STRINGSTRING
cofG cofG AFZ48884.1 AFZ48884.1 AFZ48962.1 AFZ48962.1 AFZ48985.1 AFZ48985.1 AFZ49011.1 AFZ49011.1 AFZ49029.1 AFZ49029.1 AFZ49116.1 AFZ49116.1 AFZ49146.1 AFZ49146.1 AFZ49172.1 AFZ49172.1 AFZ49286.1 AFZ49286.1 AFZ49298.1 AFZ49298.1 AFZ49405.1 AFZ49405.1 AFZ49432.1 AFZ49432.1 AFZ49455.1 AFZ49455.1 AFZ49456.1 AFZ49456.1 AFZ49458.1 AFZ49458.1 cpdA cpdA AFZ49571.1 AFZ49571.1 AFZ49597.1 AFZ49597.1 AFZ49598.1 AFZ49598.1 AFZ49672.1 AFZ49672.1 AFZ49827.1 AFZ49827.1 AFZ49882.1 AFZ49882.1 AFZ49883.1 AFZ49883.1 AFZ49884.1 AFZ49884.1 AFZ49885.1 AFZ49885.1 AFZ49964.1 AFZ49964.1 AFZ50020.1 AFZ50020.1 thiE thiE AFZ50022.1 AFZ50022.1 thiG thiG AFZ50151.1 AFZ50151.1 AFZ50179.1 AFZ50179.1 AFZ50180.1 AFZ50180.1 AFZ50181.1 AFZ50181.1 AFZ50182.1 AFZ50182.1 AFZ50183.1 AFZ50183.1 AFZ50184.1 AFZ50184.1 AFZ50188.1 AFZ50188.1 AFZ50249.1 AFZ50249.1 AFZ50250.1 AFZ50250.1 AFZ50251.1 AFZ50251.1 AFZ50256.1 AFZ50256.1 AFZ50356.1 AFZ50356.1 AFZ50366.1 AFZ50366.1 AFZ50369.1 AFZ50369.1 AFZ50370.1 AFZ50370.1 AFZ50393.1 AFZ50393.1 AFZ50504.1 AFZ50504.1 AFZ50562.1 AFZ50562.1 AFZ50626.1 AFZ50626.1 AFZ50627.1 AFZ50627.1 AFZ50628.1 AFZ50628.1 AFZ50681.1 AFZ50681.1 AFZ50707.1 AFZ50707.1 AFZ50755.1 AFZ50755.1 AFZ50780.1 AFZ50780.1 AFZ50906.1 AFZ50906.1 AFZ50916.1 AFZ50916.1 AFZ50938.1 AFZ50938.1 AFZ50971.1 AFZ50971.1 AFZ50972.1 AFZ50972.1 AFZ51003.1 AFZ51003.1 AFZ51004.1 AFZ51004.1 AFZ51018.1 AFZ51018.1 AFZ51029.1 AFZ51029.1 sfsA sfsA AFZ51084.1 AFZ51084.1 AFZ51102.1 AFZ51102.1 AFZ51136.1 AFZ51136.1 thiC thiC AFZ51269.1 AFZ51269.1 AFZ51270.1 AFZ51270.1 cofH cofH AFZ51423.1 AFZ51423.1 AFZ51424.1 AFZ51424.1 AFZ51425.1 AFZ51425.1 AFZ51525.1 AFZ51525.1 AFZ51561.1 AFZ51561.1 AFZ51580.1 AFZ51580.1 AFZ51599.1 AFZ51599.1 AFZ51600.1 AFZ51600.1 AFZ51635.1 AFZ51635.1 AFZ51636.1 AFZ51636.1 AFZ51637.1 AFZ51637.1 AFZ51638.1 AFZ51638.1 AFZ51683.1 AFZ51683.1 AFZ51684.1 AFZ51684.1 AFZ51685.1 AFZ51685.1 AFZ51686.1 AFZ51686.1 sasA sasA AFZ51758.1 AFZ51758.1 AFZ51963.1 AFZ51963.1 AFZ51971.1 AFZ51971.1 AFZ51972.1 AFZ51972.1 AFZ52117.1 AFZ52117.1 AFZ52118.1 AFZ52118.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cofG7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. (315 aa)
AFZ48884.1PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (733 aa)
AFZ48962.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (241 aa)
AFZ48985.1PFAM: Response regulator receiver domain. (131 aa)
AFZ49011.1PFAM: EAL domain; GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. (563 aa)
AFZ49029.1Chemotaxis protein histidine kinase-like protein; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Signal transducing histidine kinase, homodimeric domain. (910 aa)
AFZ49116.1PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (219 aa)
AFZ49146.1Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; PFAM: Bacterial regulatory proteins, luxR family. (90 aa)
AFZ49172.1PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (238 aa)
AFZ49286.1Mg chelatase-related protein; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein. (508 aa)
AFZ49298.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (252 aa)
AFZ49405.1Phosphoketolase; PFAM: XFP N-terminal domain; D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase. (732 aa)
AFZ49432.1PFAM: HAMP domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain. (735 aa)
AFZ49455.1PFAM: Vacuole effluxer Atg22 like. (535 aa)
AFZ49456.1PFAM: Late competence development protein ComFB; manually curated. (105 aa)
AFZ49458.1Hypothetical protein. (57 aa)
cpdAPutative phosphohydrolase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (266 aa)
AFZ49571.1Chemotaxis protein histidine kinase-like protein; PFAM: Hpt domain. (308 aa)
AFZ49597.1TIGRFAM: conserved hypothetical protein (putative transposase or invertase). (278 aa)
AFZ49598.1Hypothetical protein. (277 aa)
AFZ49672.1Hypothetical protein. (141 aa)
AFZ49827.1PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA. (368 aa)
AFZ49882.1Type II secretory pathway, component PulF; PFAM: Bacterial type II secretion system protein F domain. (406 aa)
AFZ49883.1PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT. (371 aa)
AFZ49884.1Hypothetical protein. (37 aa)
AFZ49885.1Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain. (672 aa)
AFZ49964.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (380 aa)
AFZ50020.1PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. (73 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (347 aa)
AFZ50022.1Hypothetical protein. (81 aa)
thiGGlycine oxidase ThiO; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (657 aa)
AFZ50151.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (225 aa)
AFZ50179.1Hypothetical protein. (70 aa)
AFZ50180.1PFAM: Adenylate and Guanylate cyclase catalytic domain; FHA domain. (552 aa)
AFZ50181.1Hypothetical protein. (56 aa)
AFZ50182.1Hypothetical protein. (29 aa)
AFZ50183.1Putative oxidoreductase, aryl-alcohol dehydrogenase like protein; PFAM: Aldo/keto reductase family. (321 aa)
AFZ50184.1Hypothetical protein. (120 aa)
AFZ50188.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (248 aa)
AFZ50249.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (224 aa)
AFZ50250.1PFAM: Protein of unknown function (DUF820). (191 aa)
AFZ50251.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (226 aa)
AFZ50256.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain. (363 aa)
AFZ50356.1PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein; Belongs to the UPF0102 family. (129 aa)
AFZ50366.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (434 aa)
AFZ50369.1KaiB domain-containing protein; PFAM: KaiB domain. (231 aa)
AFZ50370.1PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT. (429 aa)
AFZ50393.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (244 aa)
AFZ50504.1Serine phosphatase RsbU, regulator of sigma subunit; PFAM: Stage II sporulation protein E (SpoIIE). (467 aa)
AFZ50562.1PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase. (266 aa)
AFZ50626.1Prepilin signal peptidase PulO-like peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (268 aa)
AFZ50627.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (250 aa)
AFZ50628.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (444 aa)
AFZ50681.1Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain. (184 aa)
AFZ50707.1TIGRFAM: conserved hypothetical protein (putative transposase or invertase). (118 aa)
AFZ50755.1PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (241 aa)
AFZ50780.1Anti-sigma regulatory factor (Ser/Thr protein kinase). (140 aa)
AFZ50906.1Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; PFAM: GAF domain; Bacterial regulatory proteins, luxR family. (370 aa)
AFZ50916.1Putative amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein. (220 aa)
AFZ50938.1PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (374 aa)
AFZ50971.1Hypothetical protein. (112 aa)
AFZ50972.1PFAM: Response regulator receiver domain; Protein of unknown function (DUF3685). (566 aa)
AFZ51003.1PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain. (173 aa)
AFZ51004.1PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: general secretion pathway protein G; prepilin-type N-terminal cleavage/methylation domain. (167 aa)
AFZ51018.1Putative sensor protein/domain protein; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Predicted domain in sensory proteins (DUF2308). (647 aa)
AFZ51029.1PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (212 aa)
sfsAPFAM: Sugar fermentation stimulation protein; TIGRFAM: sugar fermentation stimulation protein; Belongs to the SfsA family. (244 aa)
AFZ51084.1PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; Belongs to the anti-sigma-factor antagonist family. (110 aa)
AFZ51102.1PAS domain S-box; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (666 aa)
AFZ51136.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (485 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (458 aa)
AFZ51269.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (225 aa)
AFZ51270.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (453 aa)
cofHRadical SAM domain protein, CofH subfamily; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (385 aa)
AFZ51423.1Bacteriophytochrome (light-regulated signal transduction histidine kinase); PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; CHASE3 domain. (468 aa)
AFZ51424.1PFAM: Response regulator receiver domain. (149 aa)
AFZ51425.1PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box. (914 aa)
AFZ51525.1PFAM: Competence protein; TIGRFAM: ComEC/Rec2-related protein. (723 aa)
AFZ51561.1PFAM: S23 ribosomal protein. (120 aa)
AFZ51580.1PFAM: Protein of unknown function, DUF1537. (441 aa)
AFZ51599.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; CHASE3 domain. (472 aa)
AFZ51600.1PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. (227 aa)
AFZ51635.1Hypothetical protein. (1546 aa)
AFZ51636.1TIGRFAM: prepilin-type N-terminal cleavage/methylation domain. (232 aa)
AFZ51637.1TIGRFAM: prepilin-type N-terminal cleavage/methylation domain. (335 aa)
AFZ51638.1Hypothetical protein. (177 aa)
AFZ51683.1Type II secretory pathway, component HofQ; PFAM: Bacterial type II/III secretion system short domain; Secretin and TonB N terminus short domain; Localisation of periplasmic protein complexes; Bacterial type II and III secretion system protein. (716 aa)
AFZ51684.1Hypothetical protein. (253 aa)
AFZ51685.1PFAM: Fimbrial assembly protein (PilN). (258 aa)
AFZ51686.1PFAM: Competence protein A; TIGRFAM: type IV pilus assembly protein PilM. (371 aa)
sasAHistidine kinase,KaiB domain-containing protein,histidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. (366 aa)
AFZ51758.1Histidine kinase,HAMP domain-containing protein,histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; TIGRFAM: heavy metal sensor kinase. (512 aa)
AFZ51963.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain. (928 aa)
AFZ51971.1Chemotaxis signal transduction protein; PFAM: CheW-like domain. (180 aa)
AFZ51972.1PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain. (714 aa)
AFZ52117.1PFAM: His Kinase A (phosphoacceptor) domain. (453 aa)
AFZ52118.1Glutaredoxin, GrxC family; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (115 aa)
Your Current Organism:
Dactylococcopsis salina
NCBI taxonomy Id: 13035
Other names: D. salina PCC 8305, Dactylococcopsis salina PCC 8305, Dactylococcopsis sp. PCC 8305, Myxobactron salinum PCC 8305
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