STRINGSTRING
Shp Shp isdE isdE FhuB FhuB hup hup srtB srtB FhuC FhuC srtA srtA AKZ50997.1 AKZ50997.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ShpHeme-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
isdEABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
FhuBFerrichrome ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (350 aa)
hupDNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation. (91 aa)
srtBSortase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
FhuCIron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
srtALantibiotic streptin; Lanthionine-containing peptide antibiotic (lantibiotic) active on certain Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. (46 aa)
AKZ50997.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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