(25 nodes) Autophagy - other network (Neolentinus lepideus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	A0A165VLD9	Uncharacterized protein. (170 aa)
	A0A165MCC7	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (355 aa)
	A0A165MRR5	DUF1649-domain-containing protein. (181 aa)
	A0A165MW02	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (672 aa)
	A0A165MYC7	WD40 repeat-like protein. (372 aa)
	A0A165NB24	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (125 aa)
	A0A165PS31	Autophagy-related protein 3. (373 aa)
	A0A165PYY3	ATG16-domain-containing protein. (263 aa)
	A0A165Q7P5	Serine/threonine-protein phosphatase. (306 aa)
	A0A165QEL0	WD40 repeat-like protein. (1663 aa)
	A0A165RDW5	ATG11 domain-containing protein. (1332 aa)
	A0A165RUL8	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (925 aa)
	A0A165RYU2	Autophagy_act_C domain-containing protein. (223 aa)
	A0A165T0A9	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (743 aa)
	A0A165T1H2	Kinase-like protein. (859 aa)
	A0A165TCP2	Uncharacterized protein. (2342 aa)
	A0A165TX20	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (958 aa)
	A0A165TXD3	TAP42-like protein. (387 aa)
	A0A165U149	WD40 repeat-like protein. (1435 aa)
	A0A165UBZ6	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2361 aa)
	A0A165UPD9	WD40 repeat-like protein. (329 aa)
	A0A165URM3	Autophagy-related protein. (124 aa)
	A0A165V1J3	APG6-domain-containing protein. (487 aa)
	A0A165V4D0	Uncharacterized protein. (376 aa)
	A0A165VH74	Phosphatidylinositol 3-kinase VPS34. (843 aa)

Your Current Organism:

Neolentinus lepideus

NCBI taxonomy Id: 1314782
Other names: N. lepideus HHB14362 ss-1, Neolentinus lepideus HHB14362 ss-1

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A165MCC7	A0A165MRR5	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	DUF1649-domain-containing protein.	0.582
A0A165MCC7	A0A165MW02	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.901
A0A165MCC7	A0A165MYC7	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	WD40 repeat-like protein.	0.958
A0A165MCC7	A0A165NB24	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	0.999
A0A165MCC7	A0A165PS31	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Autophagy-related protein 3.	0.987
A0A165MCC7	A0A165PYY3	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	ATG16-domain-containing protein.	0.996
A0A165MCC7	A0A165QEL0	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	WD40 repeat-like protein.	0.833
A0A165MCC7	A0A165RDW5	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	ATG11 domain-containing protein.	0.502
A0A165MCC7	A0A165RUL8	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.	0.592
A0A165MCC7	A0A165T0A9	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily.	0.585
A0A165MCC7	A0A165T1H2	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Kinase-like protein.	0.969
A0A165MCC7	A0A165TCP2	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Uncharacterized protein.	0.534
A0A165MCC7	A0A165TX20	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.628
A0A165MCC7	A0A165UBZ6	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.478
A0A165MCC7	A0A165URM3	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Autophagy-related protein.	0.936
A0A165MCC7	A0A165V1J3	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	APG6-domain-containing protein.	0.833
A0A165MCC7	A0A165V4D0	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Uncharacterized protein.	0.970
A0A165MCC7	A0A165VH74	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	Phosphatidylinositol 3-kinase VPS34.	0.853
A0A165MRR5	A0A165MCC7	DUF1649-domain-containing protein.	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	0.582
A0A165MRR5	A0A165MW02	DUF1649-domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.535