(41 nodes) Ubiquitin-dependent ERAD pathway network (Sodiomyces alkalinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A3N2PJN1	Long chronological lifespan protein 2; Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway. (125 aa)
	A0A3N2PKC2	HECT-domain-containing protein. (1176 aa)
	A0A3N2PKF4	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (527 aa)
	A0A3N2PL29	DUF1977-domain-containing protein. (360 aa)
	A0A3N2PLF2	ANK_REP_REGION domain-containing protein. (652 aa)
	A0A3N2PLH9	Ubiquitin conjugation factor E4. (1100 aa)
	A0A3N2PMS9	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (797 aa)
	A0A3N2PNB1	UV excision repair protein Rad23. (390 aa)
	A0A3N2PNZ4	Hsp70-like protein; Belongs to the heat shock protein 70 family. (663 aa)
	A0A3N2PQI4	NPL4 family protein. (681 aa)
	A0A3N2PRM3	ARM repeat-containing protein. (1886 aa)
	A0A3N2PS12	26S proteasome subunit P45 family protein; Belongs to the AAA ATPase family. (391 aa)
	A0A3N2PT17	UBX domain-containing protein. (505 aa)
	A0A3N2PTR5	OTU-domain-containing protein. (371 aa)
	A0A3N2PUP5	TPR_REGION domain-containing protein. (928 aa)
	A0A3N2PUR6	RING-CH-type domain-containing protein. (1783 aa)
	A0A3N2PVB7	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (534 aa)
	A0A3N2PVM0	J domain-containing protein. (323 aa)
	A0A3N2PVP5	PRKCSH domain-containing protein. (552 aa)
	A0A3N2PWI7	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (246 aa)
	A0A3N2PWM8	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
	A0A3N2PWV1	Pre protein translocase. (476 aa)
	A0A3N2PX96	Uncharacterized protein. (141 aa)
	A0A3N2PXH4	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (260 aa)
	A0A3N2PYG4	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	A0A3N2PYM9	Uncharacterized protein. (296 aa)
	A0A3N2PZ41	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1107 aa)
	A0A3N2PZT9	TUG-UBL1 domain-containing protein. (494 aa)
	A0A3N2PZV1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (682 aa)
	A0A3N2Q019	Acetyltransferase. (190 aa)
	A0A3N2Q055	RING-type domain-containing protein. (815 aa)
	A0A3N2Q2P1	UBC-like protein. (319 aa)
	A0A3N2Q364	Small glutamine-rich tetratricopeptide repeat-containing protein 2-like protein. (345 aa)
	A0A3N2Q3A5	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (621 aa)
	A0A3N2Q3I9	DnaJ domain-containing protein. (418 aa)
	A0A3N2Q4N4	UBX domain-containing protein. (522 aa)
	A0A3N2Q6T0	HCP-like protein. (857 aa)
	A0A3N2Q7B8	Ubiquitin-conjugating enzyme. (269 aa)
	A0A3N2Q7S8	Cell division cycle protein; Belongs to the AAA ATPase family. (818 aa)
	A0A3N2Q9X4	Ubiquitin fusion degradation protein. (380 aa)
	A0A3N2QAA1	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (237 aa)

Your Current Organism:

Sodiomyces alkalinus

NCBI taxonomy Id: 1314773
Other names: Plectosphaerellaceae sp. AGG-2013 F11, S. alkalinus F11, Sodiomyces alkalinus F11

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A3N2PKC2	A0A3N2PLH9	HECT-domain-containing protein.	Ubiquitin conjugation factor E4.	0.650
A0A3N2PKC2	A0A3N2PNB1	HECT-domain-containing protein.	UV excision repair protein Rad23.	0.578
A0A3N2PKC2	A0A3N2PUR6	HECT-domain-containing protein.	RING-CH-type domain-containing protein.	0.453
A0A3N2PKC2	A0A3N2PYG4	HECT-domain-containing protein.	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.419
A0A3N2PKC2	A0A3N2QAA1	HECT-domain-containing protein.	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.450
A0A3N2PKF4	A0A3N2PMS9	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.559
A0A3N2PKF4	A0A3N2PVB7	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.636
A0A3N2PKF4	A0A3N2Q3A5	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.559
A0A3N2PL29	A0A3N2PLH9	DUF1977-domain-containing protein.	Ubiquitin conjugation factor E4.	0.422
A0A3N2PL29	A0A3N2PNZ4	DUF1977-domain-containing protein.	Hsp70-like protein; Belongs to the heat shock protein 70 family.	0.846
A0A3N2PL29	A0A3N2PUP5	DUF1977-domain-containing protein.	TPR_REGION domain-containing protein.	0.467
A0A3N2PL29	A0A3N2Q364	DUF1977-domain-containing protein.	Small glutamine-rich tetratricopeptide repeat-containing protein 2-like protein.	0.467
A0A3N2PL29	A0A3N2Q3I9	DUF1977-domain-containing protein.	DnaJ domain-containing protein.	0.640
A0A3N2PLF2	A0A3N2PLH9	ANK_REP_REGION domain-containing protein.	Ubiquitin conjugation factor E4.	0.646
A0A3N2PLF2	A0A3N2PQI4	ANK_REP_REGION domain-containing protein.	NPL4 family protein.	0.550
A0A3N2PLF2	A0A3N2Q4N4	ANK_REP_REGION domain-containing protein.	UBX domain-containing protein.	0.513
A0A3N2PLF2	A0A3N2Q7S8	ANK_REP_REGION domain-containing protein.	Cell division cycle protein; Belongs to the AAA ATPase family.	0.914
A0A3N2PLF2	A0A3N2Q9X4	ANK_REP_REGION domain-containing protein.	Ubiquitin fusion degradation protein.	0.535
A0A3N2PLH9	A0A3N2PKC2	Ubiquitin conjugation factor E4.	HECT-domain-containing protein.	0.650
A0A3N2PLH9	A0A3N2PL29	Ubiquitin conjugation factor E4.	DUF1977-domain-containing protein.	0.422