STRINGSTRING
AMK23617.1 AMK23617.1 AMK23643.1 AMK23643.1 AMK23669.1 AMK23669.1 AMK23709.1 AMK23709.1 AMK23762.1 AMK23762.1 AMK23773.1 AMK23773.1 AMK23789.1 AMK23789.1 AMK23791.1 AMK23791.1 AMK23800.1 AMK23800.1 AMK23815.1 AMK23815.1 AMK23835.1 AMK23835.1 AMK23885.1 AMK23885.1 pyrH pyrH AMK23892.1 AMK23892.1 glmU glmU AMK23903.1 AMK23903.1 AMK23912.1 AMK23912.1 AMK23913.1 AMK23913.1 AMK23915.1 AMK23915.1 AMK23939.1 AMK23939.1 AMK23953.1 AMK23953.1 AMK23959.1 AMK23959.1 AMK23971.1 AMK23971.1 AMK23975.1 AMK23975.1 AMK23982.1 AMK23982.1 AMK23988.1 AMK23988.1 AMK23995.1 AMK23995.1 AMK24037.1 AMK24037.1 ndk ndk AMK24050.1 AMK24050.1 AMK24068.1 AMK24068.1 pnp pnp tdk tdk proB proB dnaE2-2 dnaE2-2 AMK24216.1 AMK24216.1 mraY mraY thrB thrB AMK24282.1 AMK24282.1 AMK24296.1 AMK24296.1 AMK24306.1 AMK24306.1 AMK24308.1 AMK24308.1 AMK24326.1 AMK24326.1 adk adk AMK24423.1 AMK24423.1 AMK24431.1 AMK24431.1 rpoB rpoB rpoC rpoC prs prs AMK24530.1 AMK24530.1 AMK24531.1 AMK24531.1 AMK24540.1 AMK24540.1 AMK24591.1 AMK24591.1 AMK24604.1 AMK24604.1 AMK24626.1 AMK24626.1 AMK24639.1 AMK24639.1 AMK24688.1 AMK24688.1 AMK24750.1 AMK24750.1 AMK24757.1 AMK24757.1 AMK24759.1 AMK24759.1 AMK24778.1 AMK24778.1 ackA-2 ackA-2 AMK24830.1 AMK24830.1 AMK24838.1 AMK24838.1 adk-2 adk-2 AMK24919.1 AMK24919.1 AMK24926.1 AMK24926.1 AMK24949.1 AMK24949.1 AMK24975.1 AMK24975.1 nadD nadD rsfS rsfS AMK24997.1 AMK24997.1 AMK25047.1 AMK25047.1 AMK25050.1 AMK25050.1 thiL thiL dinB dinB AMK25107.1 AMK25107.1 AMK25116.1 AMK25116.1 AMK25117.1 AMK25117.1 glnD glnD mtnK mtnK AMK25190.1 AMK25190.1 AMK25205.1 AMK25205.1 AMK25270.1 AMK25270.1 AMK25289.1 AMK25289.1 cysN cysN cysD cysD AMK25355.1 AMK25355.1 AMK25412.1 AMK25412.1 AMK25413.1 AMK25413.1 AMK25420.1 AMK25420.1 cobS cobS AMK25434.1 AMK25434.1 AMK25446.1 AMK25446.1 AMK25475.1 AMK25475.1 AMK25476.1 AMK25476.1 AMK25549.1 AMK25549.1 AMK25558.1 AMK25558.1 AMK25619.1 AMK25619.1 cysD-2 cysD-2 cysN-2 cysN-2 AMK25797.1 AMK25797.1 AMK25867.1 AMK25867.1 AMK25926.1 AMK25926.1 AMK25956.1 AMK25956.1 AMK25938.1 AMK25938.1 AMK20965.1 AMK20965.1 coaE coaE dnaQ dnaQ AMK20971.1 AMK20971.1 AMK20990.1 AMK20990.1 AMK21037.1 AMK21037.1 AMK21104.1 AMK21104.1 AMK21145.1 AMK21145.1 pal pal AMK21204.1 AMK21204.1 AMK21222.1 AMK21222.1 AMK21247.1 AMK21247.1 AMK21298.1 AMK21298.1 AMK21395.1 AMK21395.1 AMK21411.1 AMK21411.1 rpoA rpoA rbsK rbsK AMK21511.1 AMK21511.1 AMK21533.1 AMK21533.1 AMK21587.1 AMK21587.1 AMK21662.1 AMK21662.1 AMK21702.1 AMK21702.1 acpS acpS AMK21758.1 AMK21758.1 AMK21770.1 AMK21770.1 AMK21784.1 AMK21784.1 AMK21884.1 AMK21884.1 rpoZ rpoZ AMK21898.1 AMK21898.1 AMK21957.1 AMK21957.1 AMK21979.1 AMK21979.1 AMK21996.1 AMK21996.1 AMK22018.1 AMK22018.1 AMK22063.1 AMK22063.1 AMK22098.1 AMK22098.1 ppk ppk AMK22129.1 AMK22129.1 AMK22155.1 AMK22155.1 AMK22157.1 AMK22157.1 AMK22159.1 AMK22159.1 AMK22160.1 AMK22160.1 mobA mobA rph rph AMK22238.1 AMK22238.1 argB argB AMK22270.1 AMK22270.1 polA polA AMK22297.1 AMK22297.1 AMK22311.1 AMK22311.1 aroK aroK coaD coaD AMK22349.1 AMK22349.1 AMK22350.1 AMK22350.1 AMK22357.1 AMK22357.1 AMK22358.1 AMK22358.1 AMK22375.1 AMK22375.1 AMK22418.1 AMK22418.1 AMK22423.1 AMK22423.1 AMK22475.1 AMK22475.1 AMK22504.1 AMK22504.1 pgk pgk coaX coaX AMK22550.1 AMK22550.1 AMK22554.1 AMK22554.1 AMK22561.1 AMK22561.1 AMK22569.1 AMK22569.1 AMK22572.1 AMK22572.1 AMK22618.1 AMK22618.1 AMK22632.1 AMK22632.1 AMK22652.1 AMK22652.1 AMK22675.1 AMK22675.1 AMK22702.1 AMK22702.1 gmk gmk AMK22776.1 AMK22776.1 AMK22805.1 AMK22805.1 AMK22824.1 AMK22824.1 AMK22849.1 AMK22849.1 AMK22862.1 AMK22862.1 AMK22863.1 AMK22863.1 AMK22906.1 AMK22906.1 AMK22916.1 AMK22916.1 AMK22976.1 AMK22976.1 AMK22979.1 AMK22979.1 AMK22990.1 AMK22990.1 ackA ackA AMK23013.1 AMK23013.1 AMK23127.1 AMK23127.1 AMK23130.1 AMK23130.1 AMK23146.1 AMK23146.1 dnaE2 dnaE2 AMK23182.1 AMK23182.1 dnaG dnaG AMK23192.1 AMK23192.1 ppnK ppnK anmK anmK AMK23306.1 AMK23306.1 dnaG-2 dnaG-2 glgC glgC AMK23392.1 AMK23392.1 dnaX dnaX cmk cmk AMK23432.1 AMK23432.1 AMK23435.1 AMK23435.1 AMK23500.1 AMK23500.1 tmk tmk AMK23519.1 AMK23519.1 AMK23530.1 AMK23530.1 AMK23532.1 AMK23532.1 ispDF ispDF nnrE nnrE ispE ispE AMK23613.1 AMK23613.1 AMK23616.1 AMK23616.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AMK23617.1Diguanylate cyclase; COG2199 FOG: GGDEF domain. (602 aa)
AMK23643.1Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (900 aa)
AMK23669.1COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis. (452 aa)
AMK23709.1Hypothetical protein; COG0642 Signal transduction histidine kinase. (222 aa)
AMK23762.1COG2068 Uncharacterized MobA-related protein. (208 aa)
AMK23773.1COG0837 Glucokinase; Belongs to the bacterial glucokinase family. (321 aa)
AMK23789.1COG0642 Signal transduction histidine kinase. (441 aa)
AMK23791.1Two-component system sensor sporulation kinase C; COG2202 FOG: PAS/PAC domain. (653 aa)
AMK23800.1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (187 aa)
AMK23815.1Riboflavin kinase; COG0196 FAD synthase; Belongs to the ribF family. (312 aa)
AMK23835.1COG0642 Signal transduction histidine kinase. (434 aa)
AMK23885.1Phosphatidate cytidylyltransferase; COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. (262 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa)
AMK23892.1CDP-alcohol phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (258 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (449 aa)
AMK23903.1Diguanylate cyclase; COG2199 FOG: GGDEF domain. (390 aa)
AMK23912.1Hypothetical protein. (363 aa)
AMK23913.1Hypothetical protein; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (364 aa)
AMK23915.1COG1213 Predicted sugar nucleotidyltransferases. (255 aa)
AMK23939.1COG0642 Signal transduction histidine kinase. (439 aa)
AMK23953.1COG0642 Signal transduction histidine kinase. (448 aa)
AMK23959.1Multi-sensor hybrid histidine kinase; COG0591 Na+/proline symporter. (1109 aa)
AMK23971.1COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism. (287 aa)
AMK23975.1Histidine kinase; COG0642 Signal transduction histidine kinase. (422 aa)
AMK23982.1COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase. (322 aa)
AMK23988.1COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase. (306 aa)
AMK23995.1Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (884 aa)
AMK24037.1Hypothetical protein; COG2198 FOG: HPt domain. (146 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa)
AMK24050.1COG2927 DNA polymerase III, chi subunit. (150 aa)
AMK24068.1COG3920 Signal transduction histidine kinase. (188 aa)
pnpPolynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (777 aa)
tdkCOG1435 Thymidine kinase. (193 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (376 aa)
dnaE2-2DNA polymerase III alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1189 aa)
AMK24216.1COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. (525 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (357 aa)
thrBCOG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family. (330 aa)
AMK24282.1Hypothetical protein; COG2266 GTP:adenosylcobinamide-phosphate guanylyltransferase. (265 aa)
AMK24296.1Putative kinase; COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (253 aa)
AMK24306.1Signal transduction histidine kinase; COG2202 FOG: PAS/PAC domain. (690 aa)
AMK24308.12-dehydro-3-deoxygalactonokinase; COG3734 2-keto-3-deoxy-galactonokinase. (300 aa)
AMK24326.1PgsA-like protein. (230 aa)
adkCOG0563 Adenylate kinase and related kinases. (101 aa)
AMK24423.1COG4240 Predicted kinase. (269 aa)
AMK24431.1Hypothetical protein; Belongs to the UPF0434 family. (59 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1387 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1418 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa)
AMK24530.1Putative diguanylate cyclase; COG2199 FOG: GGDEF domain. (593 aa)
AMK24531.1COG0554 Glycerol kinase; Belongs to the FGGY kinase family. (488 aa)
AMK24540.1COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase). (856 aa)
AMK24591.1PfkB domain-containing protein; COG0524 Sugar kinases, ribokinase family. (333 aa)
AMK24604.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (370 aa)
AMK24626.1Phage shock protein C; COG1983 Putative stress-responsive transcriptional regulator. (61 aa)
AMK24639.1COG0642 Signal transduction histidine kinase. (470 aa)
AMK24688.1COG4643 Uncharacterized protein conserved in bacteria. (326 aa)
AMK24750.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (793 aa)
AMK24757.1Aminoglycoside phosphotransferase; COG2187 Uncharacterized protein conserved in bacteria. (486 aa)
AMK24759.1Multi-sensor signal transduction histidine kinase; COG2202 FOG: PAS/PAC domain. (607 aa)
AMK24778.1Phospholipase D/transphosphatidylase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes. (500 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
AMK24830.1COG0642 Signal transduction histidine kinase. (815 aa)
AMK24838.1Polyphosphate kinase 2. (260 aa)
adk-2Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (221 aa)
AMK24919.1Signal transduction histidine kinase; COG2203 FOG: GAF domain. (507 aa)
AMK24926.1Diguanylate cyclase; COG2199 FOG: GGDEF domain. (288 aa)
AMK24949.1Putative diguanylate cyclase; COG2199 FOG: GGDEF domain. (387 aa)
AMK24975.1Putative phage shock protein C; COG1983 Putative stress-responsive transcriptional regulator. (126 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (209 aa)
rsfSIojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (129 aa)
AMK24997.1RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (505 aa)
AMK25047.1PAS/PAC domain-containing protein; COG2202 FOG: PAS/PAC domain. (161 aa)
AMK25050.1COG2364 Predicted membrane protein. (200 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (304 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (360 aa)
AMK25107.1COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis. (798 aa)
AMK25116.1LPPG:FO 2-phospho-L-lactate transferase. (311 aa)
AMK25117.12-phospho-L-lactate guanylyltransferase CofC. (192 aa)
glnDPII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (919 aa)
mtnKMethylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (413 aa)
AMK25190.1PAS/PAC sensor signal transduction histidine kinase; COG2202 FOG: PAS/PAC domain. (391 aa)
AMK25205.1COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis. (750 aa)
AMK25270.1RNA-directed DNA polymerase (Reverse transcriptase); COG3344 Retron-type reverse transcriptase. (440 aa)
AMK25289.1COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (489 aa)
cysNBifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (635 aa)
cysDSulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. (303 aa)
AMK25355.1COG2205 Osmosensitive K+ channel histidine kinase. (888 aa)
AMK25412.1PrkA family serine protein kinase; COG2766 Putative Ser protein kinase. (647 aa)
AMK25413.1COG0642 Signal transduction histidine kinase. (456 aa)
AMK25420.1Cobalamin biosynthesis enzyme; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (170 aa)
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (236 aa)
AMK25434.1Putative ribose-phosphate pyrophosphokinase; COG0462 Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family. (294 aa)
AMK25446.1COG0642 Signal transduction histidine kinase. (757 aa)
AMK25475.1Circadian clock protein KaiC; COG0467 RecA-superfamily ATPases implicated in signal transduction. (497 aa)
AMK25476.1Signal transduction histidine kinase; COG2202 FOG: PAS/PAC domain. (670 aa)
AMK25549.1RNA-directed DNA polymerase (Reverse transcriptase). (115 aa)
AMK25558.1Ser/Thr phosphatase; COG0631 Serine/threonine protein phosphatase. (556 aa)
AMK25619.1Hypothetical protein. (272 aa)
cysD-2Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. (305 aa)
cysN-2Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (637 aa)
AMK25797.1Hypothetical protein; COG0358 DNA primase (bacterial type). (298 aa)
AMK25867.1Aminoglycoside phosphotransferase; COG3001 Fructosamine-3-kinase. (267 aa)
AMK25926.1Putative sensor protein; COG2202 FOG: PAS/PAC domain. (724 aa)
AMK25956.1COG0642 Signal transduction histidine kinase. (731 aa)
AMK25938.1COG0642 Signal transduction histidine kinase. (569 aa)
AMK20965.1PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (273 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa)
dnaQDNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (230 aa)
AMK20971.1PTS system nitrogen regulatory IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). (155 aa)
AMK20990.1COG1466 DNA polymerase III, delta subunit. (341 aa)
AMK21037.1UTP-glucose-1-phosphate uridylyltransferase; COG1210 UDP-glucose pyrophosphorylase. (299 aa)
AMK21104.1CRP/FNR family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases. (188 aa)
AMK21145.1COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes. (485 aa)
palPeptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (169 aa)
AMK21204.1Virulence-associated protein E. (282 aa)
AMK21222.1RNA-directed DNA polymerase (Reverse transcriptase); COG3344 Retron-type reverse transcriptase. (640 aa)
AMK21247.1Two-component system sensor histidine kinase; COG0642 Signal transduction histidine kinase. (338 aa)
AMK21298.1RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (621 aa)
AMK21395.1COG0263 Glutamate 5-kinase. (126 aa)
AMK21411.1Hypothetical protein; COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC. (373 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (354 aa)
rbsKPfkb domain-containing protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (301 aa)
AMK21511.1RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (621 aa)
AMK21533.1Mobile mystery protein B; COG2184 Protein involved in cell division. (195 aa)
AMK21587.1COG0642 Signal transduction histidine kinase. (446 aa)
AMK21662.1CDP-alcohol phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (200 aa)
AMK21702.1Hypothetical protein. (344 aa)
acpS4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (133 aa)
AMK21758.1Hypothetical protein. (394 aa)
AMK21770.1Genomic island protein; COG0358 DNA primase (bacterial type). (268 aa)
AMK21784.1Hypothetical protein. (244 aa)
AMK21884.1COG0642 Signal transduction histidine kinase. (440 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (114 aa)
AMK21898.1COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes. (400 aa)
AMK21957.1RNA-directed DNA polymerase; COG3344 Retron-type reverse transcriptase. (621 aa)
AMK21979.13-deoxy-manno-octulosonate cytidylyltransferase; COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase. (273 aa)
AMK21996.1COG0642 Signal transduction histidine kinase. (450 aa)
AMK22018.1COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family. (245 aa)
AMK22063.1Fructokinase; COG1940 Transcriptional regulator/sugar kinase. (306 aa)
AMK22098.1Putative signal transduction histidine kinase; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain. (368 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (712 aa)
AMK22129.1Two-component system sensor kinase CheA; COG0643 Chemotaxis protein histidine kinase and related kinases. (789 aa)
AMK22155.1GAF sensor-containing diguanylate cyclase; COG2203 FOG: GAF domain. (331 aa)
AMK22157.1PTS mannose-specific IIA component; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA. (134 aa)
AMK22159.1HPr kinase; COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism. (149 aa)
AMK22160.1COG0642 Signal transduction histidine kinase. (531 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (178 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa)
AMK22238.1COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (485 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (301 aa)
AMK22270.1Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. (483 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (928 aa)
AMK22297.1COG0527 Aspartokinases; Belongs to the aspartokinase family. (421 aa)
AMK22311.1COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family. (758 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (182 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (169 aa)
AMK22349.1COG3344 Retron-type reverse transcriptase. (411 aa)
AMK22350.1Hypothetical protein. (364 aa)
AMK22357.1Hpt domain-containing protein; COG2198 FOG: HPt domain. (125 aa)
AMK22358.1Integral membrane sensor hybrid histidine kinase; COG0642 Signal transduction histidine kinase. (936 aa)
AMK22375.1Hypothetical protein. (398 aa)
AMK22418.1RelA/SpoT domain-containing protein; COG2357 Uncharacterized protein conserved in bacteria. (336 aa)
AMK22423.1Two-component system sensor histidine kinase YesM; COG3275 Putative regulator of cell autolysis. (370 aa)
AMK22475.1Putative translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (339 aa)
AMK22504.1DNA ligase D; COG1793 ATP-dependent DNA ligase. (829 aa)
pgkCOG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (400 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (259 aa)
AMK22550.1COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. (655 aa)
AMK22554.1COG3920 Signal transduction histidine kinase. (537 aa)
AMK22561.1Multi-sensor signal transduction histidine kinase; COG2205 Osmosensitive K+ channel histidine kinase. (690 aa)
AMK22569.1Hypothetical protein. (100 aa)
AMK22572.1COG0642 Signal transduction histidine kinase. (460 aa)
AMK22618.1Signal transduction histidine kinase; COG0474 Cation transport ATPase. (568 aa)
AMK22632.1Polysaccharide chain length determinant protein; COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis. (503 aa)
AMK22652.1Putative signal transduction protein; COG2202 FOG: PAS/PAC domain. (840 aa)
AMK22675.1Hypothetical protein. (464 aa)
AMK22702.1COG3814 Uncharacterized protein conserved in bacteria. (158 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (230 aa)
AMK22776.1COG0642 Signal transduction histidine kinase. (451 aa)
AMK22805.1COG4585 Signal transduction histidine kinase. (551 aa)
AMK22824.1COG4585 Signal transduction histidine kinase. (572 aa)
AMK22849.1Putative protein-tyrosine kinase; COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis. (702 aa)
AMK22862.1Diguanylate cyclase/phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. (583 aa)
AMK22863.1Polynucleotide adenylyltransferase region; COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (403 aa)
AMK22906.1Multi-sensor signal transduction histidine kinase; COG2202 FOG: PAS/PAC domain. (626 aa)
AMK22916.1Aminoglycoside phosphotransferase; COG2187 Uncharacterized protein conserved in bacteria. (517 aa)
AMK22976.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (806 aa)
AMK22979.11-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. (326 aa)
AMK22990.1COG0642 Signal transduction histidine kinase. (252 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa)
AMK23013.1PAS sensor protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (1559 aa)
AMK23127.1DNA ligase D; COG1793 ATP-dependent DNA ligase. (418 aa)
AMK23130.1DNA ligase D; COG3285 Predicted eukaryotic-type DNA primase. (179 aa)
AMK23146.1Protein ImuB; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. (603 aa)
dnaE2DNA polymerase III subunit alpha; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1087 aa)
AMK23182.1COG3920 Signal transduction histidine kinase. (346 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (544 aa)
AMK23192.1Hypothetical protein; COG0358 DNA primase (bacterial type). (308 aa)
ppnKInorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (258 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (362 aa)
AMK23306.1COG0840 Methyl-accepting chemotaxis protein. (459 aa)
dnaG-2DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (632 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (419 aa)
AMK23392.1COG1573 Uracil-DNA glycosylase. (166 aa)
dnaXDNA polymerase III gamma and tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (536 aa)
cmkCOG0283 Cytidylate kinase. (211 aa)
AMK23432.1COG0642 Signal transduction histidine kinase. (781 aa)
AMK23435.1Nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (236 aa)
AMK23500.1Reverse transcriptase (RNA-dependent DNA polymerase); COG3344 Retron-type reverse transcriptase. (578 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa)
AMK23519.1DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication. (320 aa)
AMK23530.1COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation. (750 aa)
AMK23532.1Two-component system histidine kinase GlnL/NtrB; COG0642 Signal transduction histidine kinase. (365 aa)
ispDF2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (388 aa)
nnrEPutative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] (464 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (299 aa)
AMK23613.1Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (175 aa)
AMK23616.1COG0587 DNA polymerase III, alpha subunit. (1178 aa)
Your Current Organism:
Sphingobium sp. TKS
NCBI taxonomy Id: 1315974
Other names: S. sp. TKS
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