STRINGSTRING
lacR_2 lacR_2 AKZ49961.1 AKZ49961.1 AKZ49962.1 AKZ49962.1 AKZ49963.1 AKZ49963.1 lacA lacA lacB lacB AKZ49966.1 AKZ49966.1 lacD lacD AKZ50156.1 AKZ50156.1 apbA apbA FruR FruR pfkB pfkB FruA FruA lacG lacG LacE LacE LacF LacF lacD-2 lacD-2 LacC2 LacC2 lacB-2 lacB-2 lacA-2 lacA-2 AKZ51144.1 AKZ51144.1 LacR2 LacR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lacR_2DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
AKZ49961.1PTS galactose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
AKZ49962.1PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
AKZ49963.1PTS galactitol transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
lacAGalactose-6-phosphate isomerase; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
lacBGalactose-6-phosphate isomerase; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
AKZ49966.1Tagatose-6-phosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
lacDTagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
AKZ50156.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
apbA2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (307 aa)
FruRDeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
pfkBPhosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
FruAPTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (648 aa)
lacG6-phospho-beta-galactosidase; Catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
LacEPTS system lactose-specific transporter subunits IICB; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
LacFPTS system lactose-specific transporter subunit IIA; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
lacD-2Tagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
LacC2Tagatose-6-phosphate kinase; Catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
lacB-2Galactose-6-phosphate isomerase; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
lacA-2Galactose-6-phosphate isomerase; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
AKZ51144.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (84 aa)
LacR2DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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