(17 nodes) Autophagy of nucleus network (Neolentinus lepideus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A165LT96	Alpha/beta-hydrolase. (276 aa)
	A0A165MCC7	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (355 aa)
	A0A165MW02	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (672 aa)
	A0A165MXX2	Alpha/beta-hydrolase. (416 aa)
	A0A165MYC7	WD40 repeat-like protein. (372 aa)
	A0A165PYS3	PH domain-containing protein. (764 aa)
	A0A165RVH2	Uncharacterized protein; Belongs to the OSBP family. (1148 aa)
	A0A165S503	Oxysterol-binding protein; Belongs to the OSBP family. (401 aa)
	A0A165T1H2	Kinase-like protein. (859 aa)
	A0A165TCP2	Uncharacterized protein. (2342 aa)
	A0A165TED8	Alpha/beta-hydrolase. (420 aa)
	A0A165TX20	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (958 aa)
	A0A165V4D0	Uncharacterized protein. (376 aa)
	A0A165VLS8	Alpha beta-hydrolase. (289 aa)
	A0A165NB24	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (125 aa)
	A0A165PBX9	WD40 repeat-like protein. (454 aa)
	A0A165PS31	Autophagy-related protein 3. (373 aa)

Your Current Organism:

Neolentinus lepideus

NCBI taxonomy Id: 1314782
Other names: N. lepideus HHB14362 ss-1, Neolentinus lepideus HHB14362 ss-1

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A165LT96	A0A165MCC7	Alpha/beta-hydrolase.	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	0.822
A0A165LT96	A0A165MW02	Alpha/beta-hydrolase.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.825
A0A165LT96	A0A165MYC7	Alpha/beta-hydrolase.	WD40 repeat-like protein.	0.819
A0A165LT96	A0A165NB24	Alpha/beta-hydrolase.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	0.826
A0A165LT96	A0A165PS31	Alpha/beta-hydrolase.	Autophagy-related protein 3.	0.706
A0A165LT96	A0A165T1H2	Alpha/beta-hydrolase.	Kinase-like protein.	0.832
A0A165LT96	A0A165TCP2	Alpha/beta-hydrolase.	Uncharacterized protein.	0.815
A0A165LT96	A0A165TED8	Alpha/beta-hydrolase.	Alpha/beta-hydrolase.	0.590
A0A165LT96	A0A165V4D0	Alpha/beta-hydrolase.	Uncharacterized protein.	0.706
A0A165MCC7	A0A165LT96	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Alpha/beta-hydrolase.	0.822
A0A165MCC7	A0A165MW02	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.901
A0A165MCC7	A0A165MXX2	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Alpha/beta-hydrolase.	0.822
A0A165MCC7	A0A165MYC7	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	WD40 repeat-like protein.	0.958
A0A165MCC7	A0A165NB24	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	0.999
A0A165MCC7	A0A165PBX9	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	WD40 repeat-like protein.	0.502
A0A165MCC7	A0A165PS31	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Autophagy-related protein 3.	0.987
A0A165MCC7	A0A165T1H2	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Kinase-like protein.	0.969
A0A165MCC7	A0A165TCP2	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Uncharacterized protein.	0.534
A0A165MCC7	A0A165TED8	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Alpha/beta-hydrolase.	0.822
A0A165MCC7	A0A165TX20	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.628