(8 nodes) ATPase-coupled ion transmembrane transporter activity network (Streptococcus pyogenes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Your Input:
	NtpI	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (666 aa)
	ntpK	ATP synthase subunit K; Produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase proteolipid subunit family. (159 aa)
	NtpE	Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
	NtpC	ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
	NtpF	ATP synthase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa)
	NtpA	Produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)
	ntpB	ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (471 aa)
	atpD	ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (208 aa)

Your Current Organism:

Streptococcus pyogenes

NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NtpA	NtpC	SD89_00875	SD89_00865	Produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
NtpA	NtpE	SD89_00875	SD89_00860	Produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.	Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
NtpA	NtpF	SD89_00875	SD89_00870	Produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
NtpA	NtpI	SD89_00875	SD89_00850	Produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
NtpA	atpD	SD89_00875	SD89_00885	Produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
NtpA	ntpB	SD89_00875	SD89_00880	Produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.	0.999
NtpA	ntpK	SD89_00875	SD89_00855	Produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit K; Produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase proteolipid subunit family.	0.999
NtpC	NtpA	SD89_00865	SD89_00875	ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	Produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
NtpC	NtpE	SD89_00865	SD89_00860	ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
NtpC	NtpF	SD89_00865	SD89_00870	ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
NtpC	NtpI	SD89_00865	SD89_00850	ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
NtpC	atpD	SD89_00865	SD89_00885	ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
NtpC	ntpB	SD89_00865	SD89_00880	ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.	0.999
NtpC	ntpK	SD89_00865	SD89_00855	ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit K; Produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the V-ATPase proteolipid subunit family.	0.999
NtpE	NtpA	SD89_00860	SD89_00875	Derived by automated computational analysis using gene prediction method: Protein Homology.	Produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
NtpE	NtpC	SD89_00860	SD89_00865	Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
NtpE	NtpF	SD89_00860	SD89_00870	Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
NtpE	NtpI	SD89_00860	SD89_00850	Derived by automated computational analysis using gene prediction method: Protein Homology.	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
NtpE	atpD	SD89_00860	SD89_00885	Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.999
NtpE	ntpB	SD89_00860	SD89_00880	Derived by automated computational analysis using gene prediction method: Protein Homology.	ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.	0.999

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