(105 nodes) Lysine degradation network (Neolentinus lepideus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A165W972	Uncharacterized protein. (275 aa)
	A0A165VWQ9	AlaDh_PNT_N domain-containing protein. (995 aa)
	A0A165VSN5	Uncharacterized protein. (865 aa)
	A0A165VRR4	DUF2470 domain-containing protein. (217 aa)
	A0A165VMK6	MYND-type domain-containing protein. (203 aa)
	A0A165VH19	Trimethyllysine dioxygenase. (476 aa)
	A0A165VA99	Succinate-semialdehyde dehydrogenase. (492 aa)
	A0A165V7L9	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (531 aa)
	A0A165V7L3	Homoserine acetyltransferase. (508 aa)
	A0A165V3H4	MYND-type domain-containing protein. (236 aa)
	A0A165V2R8	Uncharacterized protein. (413 aa)
	A0A165V208	Uncharacterized protein. (914 aa)
	A0A165V0M3	PHD domain-containing protein. (673 aa)
	A0A165UZN3	SET domain-containing protein. (379 aa)
	A0A165UYA4	SET domain-containing protein. (366 aa)
	A0A165UML2	Uncharacterized protein. (722 aa)
	A0A165UFP2	Uncharacterized protein. (122 aa)
	A0A165UFM2	Uncharacterized protein. (74 aa)
	A0A165U523	Uncharacterized protein. (100 aa)
	A0A165TZD6	Uncharacterized protein. (342 aa)
	A0A165TUX1	Aldedh-domain-containing protein; Belongs to the aldehyde dehydrogenase family. (614 aa)
	A0A165TKL6	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
	A0A165TDD9	Kinase-like protein. (871 aa)
	A0A165T833	Rab-GAP TBC domain-containing protein. (1302 aa)
	A0A165T247	Fructosyl amino acid oxidase. (452 aa)
	A0A165T0F2	SET domain-containing protein. (373 aa)
	A0A165SYC8	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (476 aa)
	A0A165NFC1	Uncharacterized protein. (636 aa)
	A0A165NF46	Uncharacterized protein. (62 aa)
	A0A165NES6	Uncharacterized protein. (115 aa)
	A0A165NAW5	SET domain-containing protein. (187 aa)
	A0A165N1S0	SET domain-containing protein. (662 aa)
	A0A165MZU7	Uncharacterized protein. (324 aa)
	A0A165MZN7	Uncharacterized protein. (201 aa)
	A0A165MZE6	Uncharacterized protein. (198 aa)
	A0A165MYE9	CXC domain-containing protein. (557 aa)
	A0A165MY96	SET domain-containing protein. (518 aa)
	A0A165MWU3	Uncharacterized protein. (276 aa)
	A0A165MUG5	Dihydrolipoyl dehydrogenase. (497 aa)
	A0A165MSK4	MYND-type domain-containing protein. (93 aa)
	A0A165MRS0	Uncharacterized protein. (345 aa)
	A0A165MEH9	Uncharacterized protein. (252 aa)
	A0A165MEC4	Uncharacterized protein. (181 aa)
	A0A165SNU9	Aldedh domain-containing protein. (496 aa)
	A0A165SG74	Uncharacterized protein. (115 aa)
	A0A165SG27	Uncharacterized protein. (59 aa)
	A0A165SDB3	Uncharacterized protein. (344 aa)
	A0A165SCX9	MYND-type domain-containing protein. (502 aa)
	A0A165SCU0	Uncharacterized protein. (139 aa)
	A0A165SCT2	Uncharacterized protein. (468 aa)
	A0A165SCL8	Uncharacterized protein. (205 aa)
	A0A165SC30	Uncharacterized protein. (350 aa)
	A0A165SB15	SET domain-containing protein. (662 aa)
	A0A165SAQ5	Dihydrolipoamide succinyltransferase. (450 aa)
	A0A165S9N0	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (511 aa)
	A0A165S913	Dehydrogenase E1 and transketolase domain-containing protein 1. (939 aa)
	A0A165S571	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (537 aa)
	A0A165S486	Uncharacterized protein. (346 aa)
	A0A165RZ68	NAD-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (503 aa)
	A0A165RZ16	Uncharacterized protein. (528 aa)
	A0A165RYT1	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa)
	A0A165RWD0	SET domain-containing protein. (478 aa)
	A0A165RVE0	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (502 aa)
	A0A165RQK3	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa)
	A0A165RJS1	MYND-type domain-containing protein. (605 aa)
	A0A165RJN8	MYND-type domain-containing protein. (523 aa)
	A0A165RCB8	UPF0075-domain-containing protein. (439 aa)
	A0A165RAZ4	FAD dependent oxidoreductase. (428 aa)
	A0A165R7V5	SET domain-containing protein. (440 aa)
	A0A165QZT1	F-box domain-containing protein. (515 aa)
	A0A165QXI4	SET domain-containing protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (819 aa)
	A0A165QPB7	Uncharacterized protein. (225 aa)
	A0A165QNZ5	Uncharacterized protein. (319 aa)
	A0A165QNU0	Uncharacterized protein. (362 aa)
	A0A165QH98	Isochorismatase hydrolase. (212 aa)
	A0A165QE46	NAD-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (536 aa)
	A0A165NL25	Uncharacterized protein. (318 aa)
	A0A165NL96	Uncharacterized protein. (89 aa)
	A0A165NLQ2	PHD-type domain-containing protein. (1557 aa)
	A0A165NS03	Uncharacterized protein. (182 aa)
	A0A165NVM8	Uncharacterized protein. (269 aa)
	A0A165NWQ9	Saccharopine dehydrogenase; Belongs to the spermidine/spermine synthase family. (751 aa)
	A0A165NX19	Zn(2)-C6 fungal-type domain-containing protein. (379 aa)
	A0A165P086	Zn(2)-C6 fungal-type domain-containing protein. (849 aa)
	A0A165P1H0	Uncharacterized protein. (393 aa)
	A0A165PEE7	SET domain-containing protein. (619 aa)
	A0A165PJ99	Uncharacterized protein. (398 aa)
	A0A165PJD9	FAD dependent oxidoreductase. (437 aa)
	A0A165PPA0	SET domain-containing protein. (425 aa)
	A0A165PS01	MYND-type domain-containing protein. (299 aa)
	A0A165PSC4	Uncharacterized protein. (371 aa)
	A0A165PSD7	Uncharacterized protein. (261 aa)
	A0A165PTR1	Acyl-CoA dehydrogenase NM domain-like protein. (358 aa)
	A0A165PTY5	Acyl-CoA dehydrogenase NM domain-like protein. (222 aa)
	A0A165PTZ6	Acyl-CoA_dh_N domain-containing protein. (143 aa)
	A0A165PUI7	Acyl-CoA dehydrogenase NM domain-like protein. (240 aa)
	A0A165PUY2	Acyl-CoA dehydrogenase/oxidase C-terminal. (242 aa)
	A0A165PYC9	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (368 aa)
	A0A165Q0L3	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa)
	A0A165Q1V5	Clavaminate synthase-like protein. (197 aa)
	A0A165QBE3	Uncharacterized protein. (261 aa)
	A0A165QE35	Uncharacterized protein. (1418 aa)
	A0A165WC22	DAO-domain-containing protein. (486 aa)
	A0A165WAY9	BSP-domain-containing protein. (615 aa)
	A0A165W9W7	Thioredoxin-domain-containing protein. (164 aa)

Your Current Organism:

Neolentinus lepideus

NCBI taxonomy Id: 1314782
Other names: N. lepideus HHB14362 ss-1, Neolentinus lepideus HHB14362 ss-1

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A165MEC4	A0A165S571	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.469
A0A165MEH9	A0A165S571	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.469
A0A165MRS0	A0A165QXI4	Uncharacterized protein.	SET domain-containing protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.431
A0A165MSK4	A0A165S571	MYND-type domain-containing protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.425
A0A165MUG5	A0A165PJD9	Dihydrolipoyl dehydrogenase.	FAD dependent oxidoreductase.	0.569
A0A165MUG5	A0A165PTR1	Dihydrolipoyl dehydrogenase.	Acyl-CoA dehydrogenase NM domain-like protein.	0.708
A0A165MUG5	A0A165PTY5	Dihydrolipoyl dehydrogenase.	Acyl-CoA dehydrogenase NM domain-like protein.	0.708
A0A165MUG5	A0A165PTZ6	Dihydrolipoyl dehydrogenase.	Acyl-CoA_dh_N domain-containing protein.	0.556
A0A165MUG5	A0A165PUI7	Dihydrolipoyl dehydrogenase.	Acyl-CoA dehydrogenase NM domain-like protein.	0.708
A0A165MUG5	A0A165PUY2	Dihydrolipoyl dehydrogenase.	Acyl-CoA dehydrogenase/oxidase C-terminal.	0.708
A0A165MUG5	A0A165QH98	Dihydrolipoyl dehydrogenase.	Isochorismatase hydrolase.	0.993
A0A165MUG5	A0A165RAZ4	Dihydrolipoyl dehydrogenase.	FAD dependent oxidoreductase.	0.569
A0A165MUG5	A0A165RQK3	Dihydrolipoyl dehydrogenase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.421
A0A165MUG5	A0A165S913	Dihydrolipoyl dehydrogenase.	Dehydrogenase E1 and transketolase domain-containing protein 1.	0.983
A0A165MUG5	A0A165S9N0	Dihydrolipoyl dehydrogenase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.421
A0A165MUG5	A0A165SAQ5	Dihydrolipoyl dehydrogenase.	Dihydrolipoamide succinyltransferase.	0.997
A0A165MUG5	A0A165SNU9	Dihydrolipoyl dehydrogenase.	Aldedh domain-containing protein.	0.421
A0A165MUG5	A0A165T247	Dihydrolipoyl dehydrogenase.	Fructosyl amino acid oxidase.	0.567
A0A165MUG5	A0A165VA99	Dihydrolipoyl dehydrogenase.	Succinate-semialdehyde dehydrogenase.	0.780
A0A165MUG5	A0A165VH19	Dihydrolipoyl dehydrogenase.	Trimethyllysine dioxygenase.	0.421