(31 nodes) Butanoate metabolism network (Neolentinus lepideus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	A0A165MI19	PLP-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (430 aa)
	A0A165MZE6	Uncharacterized protein. (198 aa)
	A0A165MZN7	Uncharacterized protein. (201 aa)
	A0A165MZU7	Uncharacterized protein. (324 aa)
	A0A165NJB2	Acetolactate synthase. (343 aa)
	A0A165NVM8	Uncharacterized protein. (269 aa)
	A0A165P1X0	Asp/Glu racemase. (405 aa)
	A0A165P9S0	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (474 aa)
	A0A165PJ99	Uncharacterized protein. (398 aa)
	A0A165PSC4	Uncharacterized protein. (371 aa)
	A0A165S043	Acetoacetyl-CoA synthetase. (711 aa)
	A0A165W972	Uncharacterized protein. (275 aa)
	A0A165VA99	Succinate-semialdehyde dehydrogenase. (492 aa)
	A0A165V0Y8	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (508 aa)
	A0A165URJ9	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (454 aa)
	A0A165UNX4	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (513 aa)
	A0A165UNW8	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (524 aa)
	A0A165TQK3	NAD dehydrogenase. (456 aa)
	A0A165TKL6	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
	A0A165SEJ3	Uncharacterized protein. (363 aa)
	A0A165PSD7	Uncharacterized protein. (261 aa)
	A0A165PWS9	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (480 aa)
	A0A165QBE3	Uncharacterized protein. (261 aa)
	A0A165S5X8	DAO-domain-containing protein. (526 aa)
	A0A165QJQ5	Uncharacterized protein. (306 aa)
	A0A165QLC7	Acetoacetate-CoA ligase. (681 aa)
	A0A165QVB2	Aldolase. (360 aa)
	A0A165QXT4	DAO-domain-containing protein. (491 aa)
	A0A165R1K3	Putative transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (468 aa)
	A0A165RL88	Acetolactate synthase. (592 aa)
	A0A165RYT1	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa)

Your Current Organism:

Neolentinus lepideus

NCBI taxonomy Id: 1314782
Other names: N. lepideus HHB14362 ss-1, Neolentinus lepideus HHB14362 ss-1

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A165MI19	A0A165NJB2	PLP-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Acetolactate synthase.	0.483
A0A165MI19	A0A165P9S0	PLP-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.517
A0A165MI19	A0A165QJQ5	PLP-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Uncharacterized protein.	0.595
A0A165MI19	A0A165TKL6	PLP-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.430
A0A165MI19	A0A165URJ9	PLP-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.681
A0A165MI19	A0A165VA99	PLP-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Succinate-semialdehyde dehydrogenase.	0.690
A0A165MZE6	A0A165PWS9	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.933
A0A165MZE6	A0A165QJQ5	Uncharacterized protein.	Uncharacterized protein.	0.872
A0A165MZE6	A0A165QLC7	Uncharacterized protein.	Acetoacetate-CoA ligase.	0.568
A0A165MZE6	A0A165QVB2	Uncharacterized protein.	Aldolase.	0.522
A0A165MZE6	A0A165S043	Uncharacterized protein.	Acetoacetyl-CoA synthetase.	0.568
A0A165MZE6	A0A165SEJ3	Uncharacterized protein.	Uncharacterized protein.	0.871
A0A165MZE6	A0A165TKL6	Uncharacterized protein.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.796
A0A165MZE6	A0A165UNW8	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.601
A0A165MZE6	A0A165UNX4	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.601
A0A165MZN7	A0A165PWS9	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.933
A0A165MZN7	A0A165QJQ5	Uncharacterized protein.	Uncharacterized protein.	0.872
A0A165MZN7	A0A165QLC7	Uncharacterized protein.	Acetoacetate-CoA ligase.	0.568
A0A165MZN7	A0A165QVB2	Uncharacterized protein.	Aldolase.	0.522
A0A165MZN7	A0A165S043	Uncharacterized protein.	Acetoacetyl-CoA synthetase.	0.568