37 items (Pseudozyma hubeiensis) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	PHSY_001774	Uncharacterized protein. (563 aa)
	PHSY_001672	Ubiquitin fusion degradation protein. (426 aa)
	PHSY_001391	Histone H1. (206 aa)
	PHSY_001373	AAA domain-containing protein. (757 aa)
	PHSY_001201	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (440 aa)
	PHSY_001194	Plus3 domain-containing protein. (599 aa)
	PHSY_001006	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (992 aa)
	PHSY_003868	DNA helicase. (907 aa)
	PHSY_000517	PINc domain-containing protein. (1451 aa)
	PHSY_000355	DNA helicase; Belongs to the MCM family. (731 aa)
	PHSY_000072	DNA helicase I. (1145 aa)
	PHSY_004533	Uncharacterized protein. (879 aa)
	PHSY_004688	SMK-1 domain-containing protein. (1200 aa)
	PHSY_005097	Uncharacterized protein. (238 aa)
	PHSY_005222	Uncharacterized protein. (292 aa)
	PHSY_005442	Vezatin domain-containing protein. (1366 aa)
	PHSY_005788	DNA repair helicase. (849 aa)
	PHSY_006132	WD_REPEATS_REGION domain-containing protein. (614 aa)
	PHSY_003076	Kinase complex regulatory subunit. (777 aa)
	PHSY_006574	Bromo domain-containing protein. (800 aa)
	PHSY_006768	Uncharacterized protein. (679 aa)
	PHSY_007075	ER-associated protein catabolism-related protein. (736 aa)
	PHSY_004130	DNA helicase; Belongs to the MCM family. (959 aa)
	PHSY_004740	Potential phosphatidylinositol kinase; Belongs to the PI3/PI4-kinase family. (2719 aa)
	PHSY_004770	DNA repair protein RAD50. (1309 aa)
	PHSY_005121	Replication fork protection complex subunit. (1298 aa)
	PHSY_000711	Uncharacterized protein. (249 aa)
	PHSY_003104	DNA helicase; Belongs to the MCM family. (978 aa)
	PHSY_002838	Potential mRNA deadenylase. (661 aa)
	PHSY_002475	Potential ubiquitin-protein ligase. (2047 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (850 aa)
	PHSY_006800	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1313 aa)
	PHSY_007358	Likely anaphase-promoting complex subunit Cdc16. (1068 aa)
	PHSY_004513	Serine/threonine-protein phosphatase. (305 aa)
	PHSY_003907	DNA helicase; Belongs to the MCM family. (1014 aa)
	PHSY_000576	Uncharacterized protein. (897 aa)
	PHSY_003801	WD_REPEATS_REGION domain-containing protein. (805 aa)

Your Current Organism:

Pseudozyma hubeiensis

NCBI taxonomy Id: 1305764
Other names: P. hubeiensis SY62, Pseudozyma hubeiensis SY62

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	PHSY_000355	R9P1A7	R9NWB2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PHSY_001201	R9P1A7	R9NYA5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.899
MCM7	PHSY_001373	R9P1A7	R9NYG0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	AAA domain-containing protein.	0.998
MCM7	PHSY_001672	R9P1A7	R9NZ34	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Ubiquitin fusion degradation protein.	0.469
MCM7	PHSY_003076	R9P1A7	R9PBP5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Kinase complex regulatory subunit.	0.989
MCM7	PHSY_003104	R9P1A7	R9P2B4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PHSY_003868	R9P1A7	R9P4D5	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase.	0.999
MCM7	PHSY_003907	R9P1A7	R9P545	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PHSY_004130	R9P1A7	R9PEM0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PHSY_004740	R9P1A7	R9PGB7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Potential phosphatidylinositol kinase; Belongs to the PI3/PI4-kinase family.	0.702
MCM7	PHSY_005121	R9P1A7	R9PHF3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication fork protection complex subunit.	0.958
MCM7	PHSY_005442	R9P1A7	R9P946	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Vezatin domain-containing protein.	0.899
MCM7	PHSY_006800	R9P1A7	R9PM47	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.403
MCM7	PHSY_007075	R9P1A7	R9PDL3	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	ER-associated protein catabolism-related protein.	0.445
PHSY_000072	PHSY_001006	R9NVK7	R9NXV4	DNA helicase I.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.667
PHSY_000072	PHSY_001201	R9NVK7	R9NYA5	DNA helicase I.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.650
PHSY_000072	PHSY_004740	R9NVK7	R9PGB7	DNA helicase I.	Potential phosphatidylinositol kinase; Belongs to the PI3/PI4-kinase family.	0.528
PHSY_000072	PHSY_004770	R9NVK7	R9PGF2	DNA helicase I.	DNA repair protein RAD50.	0.567
PHSY_000072	PHSY_005121	R9NVK7	R9PHF3	DNA helicase I.	Replication fork protection complex subunit.	0.460
PHSY_000072	PHSY_005442	R9NVK7	R9P946	DNA helicase I.	Vezatin domain-containing protein.	0.650