node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKZ49602.1 | AKZ50334.1 | SD89_00275 | SD89_04295 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Xanthine permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.633 |
AKZ49602.1 | AKZ51338.1 | SD89_00275 | SD89_00270 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.981 |
AKZ49602.1 | PurA | SD89_00275 | SD89_00900 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.949 |
AKZ49602.1 | PurM | SD89_00275 | SD89_00285 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
AKZ49602.1 | apt | SD89_00275 | SD89_03695 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.663 |
AKZ49602.1 | gmk | SD89_00275 | SD89_02565 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.644 |
AKZ49602.1 | guaA | SD89_00275 | SD89_04575 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.970 |
AKZ49602.1 | guaB | SD89_00275 | SD89_09625 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.891 |
AKZ49602.1 | guaC | SD89_00275 | SD89_04285 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.670 |
AKZ49602.1 | purB | SD89_00275 | SD89_00325 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.949 |
AKZ49602.1 | purD | SD89_00275 | SD89_00305 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.995 |
AKZ49602.1 | purE | SD89_00275 | SD89_00310 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosyl carboxyaminoimidazole mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.949 |
AKZ49602.1 | purF | SD89_00275 | SD89_00280 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.980 |
AKZ49602.1 | purK | SD89_00275 | SD89_00315 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazole carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.949 |
AKZ49602.1 | xpt | SD89_00275 | SD89_04290 | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.663 |
AKZ50334.1 | AKZ49602.1 | SD89_04295 | SD89_00275 | Xanthine permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.633 |
AKZ50334.1 | guaA | SD89_04295 | SD89_04575 | Xanthine permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.503 |
AKZ50334.1 | guaC | SD89_04295 | SD89_04285 | Xanthine permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.637 |
AKZ50334.1 | purE | SD89_04295 | SD89_00310 | Xanthine permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosyl carboxyaminoimidazole mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.505 |
AKZ50334.1 | xpt | SD89_04295 | SD89_04290 | Xanthine permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.979 |