node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RpoA | gyrA | SD89_00500 | SD89_04370 | DNA-directed RNA polymerase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.768 |
RpoA | pyrG | SD89_00500 | SD89_01505 | DNA-directed RNA polymerase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.628 |
RpoA | rpoB | SD89_00500 | SD89_00635 | DNA-directed RNA polymerase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
RpoA | rpoC | SD89_00500 | SD89_00640 | DNA-directed RNA polymerase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
RpoA | rpsA | SD89_00500 | SD89_03635 | DNA-directed RNA polymerase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S1; In Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.938 |
RpoA | rpsL | SD89_00500 | SD89_01320 | DNA-directed RNA polymerase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.979 |
gyrA | RpoA | SD89_04370 | SD89_00500 | DNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.768 |
gyrA | rpoB | SD89_04370 | SD89_00635 | DNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |
gyrA | rpoC | SD89_04370 | SD89_00640 | DNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.694 |
gyrA | rpsA | SD89_04370 | SD89_03635 | DNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S1; In Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.585 |
gyrA | rpsL | SD89_04370 | SD89_01320 | DNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.876 |
gyrA | rsmG | SD89_04370 | SD89_08405 | DNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | 16S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.529 |
pyrG | RpoA | SD89_01505 | SD89_00500 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | DNA-directed RNA polymerase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.628 |
pyrG | rpoB | SD89_01505 | SD89_00635 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.888 |
pyrG | rpoC | SD89_01505 | SD89_00640 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.667 |
pyrG | rpsA | SD89_01505 | SD89_03635 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 30S ribosomal protein S1; In Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.496 |
pyrG | rpsL | SD89_01505 | SD89_01320 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.400 |
pyrG | thyA | SD89_01505 | SD89_03480 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.681 |
rpoB | RpoA | SD89_00635 | SD89_00500 | DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
rpoB | gyrA | SD89_00635 | SD89_04370 | DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |