STRINGSTRING
pgi pgi galU galU nanE nanE NanH NanH ScrK ScrK manA manA manN manN ManM ManM manX manX nagA nagA murA murA glmM glmM AKZ50264.1 AKZ50264.1 agaC_2 agaC_2 PtsD PtsD murB murB PgmA PgmA glmS glmS AKZ50629.1 AKZ50629.1 murA-2 murA-2 nagB nagB GlcK GlcK AKZ50961.1 AKZ50961.1 hasB hasB hasC hasC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pgiGlucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
galUUTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
nanEN-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (234 aa)
NanHN-acetylneuraminate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
ScrKFructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
manAMannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family. (317 aa)
manNPTS system mannose family transporter subunit IID; Hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
ManMPTS mannose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
manXPTS system mannost-specific transporter subunits IIAB; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (423 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (451 aa)
AKZ50264.1PTS mannnose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
agaC_2PTS mannnose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
PtsDPTS mannnose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
PgmAPhosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (604 aa)
AKZ50629.1Beta-hexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa)
nagBGlucosamine-6-phosphate deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
GlcKGlucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
AKZ50961.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
hasBUDP-glucose 6-dehydrogenase; Catalyzes the formation of UDP-glucuronic acid which is required for capsular hyaluronic acid synthesis. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (402 aa)
hasCUTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDPGP type 2 family. (304 aa)
Your Current Organism:
Streptococcus pyogenes
NCBI taxonomy Id: 1314
Other names: ATCC 12344, CCUG 12701, CCUG 4207, CIP 56.41, DSM 20565, JCM 5674, LMG 14700, LMG:14700, Micrococcus scarlatinae, NCAIM B.01705, NCTC 8198, S. pyogenes, Streptococcus erysipelatos, Streptococcus hemolyticus, Streptococcus scarlatinae
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