STRINGSTRING
AdcR AdcR srtB srtB gap gap glnA glnA eno eno srtA srtA srtF srtF SrtE SrtE PulA PulA guaB guaB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AdcRMarR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
srtBSortase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Also binds human plasminogen. (336 aa)
glnAGlutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
srtALantibiotic streptin; Lanthionine-containing peptide antibiotic (lantibiotic) active on certain Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. (46 aa)
srtFLantibiotic ABC transporter ATP-binding protein; Implicated in the export process of the lantibiotic SrtA. (229 aa)
SrtELantibiotic ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
PulAAmylopullulanase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1165 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (493 aa)
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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