(36 nodes) Ubiquitin-dependent ERAD pathway network (Neolentinus lepideus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A165N695	UBX domain-containing protein. (242 aa)
	A0A165NJ03	RING-type domain-containing protein. (917 aa)
	A0A165NTH7	DnaJ-domain-containing protein. (436 aa)
	A0A165PFB0	Valosin-containing protein; Belongs to the AAA ATPase family. (814 aa)
	A0A165PL36	RING-CH-type domain-containing protein. (1532 aa)
	A0A165QC64	UV excision repair protein Rad23. (400 aa)
	A0A165QF81	DnaJ-domain-containing protein. (374 aa)
	A0A165QT10	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (222 aa)
	A0A165R7V2	Uncharacterized protein. (444 aa)
	A0A165R801	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (216 aa)
	A0A165RA71	HCP-like protein. (971 aa)
	A0A165RHS2	Polyubiquitin-tagged protein recognition complex Npl4 component. (655 aa)
	A0A165RIL9	TPR-like protein. (210 aa)
	A0A165RJG3	Uncharacterized protein. (446 aa)
	A0A165RYW3	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (870 aa)
	A0A165S0Y9	HSP90-domain-containing protein. (1564 aa)
	A0A165S3T5	HECT-domain-containing protein. (1012 aa)
	A0A165SBZ6	Heat shock protein 70; Belongs to the heat shock protein 70 family. (671 aa)
	A0A165SCD4	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (173 aa)
	A0A165SHP3	UBC-like protein. (258 aa)
	A0A165SIU2	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (626 aa)
	A0A165SN06	U-box domain-containing protein. (1165 aa)
	A0A165SSE6	UBX domain-containing protein. (553 aa)
	A0A165SVJ5	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (547 aa)
	A0A165T883	PRKCSH domain-containing protein. (466 aa)
	A0A165TAU1	UFD1-domain-containing protein. (438 aa)
	A0A165TDK8	OTU-domain-containing protein. (332 aa)
	A0A165TFS2	N-acetyltransferase. (185 aa)
	A0A165U552	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (550 aa)
	A0A165U7C3	bVLRF1 domain-containing protein. (661 aa)
	A0A165UC99	26S proteasome subunit P45; Belongs to the AAA ATPase family. (388 aa)
	A0A165UE22	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (259 aa)
	A0A165UR30	UBC-like protein. (299 aa)
	A0A165V402	Uncharacterized protein. (574 aa)
	A0A165V7C2	Long chronological lifespan protein 2; Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway. (103 aa)
	A0A165V8K6	P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the AAA ATPase family. (493 aa)

Your Current Organism:

Neolentinus lepideus

NCBI taxonomy Id: 1314782
Other names: N. lepideus HHB14362 ss-1, Neolentinus lepideus HHB14362 ss-1

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A165N695	A0A165PFB0	UBX domain-containing protein.	Valosin-containing protein; Belongs to the AAA ATPase family.	0.945
A0A165N695	A0A165RHS2	UBX domain-containing protein.	Polyubiquitin-tagged protein recognition complex Npl4 component.	0.939
A0A165N695	A0A165SSE6	UBX domain-containing protein.	UBX domain-containing protein.	0.972
A0A165N695	A0A165TAU1	UBX domain-containing protein.	UFD1-domain-containing protein.	0.577
A0A165N695	A0A165TDK8	UBX domain-containing protein.	OTU-domain-containing protein.	0.595
A0A165N695	A0A165V8K6	UBX domain-containing protein.	P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the AAA ATPase family.	0.945
A0A165NJ03	A0A165PFB0	RING-type domain-containing protein.	Valosin-containing protein; Belongs to the AAA ATPase family.	0.968
A0A165NJ03	A0A165PL36	RING-type domain-containing protein.	RING-CH-type domain-containing protein.	0.837
A0A165NJ03	A0A165QC64	RING-type domain-containing protein.	UV excision repair protein Rad23.	0.826
A0A165NJ03	A0A165QT10	RING-type domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.577
A0A165NJ03	A0A165R7V2	RING-type domain-containing protein.	Uncharacterized protein.	0.969
A0A165NJ03	A0A165R801	RING-type domain-containing protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.969
A0A165NJ03	A0A165RA71	RING-type domain-containing protein.	HCP-like protein.	0.995
A0A165NJ03	A0A165RHS2	RING-type domain-containing protein.	Polyubiquitin-tagged protein recognition complex Npl4 component.	0.811
A0A165NJ03	A0A165RJG3	RING-type domain-containing protein.	Uncharacterized protein.	0.958
A0A165NJ03	A0A165RYW3	RING-type domain-containing protein.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.536
A0A165NJ03	A0A165S0Y9	RING-type domain-containing protein.	HSP90-domain-containing protein.	0.489
A0A165NJ03	A0A165SBZ6	RING-type domain-containing protein.	Heat shock protein 70; Belongs to the heat shock protein 70 family.	0.784
A0A165NJ03	A0A165SCD4	RING-type domain-containing protein.	Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.955
A0A165NJ03	A0A165SHP3	RING-type domain-containing protein.	UBC-like protein.	0.470