STRINGSTRING
AKZ50938.1 AKZ50938.1 adhP adhP rpoB rpoB ackA ackA pgi pgi Rpe Rpe pgk pgk pflB pflB ScrA ScrA glpK glpK AKZ49984.1 AKZ49984.1 tkt tkt AKZ49994.1 AKZ49994.1 LacZ LacZ gyrB gyrB eno eno FruA FruA rpiA rpiA gyrB-2 gyrB-2 eutD eutD ldh ldh arlR arlR pyk pyk DeaD2 DeaD2 GapN GapN DeaD DeaD gpmA_2 gpmA_2 typA typA rbsR rbsR AKZ50888.1 AKZ50888.1 PtsK PtsK ccpA ccpA lctO lctO csrR csrR AKZ51190.1 AKZ51190.1 PflD PflD ahpC ahpC ahpF ahpF recA recA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKZ50938.1PTS beta-glucoside transporter subunit IIABC; Derived by automated computational analysis using gene prediction method: Protein Homology. (620 aa)
adhPEthanol-active dehydrogenase/acetaldehyde-active reductase; Similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
rpoBDNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (1188 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
pgiGlucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
RpeRibulose-phosphate 3-epimerase; Catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
pflBFormate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (775 aa)
ScrAPTS sucrose transporter subunit IIABC; Derived by automated computational analysis using gene prediction method: Protein Homology. (627 aa)
glpKConverts glycerol and ADP to glycerol-3-phosphate and ADP; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa)
AKZ49984.1NADH peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
tktTransketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (661 aa)
AKZ49994.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
LacZBeta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1138 aa)
gyrBDNA gyrase subunit B; Negatively supercoils closed circular double-stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (650 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)
FruAPTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (648 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (227 aa)
gyrB-2DNA gyrase subunit B; Negatively supercoils closed circular double-stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (649 aa)
eutDPhosphotransacetylase; In Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (327 aa)
arlRTranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
pykPyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
DeaD2RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
GapNGlyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
DeaDRNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (539 aa)
gpmA_2Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (231 aa)
typAGTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. (613 aa)
rbsRLacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
AKZ50888.1Acetoin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
PtsKSerine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
ccpACatabolite control protein A; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
lctOLactate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
csrRPhoB family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
AKZ51190.1PTS system glucose/maltose-specific transporter subunit IIBCA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (728 aa)
PflDFormate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (805 aa)
ahpCAlkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (186 aa)
ahpFNADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
recARecombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (378 aa)
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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