(76 nodes) Glycolysis / Gluconeogenesis network (Neolentinus lepideus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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	A0A165V7L3	Homoserine acetyltransferase. (508 aa)
	A0A165MM50	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (288 aa)
	A0A165MRV9	Cofactor-independent phosphoglycerate mutase. (518 aa)
	A0A165MUG5	Dihydrolipoyl dehydrogenase. (497 aa)
	A0A165MXS3	GroES-like protein. (355 aa)
	A0A165N2X5	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (288 aa)
	A0A165N7K1	Galactose mutarotase-like protein. (374 aa)
	A0A165NBI8	2R-phospho-3-sulfolactate synthase. (316 aa)
	A0A165NDV1	Pyruvate decarboxylase. (600 aa)
	A0A165NUV1	TPR-like protein. (374 aa)
	A0A165NXK4	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (416 aa)
	A0A165P136	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (342 aa)
	A0A165P1N8	Uncharacterized protein. (130 aa)
	A0A165P8P3	Maleylacetate reductase. (361 aa)
	A0A165P9N8	Uncharacterized protein. (170 aa)
	A0A165PBA8	Uncharacterized protein. (415 aa)
	A0A165PD02	Glucose-6-phosphate isomerase; Belongs to the GPI family. (552 aa)
	A0A165PKL3	Alcohol dehydogenase. (340 aa)
	A0A165PX85	Phosphoglucomutase; Belongs to the phosphohexose mutase family. (566 aa)
	A0A165Q0L3	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa)
	A0A165QE46	NAD-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (536 aa)
	A0A165QFA7	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (801 aa)
	A0A165QXP6	Glyceraldehyde-3-phosphate dehydrogenase. (336 aa)
	A0A165R0Z8	Galactose mutarotase-like protein. (428 aa)
	A0A165R8H1	Aldolase. (387 aa)
	A0A165RLZ4	GroES-like protein. (358 aa)
	A0A165RPR7	Pyruvate dehydrogenase X component. (305 aa)
	A0A165RQK3	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa)
	A0A165RTQ9	ATP-utilizing phosphoenolpyruvate carboxykinase. (614 aa)
	A0A165RVE0	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (502 aa)
	A0A165RZ68	NAD-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (503 aa)
	A0A165S0H7	Dehydroquinate synthase-like protein. (491 aa)
	A0A165S9N0	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (511 aa)
	A0A165SMZ4	Phosphoglycerate mutase-like protein. (289 aa)
	A0A165SNU9	Aldedh domain-containing protein. (496 aa)
	A0A165SNY3	Galactose mutarotase-like protein. (167 aa)
	A0A165SNZ0	Uncharacterized protein. (82 aa)
	A0A165SW41	GroES-like protein. (359 aa)
	A0A165SX07	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa)
	A0A165SYC8	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (476 aa)
	A0A165T0H5	Triosephosphate isomerase. (251 aa)
	A0A165T2B6	Phosphotransferase. (500 aa)
	A0A165T4S8	Acetyl-coenzyme A synthetase. (672 aa)
	A0A165T9J9	Phosphoglucomutase, first 3 domain-containing protein. (605 aa)
	A0A165TBS4	Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family. (338 aa)
	A0A165TFZ1	Phosphoglycerate mutase-like protein. (218 aa)
	A0A165TK37	Alcohol dehydrogenase IV. (383 aa)
	A0A165TK61	Alcohol dehydrogenase IV. (397 aa)
	A0A165TMB0	Phosphotransferase. (558 aa)
	A0A165TQ01	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (381 aa)
	A0A165TUX1	Aldedh-domain-containing protein; Belongs to the aldehyde dehydrogenase family. (614 aa)
	A0A165TWQ0	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
	A0A165U4T5	Phosphopyruvate hydratase. (444 aa)
	A0A165UE54	GroES-like protein. (363 aa)
	A0A165UG27	Fructose-bisphosphate aldolase class-I. (361 aa)
	A0A165V3H9	Ribosome biogenesis protein tsr1. (796 aa)
	A0A165V7L9	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (531 aa)
	A0A165V7P4	GroES-like protein. (340 aa)
	A0A165V7S0	GroES-like protein. (295 aa)
	A0A165V8J2	Cleft lip and palate associated transmembrane protein. (627 aa)
	A0A165V8J9	Uncharacterized protein. (850 aa)
	A0A165V926	GroES-like protein. (341 aa)
	A0A165V9J1	Uncharacterized protein. (693 aa)
	A0A165VH39	Alcohol dehydrogenase GroES domain protein. (373 aa)
	A0A165VH50	Alcohol dehydrogenase GroES domain protein. (373 aa)
	A0A165VHD8	Alcohol dehydrogenase GroES domain protein. (373 aa)
	TRM8	tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (262 aa)
	A0A165VUF7	Phosphatase activator. (326 aa)
	A0A165VY15	NADPH-dependent alcohol dehydrogenase. (380 aa)
	A0A165VY22	NADPH-dependent alcohol dehydrogenase. (353 aa)
	A0A165VY25	NADPH-dependent alcohol dehydrogenase. (357 aa)
	A0A165VYG8	Glucose-6-phosphate 1-epimerase; Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P). (306 aa)
	A0A165W1A4	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (436 aa)
	A0A165W3B9	Pyruvate kinase; Belongs to the pyruvate kinase family. (535 aa)
	A0A165W4U7	WD repeat-containing protein 8. (481 aa)
	A0A165W5E5	Phosphoglycerate mutase-like protein. (221 aa)

Your Current Organism:

Neolentinus lepideus

NCBI taxonomy Id: 1314782
Other names: N. lepideus HHB14362 ss-1, Neolentinus lepideus HHB14362 ss-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A165MM50	A0A165MRV9	A0A165MM50	A0A165MRV9	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Cofactor-independent phosphoglycerate mutase.	0.853
A0A165MM50	A0A165MUG5	A0A165MM50	A0A165MUG5	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Dihydrolipoyl dehydrogenase.	0.419
A0A165MM50	A0A165N2X5	A0A165MM50	A0A165N2X5	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	0.731
A0A165MM50	A0A165N7K1	A0A165MM50	A0A165N7K1	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Galactose mutarotase-like protein.	0.460
A0A165MM50	A0A165NDV1	A0A165MM50	A0A165NDV1	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Pyruvate decarboxylase.	0.910
A0A165MM50	A0A165NUV1	A0A165MM50	A0A165NUV1	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	TPR-like protein.	0.958
A0A165MM50	A0A165NXK4	A0A165MM50	A0A165NXK4	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.	0.973
A0A165MM50	A0A165P136	A0A165MM50	A0A165P136	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.869
A0A165MM50	A0A165P9N8	A0A165MM50	A0A165P9N8	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Uncharacterized protein.	0.814
A0A165MM50	A0A165PD02	A0A165MM50	A0A165PD02	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.975
A0A165MM50	A0A165PX85	A0A165MM50	A0A165PX85	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Phosphoglucomutase; Belongs to the phosphohexose mutase family.	0.853
A0A165MM50	A0A165Q0L3	A0A165MM50	A0A165Q0L3	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.766
A0A165MM50	A0A165QE46	A0A165MM50	A0A165QE46	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	NAD-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.734
A0A165MM50	A0A165QFA7	A0A165MM50	A0A165QFA7	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.925
A0A165MM50	A0A165QXP6	A0A165MM50	A0A165QXP6	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.979
A0A165MM50	A0A165R0Z8	A0A165MM50	A0A165R0Z8	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Galactose mutarotase-like protein.	0.460
A0A165MM50	A0A165R8H1	A0A165MM50	A0A165R8H1	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Aldolase.	0.846
A0A165MM50	A0A165RPR7	A0A165MM50	A0A165RPR7	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Pyruvate dehydrogenase X component.	0.799
A0A165MM50	A0A165RQK3	A0A165MM50	A0A165RQK3	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.814
A0A165MM50	A0A165RVE0	A0A165MM50	A0A165RVE0	Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.766