node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AOZ98207.1 | AOZ98241.1 | BIW12_01420 | BIW12_01630 | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
AOZ98207.1 | AOZ98797.1 | BIW12_01420 | BIW12_04755 | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.598 |
AOZ98207.1 | APA00504.1 | BIW12_01420 | BIW12_14325 | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.958 |
AOZ98207.1 | APA00507.1 | BIW12_01420 | BIW12_14345 | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.460 |
AOZ98207.1 | APA00508.1 | BIW12_01420 | BIW12_14350 | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.403 |
AOZ98207.1 | APA01034.1 | BIW12_01420 | BIW12_14340 | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.607 |
AOZ98207.1 | ilvA | BIW12_01420 | BIW12_10680 | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.881 |
AOZ98207.1 | ilvD | BIW12_01420 | BIW12_04345 | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.967 |
AOZ98207.1 | ilvD-2 | BIW12_01420 | BIW12_14335 | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.967 |
AOZ98207.1 | leuC | BIW12_01420 | BIW12_04745 | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.415 |
AOZ98241.1 | AOZ98207.1 | BIW12_01630 | BIW12_01420 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Branched chain amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.900 |
AOZ98241.1 | AOZ98797.1 | BIW12_01630 | BIW12_04755 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.598 |
AOZ98241.1 | APA00504.1 | BIW12_01630 | BIW12_14325 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.958 |
AOZ98241.1 | APA00507.1 | BIW12_01630 | BIW12_14345 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.460 |
AOZ98241.1 | APA00508.1 | BIW12_01630 | BIW12_14350 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.403 |
AOZ98241.1 | APA01034.1 | BIW12_01630 | BIW12_14340 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.607 |
AOZ98241.1 | ilvA | BIW12_01630 | BIW12_10680 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.881 |
AOZ98241.1 | ilvD | BIW12_01630 | BIW12_04345 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.967 |
AOZ98241.1 | ilvD-2 | BIW12_01630 | BIW12_14335 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.967 |
AOZ98241.1 | leuC | BIW12_01630 | BIW12_04745 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.415 |