(96 nodes) Histone modification network (Rhizopogon vinicolor)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1B7MMQ5	Uncharacterized protein. (164 aa)
	A0A1B7MLZ7	Uncharacterized protein. (470 aa)
	A0A1B7MLD6	HDAC_interact domain-containing protein. (1198 aa)
	A0A1B7ME58	WD_REPEATS_REGION domain-containing protein. (333 aa)
	A0A1B7MIA4	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (554 aa)
	A0A1B7MIU3	F-box domain-containing protein. (237 aa)
	A0A1B7MKK9	Bromo domain-containing protein. (818 aa)
	A0A1B7ML84	Anti-silencing protein. (188 aa)
	A0A1B7MMQ6	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (153 aa)
	A0A1B7MNC9	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	A0A1B7MP24	WD40 repeat-like protein. (438 aa)
	A0A1B7MPJ1	TPR-like protein. (1088 aa)
	A0A1B7MQ15	Uncharacterized protein. (447 aa)
	A0A1B7MQ35	Uncharacterized protein. (524 aa)
	A0A1B7MQ49	Uncharacterized protein. (224 aa)
	A0A1B7MR96	WD40 repeat-like protein. (416 aa)
	A0A1B7MSU4	WD40 repeat-like protein. (324 aa)
	A0A1B7MT52	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (477 aa)
	A0A1B7MTI7	Fibrillarin. (272 aa)
	A0A1B7MTV9	N-acetyltransferase domain-containing protein. (365 aa)
	A0A1B7MV97	TPR_REGION domain-containing protein. (1116 aa)
	A0A1B7MYQ1	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (804 aa)
	A0A1B7MZ61	HTH myb-type domain-containing protein. (448 aa)
	A0A1B7MZE9	WD40 repeat-like protein. (408 aa)
	A0A1B7MZG4	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1681 aa)
	A0A1B7MZH6	Kinase-like protein. (743 aa)
	A0A1B7MZL1	Uncharacterized protein. (1047 aa)
	A0A1B7MZW9	SET domain-containing protein. (463 aa)
	A0A1B7MZY7	Ubiquitin carboxyl-terminal hydrolase. (587 aa)
	A0A1B7N0L4	WD40 repeat-like protein. (550 aa)
	A0A1B7N135	TFIID-18kDa-domain-containing protein. (331 aa)
	A0A1B7N245	SET domain-containing protein. (544 aa)
	A0A1B7N278	Leo1-domain-containing protein. (538 aa)
	A0A1B7N2T9	Clavaminate synthase-like protein. (973 aa)
	A0A1B7N2V4	B30.2/SPRY domain-containing protein. (647 aa)
	A0A1B7N319	COMPASS complex protein. (450 aa)
	A0A1B7N3L9	RNA polymerase II-associated protein. (422 aa)
	A0A1B7N3T1	Histone deacetylase. (529 aa)
	A0A1B7N3Z1	Uncharacterized protein. (350 aa)
	A0A1B7N474	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa)
	A0A1B7N4C2	Uncharacterized protein. (277 aa)
	A0A1B7N4L9	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (182 aa)
	A0A1B7N4N6	Uncharacterized protein. (317 aa)
	A0A1B7N587	Uncharacterized protein. (673 aa)
	A0A1B7N595	Uncharacterized protein. (665 aa)
	A0A1B7N5G5	E3 ubiquitin protein ligase. (412 aa)
	A0A1B7N659	Uncharacterized protein. (925 aa)
	A0A1B7N667	WD_REPEATS_REGION domain-containing protein. (343 aa)
	A0A1B7N671	Clavaminate synthase-like protein. (442 aa)
	A0A1B7N684	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (545 aa)
	A0A1B7N6G1	SET domain-containing protein. (523 aa)
	A0A1B7N6K6	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (499 aa)
	A0A1B7N6R7	SET domain-containing protein. (557 aa)
	A0A1B7N714	Brg1-associated factor b; Belongs to the actin family. (436 aa)
	A0A1B7N7A2	Kinase-like protein; Belongs to the protein kinase superfamily. (401 aa)
	A0A1B7N7S7	RBR-type E3 ubiquitin transferase. (544 aa)
	A0A1B7N7T9	HDAC_interact domain-containing protein. (1232 aa)
	A0A1B7N7Z7	SET domain-containing protein. (428 aa)
	A0A1B7N835	Uncharacterized protein. (316 aa)
	A0A1B7N856	FAS1 domain-containing protein. (179 aa)
	A0A1B7N8L0	Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. (661 aa)
	A0A1B7N8V0	Uncharacterized protein. (416 aa)
	A0A1B7N9J6	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (3044 aa)
	A0A1B7N9R0	PHD-type domain-containing protein. (851 aa)
	A0A1B7N9V5	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (427 aa)
	A0A1B7N9Y4	Uncharacterized protein. (974 aa)
	A0A1B7NA84	MRG-domain-containing protein. (316 aa)
	SUS1	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...] (96 aa)
	A0A1B7NB26	WD40 repeat-like protein. (484 aa)
	A0A1B7NB34	Thioredoxin-like_fold domain-containing protein. (205 aa)
	A0A1B7NBC3	Chromatin modification-related protein. (465 aa)
	A0A1B7NBW5	PHD-type domain-containing protein. (369 aa)
	A0A1B7NBY0	Acyl-CoA N-acyltransferase. (214 aa)
	A0A1B7NCQ8	DHS-like NAD/FAD-binding domain-containing protein. (513 aa)
	A0A1B7NDE7	NuA4-domain-containing protein. (190 aa)
	A0A1B7NDF9	TFIID-31kDa-domain-containing protein. (262 aa)
	A0A1B7NEA9	Yeats-domain-containing protein. (267 aa)
	A0A1B7NED0	DHS-like NAD/FAD-binding domain-containing protein. (577 aa)
	A0A1B7NEP7	Histone deacetylase clr3. (660 aa)
	A0A1B7NEW9	Bromodomain-domain-containing protein. (516 aa)
	A0A1B7NEZ0	SET domain-containing protein. (598 aa)
	A0A1B7NF14	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3564 aa)
	A0A1B7NFX8	Uncharacterized protein. (420 aa)
	A0A1B7NG59	HSA domain-containing protein. (1245 aa)
	A0A1B7NGH0	Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
	A0A1B7NGK1	Uncharacterized protein. (753 aa)
	A0A1B7NGR5	Uncharacterized protein. (135 aa)
	A0A1B7NGS7	Bromodomain-containing protein. (416 aa)
	A0A1B7NGU5	SET domain-containing protein. (1139 aa)
	A0A1B7NGX5	Uncharacterized protein. (769 aa)
	A0A1B7NH54	WD40 repeat-like protein. (510 aa)
	A0A1B7NHB5	DUF1714 domain-containing protein. (517 aa)
	A0A1B7NHK3	SGF29 C-terminal domain-containing protein. (335 aa)
	A0A1B7NHR9	Myb-like domain-containing protein. (501 aa)
	A0A1B7NI68	TAF1 transcription initiation factor TFIID subunit TAF1. (1042 aa)
	A0A1B7NJ25	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (530 aa)

Your Current Organism:

Rhizopogon vinicolor

NCBI taxonomy Id: 1314800
Other names: R. vinicolor AM-OR11-026, Rhizopogon vinicolor AM-OR11-026

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1B7ME58	A0A1B7MKK9	A0A1B7ME58	A0A1B7MKK9	WD_REPEATS_REGION domain-containing protein.	Bromo domain-containing protein.	0.612
A0A1B7ME58	A0A1B7MLD6	A0A1B7ME58	A0A1B7MLD6	WD_REPEATS_REGION domain-containing protein.	HDAC_interact domain-containing protein.	0.586
A0A1B7ME58	A0A1B7MNC9	A0A1B7ME58	A0A1B7MNC9	WD_REPEATS_REGION domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.493
A0A1B7ME58	A0A1B7MPJ1	A0A1B7ME58	A0A1B7MPJ1	WD_REPEATS_REGION domain-containing protein.	TPR-like protein.	0.630
A0A1B7ME58	A0A1B7MYQ1	A0A1B7ME58	A0A1B7MYQ1	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.488
A0A1B7ME58	A0A1B7MZE9	A0A1B7ME58	A0A1B7MZE9	WD_REPEATS_REGION domain-containing protein.	WD40 repeat-like protein.	0.696
A0A1B7ME58	A0A1B7MZH6	A0A1B7ME58	A0A1B7MZH6	WD_REPEATS_REGION domain-containing protein.	Kinase-like protein.	0.661
A0A1B7ME58	A0A1B7MZY7	A0A1B7ME58	A0A1B7MZY7	WD_REPEATS_REGION domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase.	0.785
A0A1B7ME58	A0A1B7N135	A0A1B7ME58	A0A1B7N135	WD_REPEATS_REGION domain-containing protein.	TFIID-18kDa-domain-containing protein.	0.738
A0A1B7ME58	A0A1B7N319	A0A1B7ME58	A0A1B7N319	WD_REPEATS_REGION domain-containing protein.	COMPASS complex protein.	0.569
A0A1B7ME58	A0A1B7N3T1	A0A1B7ME58	A0A1B7N3T1	WD_REPEATS_REGION domain-containing protein.	Histone deacetylase.	0.824
A0A1B7ME58	A0A1B7N4L9	A0A1B7ME58	A0A1B7N4L9	WD_REPEATS_REGION domain-containing protein.	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]	0.860
A0A1B7ME58	A0A1B7N4N6	A0A1B7ME58	A0A1B7N4N6	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.567
A0A1B7ME58	A0A1B7N714	A0A1B7ME58	A0A1B7N714	WD_REPEATS_REGION domain-containing protein.	Brg1-associated factor b; Belongs to the actin family.	0.462
A0A1B7ME58	A0A1B7N7A2	A0A1B7ME58	A0A1B7N7A2	WD_REPEATS_REGION domain-containing protein.	Kinase-like protein; Belongs to the protein kinase superfamily.	0.706
A0A1B7ME58	A0A1B7N7T9	A0A1B7ME58	A0A1B7N7T9	WD_REPEATS_REGION domain-containing protein.	HDAC_interact domain-containing protein.	0.586
A0A1B7ME58	A0A1B7N856	A0A1B7ME58	A0A1B7N856	WD_REPEATS_REGION domain-containing protein.	FAS1 domain-containing protein.	0.586
A0A1B7ME58	A0A1B7N8L0	A0A1B7ME58	A0A1B7N8L0	WD_REPEATS_REGION domain-containing protein.	Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.822
A0A1B7ME58	A0A1B7NB34	A0A1B7ME58	A0A1B7NB34	WD_REPEATS_REGION domain-containing protein.	Thioredoxin-like_fold domain-containing protein.	0.586
A0A1B7ME58	A0A1B7NCQ8	A0A1B7ME58	A0A1B7NCQ8	WD_REPEATS_REGION domain-containing protein.	DHS-like NAD/FAD-binding domain-containing protein.	0.499