(59 nodes) Propanoate metabolism network (Peniophora sp. CONT)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A166D565	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (449 aa)
	A0A166D9H3	Uncharacterized protein. (568 aa)
	A0A166DGH0	Uncharacterized protein. (682 aa)
	A0A166DKM3	S-adenosyl-L-methionine-dependent methyltransferase. (401 aa)
	A0A166DME8	Uncharacterized protein. (672 aa)
	A0A166EII1	GroES-like protein. (380 aa)
	A0A166ENR7	Uncharacterized protein. (188 aa)
	A0A166ENS4	Uncharacterized protein. (264 aa)
	A0A166ENU1	Uncharacterized protein. (383 aa)
	A0A166EVF9	Acyl-CoA dehydrogenase NM domain-like protein. (567 aa)
	A0A166FDY8	Sec63-domain-containing protein. (1455 aa)
	A0A166FQ37	Dihydrolipoyl dehydrogenase. (505 aa)
	A0A166FTZ3	RING-type domain-containing protein. (218 aa)
	A0A166FU38	Uncharacterized protein. (238 aa)
	A0A166FU58	Uncharacterized protein. (143 aa)
	A0A166FU67	RING-type domain-containing protein. (242 aa)
	A0A166G1L3	Phosphoenolpyruvate/pyruvate domain-containing protein. (303 aa)
	A0A166GD80	Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (277 aa)
	A0A166GJ31	Acetyl-coenzyme A synthetase. (662 aa)
	A0A166GKK0	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (329 aa)
	A0A166GXB0	D-lactaldehyde dehydrogenase. (346 aa)
	A0A166HHX5	Uncharacterized protein. (790 aa)
	A0A166I4C9	Acyl-CoA dehydrogenase NM domain-like protein. (581 aa)
	A0A166IBN3	2-methylcitrate dehydratase. (482 aa)
	A0A166KTL2	NAD-P-binding protein. (346 aa)
	A0A166IDR6	Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
	A0A166IF04	Pyruvate dehydrogenase. (471 aa)
	A0A166IVG3	D-lactaldehyde dehydrogenase. (340 aa)
	A0A166IZI1	Phosphoenolpyruvate pyruvate domain-containing protein. (334 aa)
	A0A166M2G8	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (417 aa)
	A0A166K843	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	A0A166JID3	Multifunctional beta-oxidation protein. (898 aa)
	A0A166K291	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (515 aa)
	A0A166JZL3	SET domain-containing protein. (429 aa)
	A0A165W6Y5	Uncharacterized protein. (250 aa)
	A0A165XE90	Acetyl CoA carboxylase. (2233 aa)
	A0A165XNB1	Uncharacterized protein. (979 aa)
	A0A165Y3C6	NAD-P-binding protein. (341 aa)
	A0A165YCE6	Uncharacterized protein. (699 aa)
	A0A165YKG9	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (683 aa)
	A0A165YR81	NAD(P)-binding protein. (349 aa)
	A0A165YR94	D-lactaldehyde dehydrogenase. (349 aa)
	A0A165YUK6	Methylmalonate-semialdehyde dehydrogenase. (541 aa)
	A0A165YUW7	Uncharacterized protein. (420 aa)
	A0A165Z447	P-loop containing nucleoside triphosphate hydrolase protein. (1564 aa)
	A0A165ZE09	S-adenosyl-L-methionine-dependent methyltransferase. (287 aa)
	A0A165ZE19	S-adenosyl-L-methionine-dependent methyltransferase. (280 aa)
	A0A165ZJB9	Probable acetate kinase. (428 aa)
	A0A166A4H5	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (288 aa)
	A0A166BE32	NAD(P)-binding protein. (341 aa)
	A0A166BE44	NAD-P-binding protein. (330 aa)
	A0A166BEW6	SET domain-containing protein. (503 aa)
	A0A166BSJ5	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (486 aa)
	A0A166CAB9	NAD(P)-binding protein. (340 aa)
	A0A166CMT0	GroES-like protein. (449 aa)
	A0A166CW92	NAD-P-binding protein. (339 aa)
	A0A166CWI1	NAD(P)-binding protein. (335 aa)
	A0A166CWM3	D-lactaldehyde dehydrogenase. (341 aa)
	A0A166CWN0	D-lactaldehyde dehydrogenase. (350 aa)

Your Current Organism:

Peniophora sp. CONT

NCBI taxonomy Id: 1314672
Other names: P. sp. CONT

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A165W6Y5	A0A165XE90	Uncharacterized protein.	Acetyl CoA carboxylase.	0.565
A0A165W6Y5	A0A165XNB1	Uncharacterized protein.	Uncharacterized protein.	0.565
A0A165W6Y5	A0A165YKG9	Uncharacterized protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.844
A0A165W6Y5	A0A165YUK6	Uncharacterized protein.	Methylmalonate-semialdehyde dehydrogenase.	0.781
A0A165W6Y5	A0A166BSJ5	Uncharacterized protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.743
A0A165W6Y5	A0A166D9H3	Uncharacterized protein.	Uncharacterized protein.	0.722
A0A165W6Y5	A0A166EVF9	Uncharacterized protein.	Acyl-CoA dehydrogenase NM domain-like protein.	0.722
A0A165W6Y5	A0A166GJ31	Uncharacterized protein.	Acetyl-coenzyme A synthetase.	0.636
A0A165W6Y5	A0A166GKK0	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.566
A0A165W6Y5	A0A166I4C9	Uncharacterized protein.	Acyl-CoA dehydrogenase NM domain-like protein.	0.722
A0A165W6Y5	A0A166JID3	Uncharacterized protein.	Multifunctional beta-oxidation protein.	0.696
A0A165W6Y5	A0A166K291	Uncharacterized protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.761
A0A165W6Y5	A0A166K843	Uncharacterized protein.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.912
A0A165W6Y5	A0A166M2G8	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.450
A0A165XE90	A0A165W6Y5	Acetyl CoA carboxylase.	Uncharacterized protein.	0.565
A0A165XE90	A0A165YKG9	Acetyl CoA carboxylase.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.550
A0A165XE90	A0A165YUK6	Acetyl CoA carboxylase.	Methylmalonate-semialdehyde dehydrogenase.	0.657
A0A165XE90	A0A165Z447	Acetyl CoA carboxylase.	P-loop containing nucleoside triphosphate hydrolase protein.	0.406
A0A165XE90	A0A166A4H5	Acetyl CoA carboxylase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.589
A0A165XE90	A0A166BSJ5	Acetyl CoA carboxylase.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.565