STRINGSTRING
dusB dusB tgt tgt truA truA tsaB tsaB tsaD tsaD tsaE tsaE trmB trmB AKZ50075.1 AKZ50075.1 miaA miaA hflX hflX AKZ50217.1 AKZ50217.1 rnz rnz AKZ50219.1 AKZ50219.1 AKZ50224.1 AKZ50224.1 AKZ50225.1 AKZ50225.1 AKZ50226.1 AKZ50226.1 queA queA queG queG yeeN yeeN mnmA mnmA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dusBTIM barrel oxidoreductase NifR3; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (325 aa)
tgtQueuine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
truAPseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
tsaBPeptidase M22; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
tsaDtRNA threonylcarbamoyladenosine biosynthesis protein Gcp; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (342 aa)
tsaEHydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
trmBtRNA (guanine-N7)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (211 aa)
AKZ50075.1Queuosine transporter QueT; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
hflXGTP-binding protein HflX; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
AKZ50217.1Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (309 aa)
AKZ50219.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
AKZ50224.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
AKZ50225.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
AKZ50226.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
queAS-adenosylmethionine tRNA ribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
queGEpoxyqueuosine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
yeeNHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
mnmAThiouridylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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