(87 nodes) Mixed, incl. Protein localization to mitochondrion, and Mitochondrial calcium ion transport network (Neolentinus lepideus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A165MU85	Zinc/iron permease. (546 aa)
	A0A165NCP8	Mitochondrial import inner membrane translocase subunit TIM9. (88 aa)
	A0A165NIF7	Uncharacterized protein. (142 aa)
	A0A165P8T2	ADP/ATP carrier receptor. (593 aa)
	MDM10	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (444 aa)
	A0A165PET2	NCS cytosine-purine permease; Belongs to the purine-cytosine permease (2.A.39) family. (506 aa)
	A0A165PGJ5	P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the AAA ATPase family. (489 aa)
	A0A165PH05	J domain-containing protein. (258 aa)
	A0A165PHJ2	Heat shock protein 70; Belongs to the heat shock protein 70 family. (664 aa)
	A0A165PHY1	Tim17-domain-containing protein. (182 aa)
	A0A165PIV6	DUF2263 domain-containing protein. (313 aa)
	A0A165PJB5	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (471 aa)
	A0A165PLS9	DDE_3 domain-containing protein. (69 aa)
	A0A165PLT9	Uncharacterized protein. (148 aa)
	A0A165PMF3	Uncharacterized protein. (135 aa)
	A0A165PPN3	P-loop containing nucleoside triphosphate hydrolase protein. (614 aa)
	A0A165PQX5	Uncharacterized protein. (163 aa)
	A0A165PW23	Uncharacterized protein. (83 aa)
	A0A165PX13	P-loop containing nucleoside triphosphate hydrolase protein. (546 aa)
	A0A165PX45	P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the AAA ATPase family. (564 aa)
	A0A165PX79	BCS1_N domain-containing protein. (249 aa)
	A0A165PYE8	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (89 aa)
	A0A165PYU8	Prohibitin. (273 aa)
	A0A165PZT3	zf-Tim10_DDP domain-containing protein. (102 aa)
	A0A165Q0Y7	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (371 aa)
	A0A165QB64	P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the AAA ATPase family. (620 aa)
	A0A165QRE3	Bac_surface_Ag domain-containing protein. (491 aa)
	A0A165R1A8	Uncharacterized protein. (124 aa)
	A0A165R6X5	Prohibitin. (293 aa)
	A0A165RBS5	DUF2263 domain-containing protein. (452 aa)
	A0A165RD14	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (216 aa)
	A0A165REN1	Uncharacterized protein. (132 aa)
	A0A165RFR4	Uncharacterized protein. (368 aa)
	A0A165RHH7	Uncharacterized protein. (100 aa)
	MDM12	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (321 aa)
	A0A165RMK1	Uncharacterized protein. (103 aa)
	A0A165RZI5	Uncharacterized protein. (91 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (693 aa)
	A0A165S287	Uncharacterized protein. (51 aa)
	A0A165S7U6	Uncharacterized protein. (541 aa)
	A0A165SGR7	Rhomboid domain-containing protein. (443 aa)
	A0A165SH72	DUF2263 domain-containing protein. (308 aa)
	A0A165SIZ8	Sulfhydryl oxidase. (193 aa)
	A0A165SWI5	Uncharacterized protein. (353 aa)
	A0A165T0G0	Uncharacterized protein; Belongs to the purine-cytosine permease (2.A.39) family. (532 aa)
	A0A165T0J9	Uncharacterized protein; Belongs to the purine-cytosine permease (2.A.39) family. (529 aa)
	A0A165T213	MCU domain-containing protein. (403 aa)
	A0A165T4J4	MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (90 aa)
	A0A165TAC9	DUF3074 domain-containing protein. (246 aa)
	A0A165TB53	LEA_2 domain-containing protein. (309 aa)
	A0A165TBH9	ATP-dependent metallopeptidase Hfl. (843 aa)
	A0A165TBM3	GrpE-domain-containing protein. (262 aa)
	A0A165TBQ5	Uncharacterized protein. (243 aa)
	A0A165TC35	ARM repeat-containing protein. (351 aa)
	A0A165TC71	Uncharacterized protein. (352 aa)
	A0A165TF05	GST_C_6 domain-containing protein. (294 aa)
	A0A165TK89	Uncharacterized protein. (233 aa)
	A0A165TNG2	Rhomboid-domain-containing protein. (314 aa)
	A0A165TS64	Sulfhydryl oxidase. (219 aa)
	A0A165TXJ8	Mitochondrial import protein Pam17. (194 aa)
	A0A165TXV9	Uncharacterized protein. (490 aa)
	A0A165TZP8	Uncharacterized protein. (154 aa)
	A0A165U2C9	Lactamase_B domain-containing protein. (368 aa)
	A0A165U4U4	Uncharacterized protein. (865 aa)
	A0A165U6Z1	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (459 aa)
	A0A165U7H4	Tim17-domain-containing protein. (210 aa)
	A0A165UAH4	Uncharacterized protein. (86 aa)
	A0A165UE07	Cytosine-purine permease; Belongs to the purine-cytosine permease (2.A.39) family. (505 aa)
	A0A165UFR5	DnaJ-domain-containing protein. (586 aa)
	A0A165UMU0	Uncharacterized protein; Belongs to the AAA ATPase family. (444 aa)
	A0A165UN31	Uncharacterized protein. (372 aa)
	A0A165URD3	COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (69 aa)
	A0A165V634	Tim17-domain-containing protein. (168 aa)
	A0A165V8L3	MAS20-domain-containing protein. (543 aa)
	A0A165V9M5	Mitochondrial genome maintenance MGM101. (201 aa)
	A0A165VBX6	PHB domain-containing protein. (379 aa)
	A0A165VH06	Carbohydrate esterase family 15 protein. (408 aa)
	A0A165VIP1	MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (663 aa)
	A0A165VN57	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (68 aa)
	A0A165VPF7	J domain-containing protein. (106 aa)
	A0A165VXY8	SMP-LTD domain-containing protein. (342 aa)
	A0A165W1F3	COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (82 aa)
	A0A165W360	PHB domain-containing protein. (315 aa)
	A0A165W3J4	RHOMBOID-like protein. (500 aa)
	A0A165W3T6	ATP-dependent metallopeptidase Hfl. (793 aa)
	A0A165WB57	WLM-domain-containing protein. (347 aa)
	A0A165WCS5	Cytosine-purine permease; Belongs to the purine-cytosine permease (2.A.39) family. (516 aa)

Your Current Organism:

Neolentinus lepideus

NCBI taxonomy Id: 1314782
Other names: N. lepideus HHB14362 ss-1, Neolentinus lepideus HHB14362 ss-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A165MU85	A0A165QRE3	A0A165MU85	A0A165QRE3	Zinc/iron permease.	Bac_surface_Ag domain-containing protein.	0.685
A0A165MU85	A0A165S287	A0A165MU85	A0A165S287	Zinc/iron permease.	Uncharacterized protein.	0.451
A0A165MU85	A0A165TBQ5	A0A165MU85	A0A165TBQ5	Zinc/iron permease.	Uncharacterized protein.	0.453
A0A165MU85	A0A165TC71	A0A165MU85	A0A165TC71	Zinc/iron permease.	Uncharacterized protein.	0.453
A0A165MU85	A0A165TF05	A0A165MU85	A0A165TF05	Zinc/iron permease.	GST_C_6 domain-containing protein.	0.598
A0A165MU85	A0A165UN31	A0A165MU85	A0A165UN31	Zinc/iron permease.	Uncharacterized protein.	0.598
A0A165MU85	A0A165VXY8	A0A165MU85	A0A165VXY8	Zinc/iron permease.	SMP-LTD domain-containing protein.	0.808
A0A165MU85	MDM34	A0A165MU85	A0A165S1T1	Zinc/iron permease.	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	0.489
A0A165NCP8	A0A165NIF7	A0A165NCP8	A0A165NIF7	Mitochondrial import inner membrane translocase subunit TIM9.	Uncharacterized protein.	0.800
A0A165NCP8	A0A165P8T2	A0A165NCP8	A0A165P8T2	Mitochondrial import inner membrane translocase subunit TIM9.	ADP/ATP carrier receptor.	0.498
A0A165NCP8	A0A165PHY1	A0A165NCP8	A0A165PHY1	Mitochondrial import inner membrane translocase subunit TIM9.	Tim17-domain-containing protein.	0.990
A0A165NCP8	A0A165PJB5	A0A165NCP8	A0A165PJB5	Mitochondrial import inner membrane translocase subunit TIM9.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.503
A0A165NCP8	A0A165PLS9	A0A165NCP8	A0A165PLS9	Mitochondrial import inner membrane translocase subunit TIM9.	DDE_3 domain-containing protein.	0.782
A0A165NCP8	A0A165PLT9	A0A165NCP8	A0A165PLT9	Mitochondrial import inner membrane translocase subunit TIM9.	Uncharacterized protein.	0.782
A0A165NCP8	A0A165PQX5	A0A165NCP8	A0A165PQX5	Mitochondrial import inner membrane translocase subunit TIM9.	Uncharacterized protein.	0.501
A0A165NCP8	A0A165PYE8	A0A165NCP8	A0A165PYE8	Mitochondrial import inner membrane translocase subunit TIM9.	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family.	0.917
A0A165NCP8	A0A165PZT3	A0A165NCP8	A0A165PZT3	Mitochondrial import inner membrane translocase subunit TIM9.	zf-Tim10_DDP domain-containing protein.	0.999
A0A165NCP8	A0A165QRE3	A0A165NCP8	A0A165QRE3	Mitochondrial import inner membrane translocase subunit TIM9.	Bac_surface_Ag domain-containing protein.	0.439
A0A165NCP8	A0A165RFR4	A0A165NCP8	A0A165RFR4	Mitochondrial import inner membrane translocase subunit TIM9.	Uncharacterized protein.	0.503
A0A165NCP8	A0A165RHH7	A0A165NCP8	A0A165RHH7	Mitochondrial import inner membrane translocase subunit TIM9.	Uncharacterized protein.	0.518