoR family. (199 aa)
hcaRMethionine biosynthesis and transport regulator MtaR, LysR family; Belongs to the LysR transcriptional regulatory family. (308 aa)
KXU15830.1Negative transcriptional regulator-copper transport operon. (131 aa)
noxNADH oxidase H2O-forming. (129 aa)
KXU15802.1Hypothetical protein. (148 aa)
mgsRArsenate reductase; Belongs to the ArsC family. (118 aa)
KXU15772.1Transcriptional regulator, MarR family. (148 aa)
ydjZImmunoreactive protein Se23.5. (205 aa)
KXU15778.1Sucrose operon repressor ScrR, LacI family; Overlaps another CDS with the same product name. (292 aa)
KXU15779.1Sucrose operon repressor ScrR, LacI family; Overlaps another CDS with the same product name. (38 aa)
ykuLCBS domain containing protein. (153 aa)
KXU15683.1Trehalose operon transcriptional repressor. (240 aa)
KXU15639.1Transcriptional regulator, MarR family. (141 aa)
KXU15625.1Transcriptional regulator, PBSX family. (64 aa)
mutS2Recombination inhibitory protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (778 aa)
KXU15577.1Membrane protein; Belongs to the BI1 family. (227 aa)
KXU15541.1Hypothetical protein. (89 aa)
lepATranslation elongation factor LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (607 aa)
argR_3Putative arginine repressor ArgR; Regulates arginine biosynthesis genes. (115 aa)
KXU15438.1Transcriptional repressor. (69 aa)
greATranscription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (160 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (127 aa)
LicACholinephosphate cytidylyltransferase / Choline kinase. (592 aa)
ethRTranscriptional regulator, TetR family. (185 aa)
KXU15383.1Transcriptional regulator, TetR family. (182 aa)
KXU15385.1Regulator of the multidrug efflux pump pmrA. (246 aa)
rplALSU ribosomal protein L1p (L10Ae); Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (229 aa)
dacAHypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (237 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (398 aa)
KXU15303.1Cytosolic protein containing multiple CBS domain. (425 aa)
argR_3-2Arginine pathway regulatory protein ArgR, repressor of arg regulon; Regulates arginine biosynthesis genes. (156 aa)
sigARNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (369 aa)
KXU15183.1Transcriptional regulator in cluster with beta-lactamase, GntR family. (232 aa)
KXU15188.1Hypothetical protein. (148 aa)
gorGlutathione reductase. (448 aa)
KXU15056.1Abortive infection protein AbiGI. (197 aa)
hprKHPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...] (311 aa)
spxA_3Transcriptional regulator SpxA1; Belongs to the ArsC family. (101 aa)
phoUPhosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake. (217 aa)
KXU14986.1Putative transcriptional regulator of pyridoxine metabolism. (423 aa)
KXU14960.1Sugar-binding transcriptional regulator, LacI family. (310 aa)
KXU14953.1Transcriptional regulator, AraC family. (273 aa)
mecANegative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. (246 aa)
cysBCysteine and methionine metabolism regulator CmbR, LysR family; Belongs to the LysR transcriptional regulatory family. (302 aa)
KXU14571.1Programmed cell death antitoxin MazE. (43 aa)
KXU14550.1Nitrogen assimilation transcriptional activator NtcB. (296 aa)
frlRTranscriptional regulator, GntR family. (202 aa)
KXU14372.1Putative transcriptional regulator (DeoR family). (247 aa)
KXU14385.1Bacterial seryl-tRNA synthetase related. (71 aa)
KXU14386.1Putative transcriptional regulator, TetR family. (190 aa)
FruRTranscriptional repressor of the fructose operon, DeoR family. (219 aa)
purRPurR: transcription regulator associated with purine metabolism. (267 aa)
KXU14169.1Hypothetical protein. (228 aa)
KXU14114.1Ascorbate-specific PTS system, EIIA component. (161 aa)
malRMaltose operon transcriptional repressor MalR, LacI family. (328 aa)
KXU13953.1Two-component response regulator yesN, associated with MetSO reductase. (245 aa)
KXU13947.1Two-component sensor kinase yesM, associated with MetSO reductase. (494 aa)
KXU13879.1Hypothetical protein. (190 aa)
KXU13727.1Hypothetical protein. (287 aa)
KXU13651.1Hypothetical protein. (62 aa)
KXU13652.1Phage repressor. (249 aa)
recXRegulatory protein recX; Modulates RecA activity; Belongs to the RecX family. (258 aa)
rpoEDNA-directed RNA polymerase delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (196 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (861 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (134 aa)
KXU13522.1Chromosome (plasmid) partitioning protein ParB / Stage 0 sporulation protein J; Belongs to the ParB family. (252 aa)
KXU13509.1Hypothetical protein. (190 aa)
KXU13510.1Hypothetical protein. (291 aa)
KXU13475.1Hypothetical protein. (66 aa)
KXU13455.1Two component system sensor histidine kinase CiaH. (445 aa)
arlR_2Two component system response regulator CiaR. (224 aa)
infBTranslation initiation factor 2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (155 aa)
nusATranscription termination protein NusA; Participates in both transcription termination and antitermination. (378 aa)
KXU13306.1Putative transcriptional regulator, XRE family. (109 aa)
ccpACatabolite control protein A. (336 aa)
KXU13242.1Hypothetical protein. (150 aa)
comCCompetence-stimulating peptide / CSP; Acts as a pheromone, induces cells to develop competence for genetic transformation; Belongs to the ComC family. (41 aa)
agrA_2Response regulator of the competence regulon ComE. (250 aa)
infCTranslation initiation factor 3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (185 aa)
KXU13153.1Sensor-receptor histidine kinase NisK. (97 aa)
KXU13131.1Transcriptional regulator, TetR family. (180 aa)
yumCThioredoxin reductase. (268 aa)
KXU12360.1Hypothetical protein. (190 aa)
KXU12295.1Phage protein. (68 aa)
Your Current Organism:
Streptococcus oralis
NCBI taxonomy Id: 1303
Other names: ATCC 35037, CCUG 13229, CCUG 24891, CIP 102922, DSM 20627, JCM 12997, LMG 14532, LMG:14532, NCTC 11427, S. oralis, strain LVG 1, strain PB 182, strain SK23
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