node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PHSY_000590 | PHSY_001006 | R9NWU8 | R9NXV4 | DUF1767 domain-containing protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.995 |
PHSY_000590 | PHSY_001380 | R9NWU8 | R9P6X0 | DUF1767 domain-containing protein. | Protein kinase domain-containing protein. | 0.464 |
PHSY_000590 | PHSY_001431 | R9NWU8 | R9NYS2 | DUF1767 domain-containing protein. | zf-4CXXC_R1 domain-containing protein. | 0.488 |
PHSY_000590 | PHSY_001576 | R9NWU8 | R9NZ90 | DUF1767 domain-containing protein. | SAE2 domain-containing protein. | 0.668 |
PHSY_000590 | PHSY_003187 | R9NWU8 | R9P2Q1 | DUF1767 domain-containing protein. | Uncharacterized protein. | 0.718 |
PHSY_000590 | PHSY_003312 | R9NWU8 | R9P316 | DUF1767 domain-containing protein. | zf-4CXXC_R1 domain-containing protein. | 0.488 |
PHSY_000590 | PHSY_003357 | R9NWU8 | R9P362 | DUF1767 domain-containing protein. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.935 |
PHSY_000590 | PHSY_004740 | R9NWU8 | R9PGB7 | DUF1767 domain-containing protein. | Potential phosphatidylinositol kinase; Belongs to the PI3/PI4-kinase family. | 0.733 |
PHSY_000590 | PHSY_005028 | R9NWU8 | R9P872 | DUF1767 domain-containing protein. | Uncharacterized protein. | 0.972 |
PHSY_000590 | PHSY_005177 | R9NWU8 | R9P894 | DUF1767 domain-containing protein. | Uncharacterized protein. | 0.935 |
PHSY_000590 | PHSY_005809 | R9NWU8 | R9PJC6 | DUF1767 domain-containing protein. | Other/HAL protein kinase. | 0.418 |
PHSY_000590 | PHSY_006562 | R9NWU8 | R9PLJ2 | DUF1767 domain-containing protein. | 3'-5' exonuclease domain-containing protein. | 0.993 |
PHSY_000590 | PHSY_007048 | R9NWU8 | R9PDY1 | DUF1767 domain-containing protein. | Other/HAL protein kinase. | 0.418 |
PHSY_001006 | PHSY_000590 | R9NXV4 | R9NWU8 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DUF1767 domain-containing protein. | 0.995 |
PHSY_001006 | PHSY_001380 | R9NXV4 | R9P6X0 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Protein kinase domain-containing protein. | 0.563 |
PHSY_001006 | PHSY_001431 | R9NXV4 | R9NYS2 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | zf-4CXXC_R1 domain-containing protein. | 0.519 |
PHSY_001006 | PHSY_001576 | R9NXV4 | R9NZ90 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | SAE2 domain-containing protein. | 0.665 |
PHSY_001006 | PHSY_003187 | R9NXV4 | R9P2Q1 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Uncharacterized protein. | 0.665 |
PHSY_001006 | PHSY_003312 | R9NXV4 | R9P316 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | zf-4CXXC_R1 domain-containing protein. | 0.519 |
PHSY_001006 | PHSY_003357 | R9NXV4 | R9P362 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.939 |